91: NAD+ Metabolism and Mitochondrial Homeostasis in Agin...

What this episode covers

This episode does a deep dive into an article on Nicotinamide adenine dinucleotide (NAD+), which is an essential coenzyme that facilitates vital biological processes such as energy production, DNA repair, and metabolic balance. Because NAD+ levels naturally decline with age, researchers are investigating various precursors like NR and NMN, alongside enzyme inhibitors, to restore cellular health.Yusri K, Jose S, Vermeulen KS, Tan TCM, Sorrentino V. The role of NAD+ metabolism and its modulation of mitochondria in aging and disease. npj Metab Health Dis. 2025;3:26. doi:10.1038/s44324-025-00067-0Follow Dr. Anthony Novello, PT, DPT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@anthonynovello.dpt⁠⁠

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This episode is 18 minutes long.

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This episode was published on February 17, 2026.

What is this episode about?

This episode does a deep dive into an article on Nicotinamide adenine dinucleotide (NAD+), which is an essential coenzyme that facilitates vital biological processes such as energy production, DNA repair, and metabolic balance. Because NAD+ levels...

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