Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health

Can methylated B vitamins make your symptoms worse instead of better? In this episode of The Histamine Well Podcast, Joanne explains the connection between high homocysteine, histamine intolerance, methylation, and why some people react poorly to methylated nutrients.High homocysteine is associated with cardiovascular disease, cognitive decline, inflammation, and neurological health concerns — yet lowering it isn’t always simple. Many people experience headaches, anxiety, insomnia, digestive issues, skin flare-ups, or worsening histamine symptoms when taking methylfolate or methyl B12.Joanne breaks down the methylation cycle in simple terms, explains the role of histamine in nutrient tolerance, and explores how genetics such as the MTHFR gene mutation and COMT enzyme activity may influence how your body responds to methylated supplements.In this episode, you’ll learn: • What high homocysteine means and why it matters • The connection between homocysteine and methylation • Why methylated B vitamins can trigger symptoms • Histamine intolerance and supplement sensitivity • The role of MTHFR, COMT, and methylation pathways • Overmethylation vs undermethylation explained • Practical clinical insights for improving tolerance to methyl nutrientsWhether you're a practitioner, student, or navigating your own health journey, this episode offers practical education on histamine, methylation, gut health, and root-cause healing.Subscribe to The Histamine Well Podcast for expert discussions on histamine intolerance, women’s hormones, functional medicine, gut health, methylation, and integrative wellness.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Can you take Calcium-D-Glucarate while on HRT estrogen during menopause? In this short Q&A episode of The Histamine Well Podcast, Joanne explores the relationship between estrogen detoxification, hormone replacement therapy (HRT), menopause, gut health, and histamine-related symptoms.Many women are advised to take supplements that support estrogen detox, but is this always the right approach when using bioidentical hormones or estrogen therapy? Joanne explains why Calcium-D-Glucarate may not be beneficial for menopausal women on HRT, how estrogen balance works during menopause, and why understanding your hormone dose matters for symptom relief and long-term wellbeing.This episode also covers: The role of estrogen during menopause and HRT  Why over-detoxifying estrogen may worsen symptoms  The connection between beta-glucuronidase, the estrobolome, and gut microbiome health  Histamine intolerance, hormone imbalance, and menopause symptoms  Natural considerations for estrogen metabolism and hormone support  Why gut health may be more important than estrogen detox supplements If you're navigating menopause, hormone replacement therapy, estrogen dominance symptoms, histamine intolerance, or gut-related hormone imbalance, this episode offers practical clarity backed by clinical naturopathic insight. Subscribe to The Histamine Well Podcast for expert conversations on histamine intolerance, methylation, gut health, hormones, mold illness, MCAS, menopause, and functional medicine approaches to healing.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well, Joanne shares a powerful clinical case study exploring the connection between SIBO (Small Intestinal Bacterial Overgrowth), histamine intolerance, hormonal imbalance, estrogen dominance, gut health, bloating, acne, fatigue, and PMS symptoms.This episode follows the journey of a 37-year-old woman who experienced rapid body changes over two years — including unexplained weight gain, chronic bloating, severe PMS, hormonal acne, headaches, fluid retention, breast tenderness, digestive discomfort, and low energy. Through functional testing and a naturopathic treatment approach, Joanne uncovers how gut dysfunction, histamine overload, and hormone imbalance can work together to drive chronic symptoms.You’ll discover how SIBO contributes to nutrient malabsorption, inflammation, estrogen dominance, histamine intolerance, and digestive dysfunction, along with why symptoms such as bloating, fatigue, skin issues, and menstrual changes are often connected.In this episode, Joanne discusses:The link between SIBO, histamine intolerance, and hormonal imbalanceWhy bloating, PMS, headaches, and acne may stem from gut dysfunctionThe difference between hydrogen and methane SIBOHow nutrient deficiencies affect hormones, mood, and energyWhy is bowel motility essential for successful SIBO treatmentThe role of biofilms in persistent gut symptomsFunctional medicine strategies for improving gut and hormone healthWhether you are a practitioner, student, or someone navigating digestive and hormone-related symptoms, this episode offers practical insight into the deep connection between gut health, histamine, hormones, and systemic inflammation.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Can something as simple as an Epsom salt bath support detoxification, gut health, and nervous system regulation?In this Q&A episode of The Histamine Well Podcast, Joanne breaks down the clinical benefits behind Epsom salt baths (magnesium sulfate)—and why they’re often recommended for patients dealing with histamine intolerance, sulfur issues, chronic fatigue, and food sensitivities.You’ll learn how magnesium and sulfate work together in the body, how they’re absorbed through the skin, and why this gentle therapy can support everything from sleep and muscle relaxation to liver detox pathways and gut lining integrity.🎧 In this episode, you’ll learn: What Epsom salt (magnesium sulfate) actually is  How transdermal absorption supports magnesium levels  The role of sulfate in liver detoxification (sulfation pathway) Why sulfate is essential for gut lining, skin, and connective tissue health How Epsom salt baths support the nervous system and stress response Why they’re helpful for people with histamine intolerance, sulfur sensitivity, mold illness, and oxalate issues How to safely start Epsom salt baths (especially if sensitive) Epsom salt baths aren’t just about relaxation—they’re a powerful, low-cost tool to support detox pathways, reduce stress, and restore key nutrient levels without burdening the digestive system.This makes them especially beneficial for those who struggle to tolerate supplements or are dealing with complex chronic symptoms.If you’ve ever wondered whether Epsom salt baths actually “do anything”—this episode will give you a clear, science-backed answer and practical guidance.Tune in to learn how to use this simple therapy effectively and safely.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Are “healthy” foods like broccoli, garlic, eggs, or red meat making you feel worse instead of better?In this episode of The Histamine Well Podcast, Joanne breaks down one of the most overlooked root causes of food sensitivity, gut symptoms, and chronic fatigue: sulfur metabolism dysfunction.If you’ve been struggling with histamine intolerance, unexplained food reactions, bloating, brain fog, or fatigue, this episode will help you understand what may really be going on beneath the surface.🎧 In this episode, you’ll learn:What “sulfur intolerance” actually is (and why that term is misleading)The difference between sulfide, sulfite, and sulfateHow disrupted sulfur metabolism impacts your gut, energy, skin, and brainThe connection between hydrogen sulfide gas and mitochondrial dysfunctionWhy sulfur issues can trigger or worsen histamine intoleranceHidden sources of sulfur in foods, supplements, and waterThe role of methylation, molybdenum, and gut bacteriaKey symptoms of sulfur imbalance (including bloating, fatigue, headaches, and food sensitivities)Many people are told to simply eliminate more and more foods—but what if the real issue isn’t the food itself?This episode offers a functional medicine perspective to help you understand the deeper biochemical pathways behind your symptoms and why your body may be reacting the way it is.Understanding sulfur metabolism can completely shift how you approach healing—and may explain why nothing else has worked.