643. Mastering GLP-1s in Peri and Menopause: What 95% of Women Are Doing Wrong

If you're eating well, exercising, prioritizing protein, and still struggling with weight gain in perimenopause or menopause, you're not alone. In this episode, I sit down with hormone expert Karen Martel to talk about why midlife weight gain is often more complex than calories in and calories out. We discuss how shifts in progesterone, estrogen, testosterone, thyroid function, and stress hormones can impact metabolism, cravings, muscle mass, and insulin sensitivity. We also explore hormone replacement therapy, insulin resistance, and the growing use of GLP-1 medications for weight loss. Karen shares what she sees most often in practice, why some women continue to struggle despite doing everything right, and how to think about weight loss resistance through a broader hormonal and metabolic lens. If you've been wondering why your body feels different in midlife, this episode is for you. What you’ll learn: Why weight loss becomes more challenging during perimenopause and menopause How changing hormone levels affect metabolism and body composition The connection between sleep, stress, cravings, and weight gain Why insulin resistance can develop even in women with healthy habits How thyroid health influences weight and metabolic function What hormone replacement therapy can and cannot do for weight loss When GLP-1 medications may be appropriate for midlife women Signs that deeper metabolic or hormonal factors may be contributing to weight loss resistance After listening, you'll have a better understanding of the hormonal changes that shape weight and metabolism in midlife, along with practical considerations for supporting your health. Subscribe, share the episode, and send it to a friend who may be navigating the same challenges. Resources: Connect with Karen: https://karenmartel.com/  Grab your Thyroid Fixer here: https://betterlifedoctor.com/ New here? Use code LISTEN20 for 20% off your first order Returning customers can use code LISTEN10 for 10% off SHOP DR. AMIE’S FIXXR® SUPPLEMENTS: betterlifedoctor.com  LET'S GET YOUR LIFE BACK...Connect with Dr. Amie Hornaman Book a free thyroid and hormone solution call: https://dramiehornaman.com/pages/book-a-call  CHECK OUT MY FREEBIES... JUST CLICK BELOW Thyroid Optimization Guide: https://health.dramie.com/thyropause  7 Day Thyroid Healing Kickstarter: https://fixyourthyroid.com/7daykickstarter  Thyroid on Trial: https://health.dramie.com/thyroid-on-trial-optin  RATE, REVIEW AND FOLLOW ON APPLE PODCASTS Show your love for Dr. Amie and The Thyroid Fixer Podcast! If you’re enjoying our journey together, I’d be thrilled if you could take a moment to rate and review the show on Apple Podcasts. Your support helps me reach and help more people just like you, guiding them towards their optimal selves! Just click HERE, scroll all the way down, give us those 5 stars, and share what you enjoy about my episodes in a review. Haven’t subscribed yet? Make sure to follow The Thyroid Fixer Podcast to catch all the new episodes that come out every week. Follow HERE and never miss out on a moment of the journey! CONNECT WITH ME ON SOCIAL MEDIA: Join my exclusive Facebook Group and get questions answered LIVE weekly, Just Fix Your Thyroid, for a Community of HOPE and SUPPORT in your thyroid journey. https://www.facebook.com/groups/dramie/  Like me on Facebook: Amie Hornaman Nutrition and Functional Medicine Subscribe on YouTube: Dr. Amie Hornaman Follow me on Instagram: @dramiehornaman