A New Era Against Cancer, Dementia, And Aging With Genes episode artwork

EPISODE · Sep 11, 2025 · 1H 4M

A New Era Against Cancer, Dementia, And Aging With Genes

from Ayık Kafa · host Longevilab

In this episode of the Sober Head Podcast, Dr. Esra Çavuşoğlu, PhD, hosts world-renowned oncologist, gene therapy pioneer, and founder of Triple Helix Science, Dr. Patrick E. Sewell, MD, at the Sober Head studio in Istanbul. Dr. Sewell shares from his own experience how the future of medicine is shifting from managing disease to truly curing it.He talks about his groundbreaking work in gene addition therapy, stem cells, and precision oncology, along with real stories of bringing back to life patients who were told nothing more could be done. The podcast also explores how gene therapy can reverse cognitive decline and muscle loss, as well as the advances in treating diabetes, obesity, and heart disease. Dr. Sewell also explains why the genes klotho, folistatin, and PGC-1 alpha are considered “longevity genes.” Dr. Sewell further explains the critical differences between CRISPR, plasmid therapy, and AAV-based gene therapies. He also introduces his new gene therapy for addiction, designed to reduce cravings by up to 90%. Finally, the conversation looks at the future of medicine: how costs will come down, how therapies will expand globally, and how this has the potential to transform health as we know it.#EsraÇavuşoğlu #AyıkKafa #ElevatingLifeEvolvingHealth #Longevilab#DrPatrickSewell #LongevityDr. Patrick E. Sewell, MD:Website: https://www.triplehelixscience.com/ *Collaborations & Sponsors:https://dotshub.com/ Special thanks to T.C. Istanbul Gedik Universityhttps://www.gedik.edu.tr/en/ 00:00-7:31 Introduction. Introducing Dr. Patrick Sewell.7:31-10:14 What is Gene Therapy?10:14-13:11 Fighting cancer with gene therapy13:11-20:51 Why time is the enemy in cancer20:51-29:48 Longevity & Aging Genes29:48-33:01 Cognitive Decline & Dementia33:01-41:10 Folistatin & Muscle Health41:10-44:14 Performance enhancement44:14-47:11 Rare Diseases & Personalized Medicine47:11-51:55 Global Gene Therapy Projects51:55-57:57 Treatment process57:57-1:00:57 Addiction Gene Therapy1:00:57-1:04:07 Wrap up. *To subscribe to our channel* https://www.youtube.com/@ayikkafa *Dr. Esra Çavuşoğlu, PhD*Instagram: https://www.instagram.com/esracavusoglu/ https://www.instagram.com/longevilab Web: https://www.longevilab.com/hakkimizda#esra-cavusoglu *To Reach Us * [email protected]*About Ayık Kafa*Dr. Esra Çavuşoğlu, PhD, took her studies, starting from her personal treatmentexperiences and continuing with her clinical psychology education, to the nextlevel by completing her PhD focused on Addiction. Dr. Esra in Ayık Kafapodcast discusses the world’s latest technologies, protocols, products and research in the fields of Biohacking and Longevity, while sharing first-handinformation and experiences about the Disease of Addiction, as well as herlatest academic studies.*About Dr. Esra Çavuşoğlu, PhD*Longevilab’s founder, Dr. Esra, is a United States and internationally trainedclinical psychologist and a certified addiction therapist in New York. She servedas International Development Advisor on the Yale University Faculty ofMedicine Clinical Advisory Board. She is the founder and supervisor ofGaziantep Oya Bahadır Yüksel Rehabilitation Center, Dr. Esra is the designerand implementer of the Turkey Rehabilitation Model. Dr. Esra founded theContemporary Addiction Studies Association (ÇABAÇAD) in order to combatTurkey’s growing addiction problem.

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