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Do you find your anxiety worsening at night—or waking you suddenly between 2AM and 4AM with a racing heart and intrusive thoughts?In this Clarity Session Q&A, Joanne explores one of the most common patterns seen in clinic: night-time anxiety and early morning wake-ups—and why this is often more than just a psychological issue.This episode explains the physiological root causes of anxiety at night, including the critical role of blood sugar regulation, liver glycogen stores, and stress hormones like cortisol and adrenaline. When blood sugar drops overnight, your body triggers a stress response—leading to symptoms that can feel like panic attacks. You’ll learn: Why anxiety often spikes between 2AM–4AM The connection between low blood sugar and night-time panic How cortisol and adrenaline disrupt sleep  Common triggers like skipping meals, low protein intake, and caffeine use Why this pattern is especially common in perimenopause Simple strategies to stabilize blood sugar and improve sleep qualityJoanne also shares practical tips, including how a protein-based evening snack may help prevent early morning wake-ups and reduce overnight anxiety.If you’ve been struggling with disrupted sleep, anxious thoughts at night, or waking at 3AM feeling wired, this episode offers a new perspective—and actionable steps to support your body.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Are you struggling with anxiety, overwhelm, or constant nervous system dysregulation—despite normal lab results?In this episode of The Histamine Well Podcast, Joanne uncovers one of the most overlooked root causes of anxiety in women: blood sugar instability.Learn how blood sugar spikes and crashes can trigger cortisol and adrenaline, creating symptoms that feel exactly like anxiety disorders. Joanne breaks down why this often goes undiagnosed, even when glucose, insulin, and HbA1c levels appear normal.This episode explores the connection between blood sugar, hormones, histamine, gut health, and neurotransmitter production—and why women are particularly vulnerable, especially during high stress or perimenopause.You’ll also discover real-life patterns seen in clinical practice, including: High-achieving women relying on coffee and insufficient protein intake, contributing to blood sugar instability Busy mothers under-eating and overwhelmedWomen using intermittent fasting in ways that disrupt hormonesHidden links between histamine intolerance and blood sugar imbalanceIf you’ve ever felt like your anxiety “doesn’t make sense,” this episode will help you understand what’s really happening in your body—and what to do about it.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

If your blood tests are “normal”… why do you still feel inflamed?In this Q&A Clarity Session of The Histamine Well Podcast, Joanne answers a deeply important and often overlooked question: why symptoms of inflammation can persist even when CRP and ESR markers come back normal.Many people are told everything is “fine” based on standard blood work—yet continue to experience fatigue, brain fog, skin issues, gut dysfunction, and hormonal imbalances. This episode explains why that disconnect happens and what may actually be driving your symptoms.CRP (C-reactive protein) and ESR (erythrocyte sedimentation rate) are commonly used markers for inflammation—but they primarily detect acute, systemic inflammation, not the chronic low-grade inflammation seen in many complex health conditions. In this episode, you’ll learn: Why CRP and ESR can be normal despite ongoing symptoms  The difference between acute vs chronic low-grade inflammation  Common drivers of hidden inflammation (gut issues, histamine, mold, blood sugar imbalance, stress)  How inflammation can show up as skin, neurological, hormonal, and digestive symptoms  Why patients are often dismissed despite real underlying issues If you’ve ever been told “your labs are normal” but still don’t feel well, this episode will give you the clarity and validation you’ve been looking for.This is essential listening for anyone dealing with: Histamine intolerance  Chronic inflammation  Gut health issues (SIBO, candida, dysbiosis)  Hormonal imbalances  Unexplained symptoms despite normal blood tests 🎧 Subscribe to The Histamine Well Podcast for more expert insights on root-cause healing, inflammation, and complex chronic conditions.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this in-depth episode of The Histamine Well Podcast, Joanne explores why hormone symptoms often persist despite treatment, and what may be driving this beneath the surface.Drawing on clinical observation and biochemistry, Joanne explains how chronic inflammation, histamine dysregulation, and methylation imbalances interact to disrupt hormonal signaling, ovulation, and recovery.If you’ve tried supplements, improved your diet, and still experience symptoms like PMS, PMDD, anxiety, insomnia, migraines, or hormonal acne, this episode provides a deeper framework for understanding why.What You’ll LearnWhy hormones may not improve despite treatmentHow inflammation disrupts ovulation and lowers progesteroneThe connection between histamine intolerance and estrogen dominanceWhy symptoms worsen around ovulation and before your periodThe role of methylation in estrogen detoxificationDifferences between overmethylation and undermethylationWhy some supplements may worsen symptomsKey drivers behind PMS, anxiety, sleep issues, and hormonal imbalance✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Are bioidentical hormones truly “natural”—or is that just clever marketing?In this Q&A Clarity Session of The Histamine Well Podcast, Joanne breaks down one of the most common and misunderstood questions in women’s health: what bioidentical hormones actually are, where they come from, and how they differ from both synthetic hormones and herbal remedies.Many women exploring hormone replacement therapy (HRT) feel uncertain about what they’re putting into their bodies—especially when terms like “natural,” “plant-based,” and “bioidentical” are used interchangeably. In this episode, we clarify the science in a simple, grounded way so you can make informed decisions about your health.You’ll learn:What “bioidentical hormones” really meansHow hormones derived from wild yam and soy are processedThe difference between plant compounds and human-identical hormonesWhy bioidentical doesn’t mean “straight from nature”How these hormones interact with your bodyCommon misconceptions about HRT and hormone therapyIf you’ve ever struggled with hormone imbalance, menopause symptoms, or felt worse on hormone therapy, this episode will help you understand what’s actually happening beneath the surface.This is essential listening for women navigating perimenopause, menopause, or anyone questioning whether hormone therapy is right for them.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Can’t tolerate HRT? This episode explores the connection between histamine intolerance, hormone replacement therapy (HRT), SIBO, gut health, menopause symptoms, and hormone imbalance in women.Joanne Kennedy shares a clinical case study showing how histamine overload and gut dysfunction can worsen HRT side effects like brain fog, fatigue, mood swings, and skin reactions.Learn how the estrogen-histamine connection, gut health, and inflammation impact hormone tolerance—and why addressing SIBO and histamine intolerance may help restore balance.Perfect for women experiencing menopause symptoms, HRT intolerance, or ongoing hormone imbalances.