A Stent That Disappears
Got something to say to this podcast? Send a voicemail, and you might hear yourself on the next episode! Episode 158 of the Professor Alex Volinsky podcast. A Zn-0.8Cu biodegradable stent in porcine coronary arteries held structure 6 months, disintegrated after 9, endothelialized within a month, and left ~28% of its volume at 2 years — no thrombosis or inflammation, degradation products clearing into the vessel wall. Neutrally framed: preclinical large-animal study, not human clinical data. Based on the paper: Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery; Chao Zhou et al. (28 authors, incl. A.A. Volinsky); Acta Biomaterialia, 2019, Vol. 97, pp. 657–670. Hosts Elena and Marcus. AI-generated voices.
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