EPISODE · Dec 19, 2025 · 14 MIN
71: Repetitive Negative Thinking and Alzheimer's Disease Risk
from Listen, Learn, Adapt · host Anthony Novello
This episode does a deep dive into an article that investigates the Cognitive Debt hypothesis, which suggests that repetitive negative thinking (RNT) serves as a modifiable risk factor for Alzheimer’s disease. Marchant NL, Lovland LR, Jones R, et al. Repetitive negative thinking is associated with amyloid, tau, and cognitive decline. Alzheimers Dement. 2020;16(7):1054-1064. doi:10.1002/alz.12116Follow Dr. Anthony Novello, PT, DPT@anthonynovello.dpt
What this episode covers
This episode does a deep dive into an article that investigates the Cognitive Debt hypothesis, which suggests that repetitive negative thinking (RNT) serves as a modifiable risk factor for Alzheimer’s disease. Marchant NL, Lovland LR, Jones R, et al. Repetitive negative thinking is associated with amyloid, tau, and cognitive decline. Alzheimers Dement. 2020;16(7):1054-1064. doi:10.1002/alz.12116Follow Dr. Anthony Novello, PT, DPT@anthonynovello.dpt
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71: Repetitive Negative Thinking and Alzheimer's Disease Risk
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