🌿 In This Episode, You’ll Learn:Why histamine intolerance can worsen HRT side effectsThe connection between estrogen and histamine (and why it matters)How gut issues like SIBO drive inflammation and hormone imbalanceCommon symptoms: brain fog, fatigue, low mood, skin reactionsWhy fixing the gut can improve hormone toleranceA real clinical approach to restoring balance naturally💡 Who This Episode Is For:Women struggling with HRT side effectsThose experiencing menopause symptoms like fatigue, brain fog, and low moodAnyone with histamine intolerance or food sensitivitiesPractitioners looking to understand the gut-hormone connectionFor worldwide online consultations via Zoom, visit: www.joannekennedynaturopathy.com✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this Q&A Clarity Session of The Histamine Well Podcast, naturopath Joanne Kennedy explains the science behind sulforaphane and how it activates the NRF2 pathway, often referred to as the body’s “master switch” for protection and repair.Rather than acting as a simple antioxidant, sulforaphane works at a deeper level—helping to switch on a network of protective genes responsible for detoxification, antioxidant production, inflammation control, and immune regulation This episode breaks down complex science into simple, practical insights—perfect for both practitioners and those navigating chronic health issues.In This Episode, we discussed: What sulforaphane is and how it works in the body  The role of the NRF2 pathway in detoxification and inflammation  How sulforaphane supports antioxidant production and immune health  Why gene expression (not just supplements) matters in healing  How this applies to histamine intolerance, chronic inflammation, and gut health Who This Episode Is For: Those interested in functional medicine and natural health  People dealing with inflammation, histamine intolerance, or detox issues  Practitioners wanting to understand sulforaphane and NRF2  Anyone looking to support their body’s natural detox and repair systems ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne speaks with nutritional biochemist Dr. Christine Houghton about the GEMM Protocol (Gut Ecology & Metabolic Modulation) — a science-based approach to restoring gut health by repairing the gut lining and activating protective genes.Learn how sulforaphane, NRF2 activation, and targeted microbiome support can help improve gut inflammation, histamine intolerance, food sensitivities, and chronic illness.In this episode, you’ll learn:What the GEMM Protocol is and how it worksHow sulforaphane activates the NRF2 pathway and protective genesWhy traditional antimicrobial gut protocols can worsen dysbiosisHow gut inflammation contributes to histamine intolerance and food sensitivitiesThe role of heat-killed probiotics and immune signaling in gut repairWhy restoring the gut lining can improve conditions throughout the bodyHow diet and prebiotics support microbiome recovery Why some patients with chronic illness react to many supplements✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this Q&A Clarity Session of The Histamine Well Podcast, Joanne answers a common and often confusing question: Should I take antibiotics for SIBO?The truth is—it depends.In this episode, Joanne breaks down the two distinct patient scenarios she commonly sees in clinical practice. She explains when antibiotics may be a practical and supportive option, especially for those with lifestyle limitations, and when a deeper, more comprehensive approach may be necessary to address the root causes of SIBO.You’ll learn:When antibiotics can be helpful—and when they may not be enoughWhy SIBO often keeps coming backThe role of underlying drivers like gut motility, bile flow, and nervous system healthWhat a natural, layered approach to healing looks likeHow to determine the best path forward for your unique situationThis episode offers a balanced, practical perspective—helping you move beyond one-size-fits-all solutions and toward a more personalized approach to gut healing.If you’re struggling with recurring SIBO or unsure which direction to take, this conversation will give you clarity and guidance.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Is SIBO (Small Intestinal Bacterial Overgrowth) really the root cause of your bloating and food intolerances — or is it a downstream effect of deeper dysfunction?In this episode of The Histamine Well Podcast, Joanne explains why SIBO rarely develops in isolation and why antibiotics or herbal antimicrobials alone often fail to prevent relapse.If you’ve been stuck in the cycle of treating SIBO repeatedly without lasting improvement, this episode explores the underlying mechanisms that may be driving bacterial overgrowth in the first place.Joanne unpacks how impaired gut motility, nervous system dysregulation, low stomach acid, sluggish bile flow, estrogen dominance, mold toxicity, thyroid dysfunction, and histamine intolerance all contribute to creating the perfect environment for SIBO to thrive.Rather than focusing solely on eliminating bacteria, this episode highlights a terrain-based, root-cause approach to restoring long-term digestive health.In This Episode, We Discuss:What SIBO (Small Intestinal Bacterial Overgrowth) actually isWhy SIBO often returns after antibioticsThe migrating motor complex (MMC) and gut motilityThe vagus nerve and nervous system regulationBile flow and its antimicrobial roleEstrogen dominance and SIBOMold toxicity and mitochondrial dysfunctionThe connection between SIBO and histamine intoleranceWhy relapse happens — and how to prevent itIf you found this episode helpful, please subscribe, leave a review, and share it with someone navigating SIBO or chronic gut issues.For worldwide online consultations via Zoom, visit: www.joannekennedynaturopathy.com✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this Q&A episode, we explore how methylation affects mental health, including its impact on neurotransmitters like dopamine, serotonin, and norepinephrine. Learn how the methylation cycle regulates gene expression, hormone balance, histamine clearance, and stress resilience — and why low folate, vitamin B12, B6, and B2 can contribute to symptoms such as anxiety, depression, brain fog, fatigue, insomnia, and “wired but tired” patterns.We also discuss slow COMT activity, the link between estrogen and histamine, and how imbalances can drive mood swings, palpitations, and poor stress tolerance. Discover how real-time methylation testing (Mood Sense saliva swab) can provide personalised insights, plus how to book a Zoom consultation for deeper support.If you're struggling with histamine intolerance, hormone imbalance, anxiety, or low mood, this episode connects the biochemical dots.