63: Inside the Microbiome: Terrain-Based Healing, Gut Intelligence & Future Medicine | Kiran Krishnan

Hey Functional Friends!This week I’m speaking with one of my favorite humans and longtime mentors, the brilliant Kiran Krishnan — research microbiologist, educator, and co-founder of Microbiome Labs. We explore the evolution of functional medicine, the rise of evidence-based holistic practice, and how AI and new technologies are reshaping research. Kiran breaks down the future of microbiome testing, the truth about stool analysis, and why understanding terrain and sequencing interventions is key to better clinical outcomes. We also dive into his new Practitioner Microbiome Mastery Course, the importance of systems-based thinking, and how practitioners can elevate their results through data-driven, root-cause healing. As always, this was an inspiring, mind-expanding conversation — you’re going to love it.00:00 – Intro + setting the stage for today’s episode02:25 – Welcoming Kiran Krishnan back to the show03:50 – Innovation, AI, and the future of clinical trials06:00 – Elevating the holistic and functional medicine space with real evidence09:00 – The need for practitioner education and Kiran’s new Microbiome Mastery course12:30 – Why clinicians struggle with complexity and root-cause sequencing17:00 – Stool testing: diagnostic limits, pros/cons, and what it really tells us23:20 – Whole-genome vs PCR testing and the terrain-based model31:10 – The “Whack-a-Mole” trap of chasing pathogens39:00 – Why terrain and missing functions matter more than pathogens46:00 – Understanding phyla ratios and ecosystem-level patterns50:00 – How Kiran’s course teaches systems biology and clinical sequencing56:00 – Foundational interventions and order of operations in healing57:00 – The real deal on Urolithin A and microbiome-derived compounds1:00:00 – Functional applications, muscle building, nitric oxide + future projectsJoin the Waitlist for Kiran's Microbiome Clinical Science Certificate Program: https://learn.rebelhealth.co/mcsc-waitlistCheck Out Brendan:Brendan’s Instagram: ⁠⁠⁠⁠⁠@the_holistic_savage⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Brendan Online⁠⁠⁠⁠⁠- - - Send in a voice message:⁠⁠⁠⁠⁠http://podcasters.spotify.com/pod/show/holisticsavagepodcast/message