5: Mark Cuban on Fixing Healthcare, Cost Plus Drugs, AI, and the Broken Prescription System

Mark Cuban joins Seth Sternberg for a deep conversation on why America’s healthcare system became so expensive, opaque, and difficult to navigate—and what it will actually take to fix it.Drawing from his experience building Cost Plus Drugs, Mark explains how Pharmacy Benefit Managers (PBMs) quietly reshaped the prescription drug market, why transparency matters more than marketing, and how direct-to-consumer healthcare models can remove friction and lower costs for patients.They also explore why so many successful technology entrepreneurs eventually move into healthcare, how AI is changing medicine and patient decision-making, and why aging populations will become one of society’s defining challenges over the next several decades.In this episode:Why Mark Cuban chose healthcare after decades in tech and investingHow PBMs control prescription drug pricingThe real story behind Cost Plus DrugsWhy transparency beats complexity in healthcareHow direct contracting could reshape healthcare servicesThe role of AI in patient care and medication managementWhy aging and senior care will define the future economyThe entrepreneurial mindset behind solving hard societal problemsAbout Mark Cuban: Mark Cuban is an entrepreneur, investor, and co-founder of Mark Cuban Cost Plus Drug Company. He previously co-founded Broadcast.com, which was acquired by Yahoo in 1999, and is widely known from Shark Tank and as the former majority owner of the Dallas Mavericks.Connect with Mark Cuban:LinkedIn: https://www.linkedin.com/in/mark-cuban-06a0755b/X: https://x.com/mcubanInstagram: https://www.instagram.com/mcuban/Connect with Seth Sternberg:LinkedIn: https://linkedin.com/in/sethjsListen to Aging Intelligence:Apple Podcasts: https://bit.ly/41idKLJSpotify: https://bit.ly/3R6LPwcYouTube: https://bit.ly/4buRqDn