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne explains how Helicobacter pylori (H. pylori) can quietly drive histamine intolerance, SIBO, and hormone imbalance — even without classic ulcer or reflux symptoms.H. pylori produces urease, converting urea into ammonia and lowering stomach acid. This reduction in hydrochloric acid can impair protein digestion, weaken pathogen control, and disrupt digestive signaling — creating the perfect environment for small intestinal bacterial overgrowth (SIBO) and rising histamine levels. The result can be a “histamine storm” of inflammation and systemic symptoms.Common signs may include:Food reactionsBloating and gasHives or eczemaAnxiety and insomniaHeadachesPMS, estrogen dominance, and perimenopause flaresJoanne also discusses the pros and cons of triple therapy (antibiotics plus proton pump inhibitors), post-treatment gut repair, and natural strategies such as sulforaphane and gut-healing support.If your histamine symptoms persist despite dietary changes, this episode explores a deeper gut–histamine–hormone connection that may be driving the root cause.What You’ll Learn:How H. pylori disrupts stomach acid and digestionThe link between low stomach acid, SIBO, and histamine intoleranceWhy mast cell activation increases systemic symptomsHow histamine impacts estrogen and perimenopauseTreatment considerations and natural support options✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this short Clarity Session Q&A, Joanne explains the key differences between common magnesium forms and how to choose the right one for symptoms like anxiety, sleep issues, constipation, migraines, fatigue, muscle pain, or brain fog. Learn when each type may help—and when to avoid certain forms if you’re sensitive. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne explores how candida, yeast, and fungal overgrowth can worsen histamine intolerance and trigger ongoing mast cell symptoms.She explains how fungal-driven gut inflammation increases histamine production by activating mast cells, upregulating histidine decarboxylase (HDC), and reducing DAO enzyme activity — making it harder for the body to break histamine down.You’ll learn why antifungals alone often fail, how gut “terrain” factors like low stomach acid, poor bile flow, digestive enzyme insufficiency, microbiome imbalance, mold exposure, and chronic stress allow fungal overgrowth to persist, and how SIBO and SIFO are connected through small intestinal pH imbalance.If you struggle with histamine intolerance, sugar cravings, brain fog after carbs, bloating, or recurrent candida, this episode explains the deeper root causes — and why nervous system regulation is essential for long-term healing.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this short Clarity Session Q&A bonus episode of The Histamine Well Podcast, Joanne explains what antihistamines actually do, why symptoms often return when you stop them, and the common root causes behind histamine issues. Learn the difference between symptom suppression and true regulation of the gut, detox pathways, and nervous system. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne speaks with Rachel Scott, who developed severe food intolerances, intense histamine reactions, and unexplained chronic symptoms following mold exposure.After years of misdiagnosis and treatments that failed to address the root cause, Rachel’s health continued to deteriorate — until a simpler, more balanced approach was introduced. Rachel shares how targeted support using sulforaphane, digestive enzymes, and Epsom salt baths helped stabilize her system and gradually restore tolerance to food.Joanne explains the biochemical drivers behind mold-related illness, including sulfur metabolism, detoxification pathways, and nervous system load, and why aggressive protocols, heavy supplementation, and herbal overuse can often worsen symptoms in sensitive individuals.This conversation highlights the importance of gentle, well-timed interventions, practitioner guidance, and understanding the body’s capacity before pushing detoxification.Topics covered include:Severe food reactions and histamine intoleranceMold exposure and chronic illnessSulforaphane and detoxification supportSulfur metabolism and nervous system balanceWhy “less is more” in complex healing casesShow Notes: 🌐 Official Program Links1. The Gupta Program – Brain RetrainingThis is the main site for the limbic retraining and neuroplasticity program designed to help calm the nervous system and support recovery from chronic and sensitivity-related conditions.2. Irene Lyon – Somatic & Nervous System WorkThis is the official site for Irene Lyon, a nervous system expert who provides somatic-based exercises and education to help regulate the nervous system body-mind connection.3. Cell‑Logic – G.E.M.M. Protocol for PatientsThis page explains the G.E.M.M. Protocol (Gut Ecology & Metabolic Modulation) — an approach focused on restoring cellular health and gut-immune balance.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this Clarity Session, Joanne breaks down a common myth about the MTHFR gene, methylation, and detox. Does having an MTHFR variant mean your detox pathways are impaired? Learn how detoxification really works, how methylation fits in, and what actually supports healthy histamine balance, gut health, and energy. Perfect for anyone navigating MTHFR, chronic fatigue, or food sensitivities. ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne takes a deep dive into MARCoNS (Multiple Antibiotic Resistant Coagulase-Negative Staphylococci)—a frequently overlooked bacterial colonization that can drive chronic inflammation, histamine intolerance, and persistent, unexplained symptoms.Joanne explains how MARCoNS colonize the nasal passages, often in the context of mould-related illness, and why these bacteria are particularly difficult to eradicate due to their ability to form protective biofilms. She explores the connection between MARCoNS and symptoms such as fatigue, brain fog, migraines, anxiety, poor detoxification, and heightened inflammatory responses, especially in individuals who don’t improve despite targeted gut or histamine protocols.This episode walks listeners through how MARCoNS are identified, with a focus on nasal swab testing, and outlines evidence-informed treatment strategies, including biofilm disruptors, targeted herbal antimicrobials, and supportive therapies designed to reduce bacterial load and calm immune activation.Whether you’re a health practitioner working with complex chronic cases or an individual struggling with ongoing symptoms that don’t fully resolve, this episode provides practical insight into MARCoNS as a hidden driver of inflammation and histamine dysregulation.In This Episode, You’ll Learn:What MARCoNS are and how they impact the immune systemWhy MARCoNS are linked to chronic inflammation and histamine-related symptomsCommon signs and symptoms associated with MARCoNS colonizationHow nasal swab testing is used to identify MARCoNSTreatment approaches including biofilm disruptors and targeted antimicrobialsJoanne discusses laboratories that provide MARCoNS (Multiple Antibiotic Resistant Coagulase-Negative Staphylococci) nasal swab testing, commonly used in clinical practice to identify bacterial colonisation linked to chronic inflammation, histamine-related symptoms, and mould-associated illness.Nutripath (Australia): https://nutripath.com.au/Microbiology Dx (USA): https://www.microbiologydx.com/✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne is joined by scientist James Bradshaw for an in-depth discussion on Vitamin B12 and its critical role in human health.Together, they unpack the complex biochemistry of Vitamin B12, exploring how it supports methylation pathways, homocysteine metabolism, and neurological function. This episode provides clarity on why Vitamin B12 deficiency is often overlooked, how genetic variations can impact B12 utilization, and why choosing the correct form of B12 supplementation is essential for optimal outcomes.Joanne and James also examine the different forms of Vitamin B12—including methylcobalamin, hydroxocobalamin, adenosylcobalamin, and cyanocobalamin—discussing how each functions in the body and when one may be more appropriate than another. The conversation highlights common signs and symptoms of B12 deficiency, from fatigue and brain fog to neurological and mood-related concerns, and offers practical, evidence-informed strategies for assessing and supporting B12 status.This episode is especially valuable for health practitioners, functional medicine clinicians, and individuals seeking a deeper understanding of how Vitamin B12, genetics, and methylation intersect to influence long-term health.In This Episode, You’ll Learn:Why Vitamin B12 is essential for methylation, detoxification, and neurological healthThe different forms of Vitamin B12 and how they work in the bodyCommon and often-missed symptoms of Vitamin B12 deficiencyHow B12 supports homocysteine regulation and cardiovascular healthHow to choose the right B12 supplementation based on individual needsThe connection between genetics, methylation pathways, and B12 metabolism✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne Kennedy explains why over-methylation is becoming increasingly common, especially among women, and how it’s closely linked to COMT enzyme activity, estrogen dominance, mood disorders, and inflammation.This episode breaks down the biochemistry of methylation in a clear, practical way—exploring how estrogen affects COMT, why some people react badly to methylated B vitamins, and how over-methylation can drive symptoms such as anxiety, irritability, insomnia, nervous system overload, and chronic inflammation.Joanne also introduces the Mood Sense test as a real-time tool for assessing methylation status, helping practitioners and individuals move away from guesswork and toward personalized, symptom-aware support. With insights inspired by James Bradshaw, this episode is essential listening for anyone navigating estrogen-related symptoms, mood instability, or complex supplement reactions.What you’ll learn in this episode:Why over-methylation is becoming more common, especially in womenHow COMT enzyme activity influences mood, stress tolerance, and neurotransmitterThe connection between estrogen dominance and over-methylationCommon emotional and inflammatory symptoms linked to over-methylationWhy methylated supplements can worsen symptoms for some peopleHow the Mood Sense test can help assess methylation status in real timeKey considerations for supporting estrogen balance and calming the nervous system✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Are your hormones out of balance? In this episode of The Histamine Well Podcast, Joanne sits down with Rachel Schaefer, founder of Ginkgo Integrative Medicine, to demystify perimenopause and the role of Hormone Replacement Therapy (HRT) in supporting women’s health.They explore what actually happens during hormone fluctuations in perimenopause, how to recognize estrogen dominance, and the benefits and risks of estrogen, progesterone, and testosterone therapy. Rachel shares practical insights on how personalized care, detailed hormone testing, and integrative medicine can help women navigate this transitional stage with confidence.You’ll learn how early intervention with the right HRT protocol can improve energy, mood, sleep, and long-term wellbeing—plus how to avoid common pitfalls with synthetic hormones, patches, and oral estrogen.Whether you’re just entering perimenopause or already considering HRT, this episode offers a clear, empowering look at how to restore hormonal harmony and thrive through midlife.Learn more about Rachel’s integrative approach to hormone health and women’s wellbeing:Website: https://www.ginkgointegrativemedicine.com/ Instagram: @ginkgointegrative🧪 Rachel’s Recommended Annual Serum Lab Panel (Age 40+)Done fasting, ideally once per year. Tracks hormonal shifts & key biomarkers:CBC w/ diff · Ferritin, TIBC, Iron sat · CMP · GGT · SHBG · DHEA-S · Free & Total Testosterone · Estradiol LC/MS (Cycle Day 2–3) · FSH (Day 2–3) · LH · Progesterone LC/MS (Day 20–21) · Homocysteine · MMA · HSCRP · Insulin · HbA1c · ApoB · Lp(a) · TSH · Free T4 · Free T3 · rT3 · TPO antibodies · ANA · Vitamin DAdditional testing based on the case: DUTCH · Tiny Health GI Pro · Mira · 3x4 Genetics · Total Tox Burden · DEXA · OATS · Mood Sense💡 At-Home Hormone Tracking — Listener DiscountRachel checked in with Mira, a home-based hormone urine testing device, to offer a special 20% off discount for listeners of The Histamine Well Podcast.🔸 Public Discount Code: 2GINGKO20🔸 Mira Website: www.miracare.com✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Is your home secretly affecting your health? In this episode of The Histamine Well Podcast, Joanne’s colleague Melanie Peers sits down with Building Biologist Jo Lia to uncover the hidden dangers of mold, electromagnetic fields (EMF), and poor indoor air quality.Jo shares her journey into building biology and explains how unseen environmental factors—like hidden mold spores or constant EMF exposure—can impact your immune system, mood, and energy levels. Together, they break down what you can do to make your home a truly healthy space, from proper mold testing and remediation to simple steps that minimize EMF radiation in your daily life.If you’ve struggled with chronic inflammation, fatigue, allergies, or unexplained symptoms, this episode will help you connect the dots between your home environment and your health.What You’ll Learn:How to identify the early signs of mold in your homeThe truth about EMFs and how they affect your healthSimple ways to reduce EMF exposure from Wi-Fi and devicesWhat to do if you suspect mold contamination — and how to remediate safelyWhy modern airtight homes can worsen indoor air qualityHow to improve ventilation and maintain clean indoor airHow to find and work with a certified Building BiologistPractical tips for creating a toxin-free, health-supportive living environmentConnect with Jo Lia:🌿 Website: https://www.notoxrox.com/ 📸 Instagram: @notoxrox 📘 Facebook: facebook.com/notoxroxAustralian Society of Building Biologists: https://www.asbb.org.au/✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast,  Joanne sits down with Rosaria Nithart, a French-based naturopath specializing in digestive health, to uncover the complexities of Hydrogen Sulfide SIBO—one of the most misunderstood forms of Small Intestinal Bacterial Overgrowth (SIBO).Together, they break down how Hydrogen Sulfide SIBO differs from hydrogen- and methane-dominant SIBO, exploring the unique bacteria and biochemical pathways involved. Rosaria shares her step-by-step naturopathic framework for identifying, testing, and treating Hydrogen Sulfide SIBO naturally. The conversation also dives deep into the role of sulfur metabolism, oxalates, and molybdenum in managing symptoms and restoring gut balance.Listeners will learn:The root causes and drivers behind Hydrogen Sulfide SIBOHow to identify key symptoms and understand testing limitationsThe connection between sulfur, oxalates, and bacterial imbalancesPractical treatment strategies that support gut healing without extreme dietsHow Hydrogen Sulfide SIBO links to UTIs, histamine intolerance, and detox pathwaysWhether you’re a practitioner seeking deeper clinical insights or a patient navigating chronic gut issues, this episode offers a clear, actionable approach to understanding and managing Hydrogen Sulfide SIBO naturally. Connect with Rosaria Nithart:Website: rosarianithart.com | rosarianithart.itFacebook: facebook.com/rosaria.nithartInstagram: @rosarianithartnaturopatheBreath Tests for Hydrogen, Methane & Hydrogen Sulfide:Trio Smart (USA / Canada)– Trio-Smart® — The only 3-Gas SIBO Breath Test: https://www.triosmartbreath.com/Nordic Labs (Europe) – https://nordiclabs.com/EProduct.aspxInvivo Healthcare (UK): https://invivohealthcare.com/Teletest (Spain): https://www.teletest.es/ | https://www.facebook.com/teletest/✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne Kennedy sits down with physiotherapist and neuro-rehabilitation specialist Jacqui Raadschelders to explore the link between nervous system dysregulation and chronic illness.You’ll learn how the limbic system, vagus nerve, neuroplasticity, and brain retraining techniques play a vital role in recovery from conditions influenced by trauma, mold exposure, and stress. Jacqui shares her journey from traditional physiotherapy to a holistic, trauma-informed approach—highlighting the impact of emotions, beliefs, and environment on healing.Key topics include:Fight, flight, and freeze responsesThe role of the limbic system in chronic illnessPractical vagus nerve toning exercisesEmotional regulation and belief system shiftsBrain retraining for long-term resilienceTailored strategies to regulate and recalibrate the nervous systemWhether you’re a practitioner, student, or someone navigating chronic illness, this conversation offers practical tools and evidence-based insights for restoring balance and supporting your nervous system health.Enrol in the Regulate Your Nervous System online program and receive 10% off with the code JOANNE10. This program is for anyone navigating chronic illness, burnout, stress or persistent symptoms who’s ready to understand their body in a new way. Enrol here ✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, Joanne is joined by colleague Melanie and patient Tracy, who shares her powerful story of navigating the challenges of oxalates, histamine intolerance, adrenal fatigue, and blood sugar imbalances.Tracy’s journey highlights the complex relationship between oxalates, adrenal and blood sugar imbalances, and oxalate dumping symptoms. With support from Melanie, she has worked through paradoxical reactions to magnesium and B6, learned strategies for managing sulfur metabolism, and discovered the importance of patience and persistence in recovery.Melanie provides expert insights into identifying oxalate issues, tailoring dietary strategies, and supporting detoxification pathways. Together, the conversation emphasizes the importance of professional guidance, careful supplementation, and tracking progress when addressing oxalates.Whether you’re a practitioner seeking functional medicine insights or someone personally struggling with oxalates, histamine intolerance, or methylation challenges, this episode offers practical advice and encouragement to support your healing journey.What You’ll Learn in This EpisodeHow oxalates affect adrenal health and blood sugar balanceWhat to know about oxalate dumping symptoms and how to manage themThe role of sulfur metabolism and detox pathways in oxalate sensitivityWhy do some people experience paradoxical reactions to magnesium and B6Dietary and lifestyle strategies for long-term oxalate managementThe link between oxalates, histamine levels, and methylationWhy professional support is crucial for navigating complex health issuesWhy This Episode MattersOxalates are often overlooked in discussions about chronic health, but they can play a major role in gut health, nutrient absorption, adrenal function, and histamine intolerance. Tracy’s story shows how challenging—but also how rewarding—it can be to address these issues with the right support and strategies.If you’ve been struggling with fatigue, blood sugar swings, or unexplained reactions to supplements, this conversation offers valuable guidance.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well Podcast, host Joanne Kennedy and guest Mariella Gebhardt unpack the nuances of medical testing in functional medicine—and why lab results alone don’t always tell the full story.From histamine intolerance and methylation issues to gut health, Candida, mold exposure, and hormone imbalances, Joanne and Mariela explore the limitations and benefits of testing while emphasizing the importance of case history, symptoms, and environmental factors in shaping treatment.They break down popular tests—including organic acids tests (OAT), microbiome testing, genetic testing, thyroid panels, iron tests, and hormone testing—highlighting when they’re useful, what they may miss, and how to interpret them in real-world practice.Whether you’re curious about functional medicine, women’s hormones, SIBO, oxalates, DAO enzyme activity, or vitamin B12 deficiency, this episode offers clarity on when testing helps—and when it can be misleading.What You’ll Learn in This Episode:Why clinical context matters more than test results aloneHow to approach Candida, mold, and mycotoxin testingThe role of the DAO enzyme in histamine breakdownPitfalls of genetic and gene testing for methylationHow to interpret iron tests, thyroid panels, and hormone markersInsights on organic acids, oxalates, and gut health testingIf you’ve ever wondered whether your test results reflect the whole picture—or how to navigate functional medicine testing with confidence—this conversation will help you understand the bigger picture.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Could mold be the missing link in your chronic health puzzle?In this episode of The Histamine Well Podcast, Joanne speaks with Melanie Peers about the hidden impact of mold illness and how it can silently drive histamine intolerance, food sensitivities, and long-term inflammation.You’ll discover how mold exposure can:Raise histamine levels and trigger mast cell activationDisrupt methylation and detoxification pathwaysCause oxalate buildup and sulfur imbalancesLead to neurological, digestive, respiratory, and skin symptomsMelanie shares how to spot the difference between everyday mold allergies and systemic mold-related illness, how to test for mold in your home and body, and what a mold detox protocol can look like in real life.Whether you’re a health practitioner or someone struggling with unexplained symptoms, this episode gives you practical strategies for identifying mold, removing exposure, and supporting recovery.What You’ll Learn in This EpisodeKey symptoms of mold illness you might be missingHow mold drives histamine intolerance and CIRS (Chronic Inflammatory Response Syndrome)The mold–oxalate connection and why it matters for gut healthEffective mold testing for your home and bodyMold detox strategies and the role of sulfur in recoveryEnvironmental tips for reducing mold exposureReal-life case studies of mold-related illness and recovery✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Perimenopause isn’t just a physical transition — it’s an emotional, spiritual, and energetic shift. In this empowering episode of The Histamine Well Podcast, Joanne speaks with Claire Tait, a holistic kinesiologist and intuitive energy healer, about how to navigate perimenopause with greater balance, calm, and self-awareness.Claire shares her expertise on how kinesiology, reiki, acupressure, yoga, and other holistic practices can support women during this powerful life stage. You’ll learn how to regulate your nervous system, address anxiety naturally, and embrace the spiritual metamorphosis of perimenopause.This conversation is filled with practical rituals, personal insights, and empowering perspectives to help you surrender to the changes, reconnect with yourself, and thrive during midlife.What You’ll Learn in This Episode:Emotional & spiritual transitions of perimenopauseHow self-awareness supports hormonal and emotional healthKinesiology: blending Eastern and Western healing methodsReiki, acupressure, and yoga for grounding and calmNatural approaches to easing anxiety during perimenopauseThe role of the nervous system in healingHow intermittent fasting impacts women’s healthEmbracing aging and rejecting societal pressuresThe energetics of female empowerment✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Can histamine be the hidden reason behind your anxiety?In this episode, I break down how histamine acts as a neurotransmitter in the brain — and why an overload can leave you wired, anxious, and unable to relax. We dive into how methylation, estrogen, mold, and gut inflammation (including SIBO and oxalates) all feed into the histamine-anxiety loop.Whether you're a practitioner treating patients with anxiety or someone who’s tried everything to feel better — this episode gives you a deeper lens into the hidden biochemical drivers of mental health symptoms.If you've ever felt overstimulated, panicked, or like anxiety hits out of nowhere, you're going to want to hear this one.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

We break down how disrupted sulfur metabolism can mimic histamine symptoms—severe bloating, crushing fatigue, joint pain, brain fog, skin flushing—and why reactions to garlic, onions, eggs, brassicas, NAC, and glutathione are key clues.You’ll learn the roles of sulfite/sulfide vs. sulfate, SUOX + molybdenum, B12, mitochondria, hydrogen sulfide overgrowth, and environmental drivers like mold and oxalates. We also cover testing pointers (homocysteine, stool, OAT), why low-sulfur diets are only a short-term tool, and practical next steps for practitioners and patients.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this deeply personal and powerful episode, Joanne sits down with patient Anastasia Lamont to explore her journey through PMDD (Premenstrual Dysphoric Disorder), histamine intolerance, and overmethylation. Anastasia opens up about the debilitating symptoms she endured — from suicidal ideation and extreme fatigue to chronic pain and severe skin conditions — and how her life transformed through targeted naturopathic treatment. Together, they unpack the emotional and clinical journey, revealing the role of diet, supplements, and real-time methylation testing in stabilizing mood and reclaiming wellness.This is a must-listen for anyone living with PMDD or supporting someone who is — and for practitioners looking to understand the powerful intersection between mood, hormones, and histamine.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

Struggling with persistent SIBO symptoms or unsure where to start with natural treatment? In this episode, I break down exactly how I treat SIBO in clinic — from diet and herbs to overlooked factors like biofilm, enzymes, histamine, and oxalates.Whether you're a health practitioner, student, or someone personally dealing with SIBO, you'll walk away with a deep understanding of the step-by-step process required for real, lasting results — not just temporary relief.What I Cover:✔️ Why a low FODMAP diet is non-negotiable if you're treating SIBO naturally✔️ How to use testing — and retesting — to guide effective treatment✔️ The best herbs for hydrogen and methane SIBO (and why they differ)✔️ The role of SIFO (Small Intestinal Fungal Overgrowth) and how to spot it✔️ Why addressing biofilm is essential for treatment success✔️ How digestive enzymes (including brush border support) accelerate healing✔️ The hidden role of histamine intolerance in stubborn cases✔️ Why oxalates can spike on a low FODMAP diet — and what to do about it✔️ What to do when the migrating motor complex (MMC) isn’t working✔️ The best prokinetics, binders, and enzyme supplements I use in practice✔️ When and how to safely reintroduce foods after treatment✔️ What recurring SIBO is trying to tell you✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well, we're diving into one of the most overlooked root causes behind symptoms like fatigue, histamine intolerance, hormonal imbalance, oxalate sensitivity, mood swings, and chronic inflammation: acid load and mineral depletion.You'll learn:Where acidity in the body comes from — from diet and inflammation to mitochondrial dysfunction and gut dysbiosisHow acid load disrupts key systems, including hormones, energy, detoxification, and neurotransmittersWhy histamine and oxalates are inherently acidic — and how that ramps up symptoms in sensitive individualsThe role of bicarbonate and minerals in buffering acid and maintaining systemic pH balanceHow to interpret functional blood markers like bicarbonate and the anion gap (and what they actually mean)Why simply adding more supplements won’t fix a stressed nervous system or mineral-depleted biochemistryWhich alkalizing mineral formulas and mitochondrial supports Joanne recommends in clinical practice — including Basica, Orthoplex Alkamin, and ATP FuelWhether you're a practitioner, student, or someone deep in their own healing journey, this episode will shift how you view symptoms and recovery — especially if you’ve hit a wall despite ‘doing all the right things.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well, Joanne dives deep into Premenstrual Dysphoric Disorder (PMDD) and severe PMS — the kind that can leave you feeling anxious, depressed, exhausted, and unlike yourself for half the month.Joanne shares insights from her clinical practice to explore what’s really going on beneath the surface, including:Hormone imbalances like estrogen dominance and low progesteroneInflammation, oxidative stress, and their impact on ovulationNutrient deficiencies that affect mood and hormone functionThe surprising role of methylation imbalances — particularly overmethylation — and how this biochemical pathway can disrupt neurotransmitters and moodShe also introduces the concept of testing methylation in real time, and shares a powerful patient story that shows how personalized treatment can dramatically improve mood and cycle symptoms.Whether you’ve been diagnosed with PMDD or you just know your PMS isn’t normal, this episode offers a fresh perspective and hope for more stable cycles and moods.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of The Histamine Well, host Joanne speaks with Amanda Bradshaw, co-founder of Mood Sense, to explore the critical role methylation plays in mood, mental health, and hormonal transitions like perimenopause. Joanne shares her clinical insights and surprising test results showing that some patients assumed to be under-methylators were actually over-methylating—changing the course of their treatment.Amanda opens up about her personal health journey through perimenopause and how balancing her methylation significantly improved symptoms like mood swings and hot flushes. Together, they unpack how methylation imbalances can impact not just mental health, but also relationships, family dynamics, and even parenting—especially in neurodivergent households.Listeners will also gain practical guidance on how the Mood Sense test works, and how diet, lifestyle, and targeted supplements can help restore balance and support emotional resilience.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode, Joanne Kennedy discusses a comprehensive case study of a patient with various symptoms like abdominal pain, migraines, and joint pain who was incorrectly suspected of having mold and oxalate problems. The root cause turned out to be gluten intolerance. Joanne explains the impact of gluten on the immune system, highlighting how it can cause significant inflammation and histamine issues. She differentiates between celiac disease, wheat allergy, and non-celiac gluten sensitivity, explaining their symptoms, testing methods, and impacts on histamine production. Joanne also provides insights into diagnosing these conditions and emphasizes the importance of closely examining patients' diets before attributing symptoms to more complex conditions like mold or oxalate issues.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by Amber Romanic, an expert in emotional eating, digestion, and hormonal health.Amber shares her personal journey overcoming emotional eating and discusses how it impacts gut health and increases histamine levels.They explore common emotional eating triggers, the role of high cortisol, and the pitfalls of extreme diets like intermittent fasting.Amber offers practical tips on managing emotional eating, the importance of healing one's relationship with food, and why self-care and setting healthy boundaries are crucial.Additionally, they touch on the unique challenges women face during different phases of their menstrual cycles and why maintaining a balanced approach is essential for overall well-being.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne explores the surprising link between high histamine levels and hypoglycemia. She details how elevated histamine can disrupt blood sugar regulation through various mechanisms, including overstimulation of insulin production, suppression of glucagon, and cortisol dysregulation. Joanne also offers practical advice on managing high histamine and blood sugar levels through diet, stress management, and lifestyle changes. Tune in to learn more about identifying and addressing histamine-related blood sugar crashes.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by her colleague Melanie Peers to discuss the relationship between small intestinal bacterial overgrowth (SIBO) and histamine intolerance. They explore the complexities of SIBO, its causes, symptoms, and its impact on histamine levels in the body. Joanne and Melanie also delve into related issues such as the role of the migrating motor complex, the influence of stress, dietary impacts, and the significance of mold, oxalates, and sulfur in exacerbating histamine symptoms. Practical advice on diagnosis, dietary adjustments, and treatment options is provided, making this episode an invaluable resource for both practitioners and individuals seeking to manage their gut health and histamine-related conditions.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, host Joanne Kennedy delves into the significance of digestive enzyme deficiencies in managing histamine intolerance and chronic gut issues like SIBO. Joanne explains the critical roles of hydrochloric acid, pancreatic enzymes, and bile acids in maintaining a healthy digestive system, and how their insufficiencies can lead to increased histamine levels and poor gut health. The episode covers the symptoms, causes, and solutions for enzyme deficiencies, emphasizing the importance of proper enzyme supplementation. Joanne also shares insights into the impacts of stress, diet, and specific medications on enzyme production. This episode is a must-listen for those looking to better understand and manage their digestive health and histamine levels.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well podcast, Joanne dives into the connection between methylation, detoxification, and gallbladder health. Joined by nutritionist Olivia Haas, they discuss how impaired methylation affects bile flow, leading to gallbladder dysfunction and increased histamines. Olivia explains the essential role of the gallbladder in digestion, detoxification, and overall health. They cover early warning signs of gallbladder issues, appropriate testing, and the interplay between estrogen dominance, mold, and oxalate sensitivities. Practical recommendations for dietary and supplement support for gallbladder and liver health, both pre- and post-surgery, are also discussed. Olivia also speaks about her specialized programs and memberships designed to assist patients with gallbladder concerns. This episode is packed with insights and actionable advice for both practitioners and patients.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne does something a little different. She shares her step-by-step approach for rapidly lowering your histamine bucket while working toward identifying and treating the root cause. This episode is packed with clinical gems and practical strategies—perfect for both patients and practitioners.In this episode, you’ll learn:Why a low histamine diet is your first line of defense—and where to find a reliable food listHow DAO enzymes like Seeking Health Histamine Digest help reduce food-based histamineThe role of mast cell stabilizers like vitamin C and quercetin (e.g. RN Labs QuerceSorb, Thorne Quercetin)How Saccharomyces boulardii can support histamine breakdown and gut resilienceWhy SIBO + histamine requires a different approach—including what foods to avoid (spoiler: rice!)What to do if you’re constipated and why moving your bowels is essential to reduce histamineThoughts on prokinetics like ginger, Iberogast, and low-dose naltrexone for sluggish gut motilityWhat to do when bloating persists despite a perfect diet and supplementsThe hidden impact of oxalates—and how to avoid triggering a painful oxalate dumpThe difference between short-term relief and long-term healing✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by Naturopath Mariela Gebhardt from Austria to discuss a fascinating and complex case. Initially thought to be related to SIBO, Mariela shares how, despite seeing early improvement in her patient's gut health, she remained in a heightened anxious state and developed an unusual symptom: toe pain.Mariela identified this as an oxalate issue, which was later confirmed through Organic Acids testing. This discovery prompted Mariela to inquire further about mould exposure, which quickly became clear as a significant factor.Mariela humbly acknowledges that the mould and oxalate issue should have been identified during the initial consultation, but, due to her lack of training in this area at the time, it wasn’t immediately apparent. However, after mentoring with Joanne and her colleague Melanie Peers, her perspective shifted, and she now approaches these cases with greater insight.This episode is a must-listen for anyone dealing with chronic histamine issues, as well as practitioners and students interested in more complex cases.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, host Joanne delves into the often-overlooked topic of low homocysteine levels. Joanne explains that while high homocysteine is commonly flagged for its cardiovascular risks, low homocysteine is seldom discussed despite its significant implications for health. She explores how low homocysteine can indicate sulfur depletion, often linked to issues such as oxalate toxicity and mold illness. The episode covers the methylation process, the importance of methionine, and the roles of cysteine, glutathione, and taurine. Joanne also discusses the impact of stress, diet, and poor absorption on homocysteine levels and underscores the connection between oxalates and sulfur depletion. Whether you are a practitioner or navigating your personal wellness journey, this episode provides actionable insights into understanding and addressing low homocysteine to improve overall health.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well, Joanne is joined by scientist James Bradshaw to discuss the complexities of methylation and its critical role in genetics, mood, and overall health. James shares his extensive background in biochemistry and cellular biology and introduces Mood Sense, the first saliva test for assessing methylation-related mood disruptions. They explore the essentials of methylation, its impact on neurotransmitter production, and the difference between over and under methylation. The episode also delves into genetic mutations, environmental factors affecting methylation, and practical approaches to managing methylation in clinical practice. Listeners gain insights into the role of methylation in various chronic health conditions and how personalized testing can lead to better health outcomes.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!