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Antidiabetiker oder Longevity Drugs? Sind Diabetes Medikamente Geroprotektiv? episode artwork

EPISODE · Aug 27, 2025 · 1H

Antidiabetiker oder Longevity Drugs? Sind Diabetes Medikamente Geroprotektiv?

from Longevity Decoded · host Ben Knop, Jan Holzhacker

Antidiabetika als Longevity-Drugs: Hype oder echte Geroprotektion? In Folge 26 und dem Teil 3 des Metabolischen Syndroms -ordnen wir die Evidenz zu Metformin, SGLT2-Inhibitoren und GLP-1-Agonisten nüchtern ein – jenseits von Schlagzeilen und reinem Gewichtsverlust-Effekt. Wir sprechen über Mechanismen, gemischte Tier- und Human­daten, kardiovaskuläre Endpunkte und offene Fragen für Gesunde.Was dich erwartet:Was kardiometabolische Endpunkte wirklich über Langlebigkeit aussagenMechanismen: Insulin/IGF-1, AMPK/mTOR, Entzündung, Parallelen zur KalorienrestriktionMetformin: Datenlage, mögliche B12-Probleme, Einfluss auf TrainingsanpassungenSGLT2: Herz-/Nierenschutz, ITP-Mausdaten, typische RisikenGLP-1: Ergebnisse aus großen Studien, was nach Absetzen passiert, mögliche Sarkopenie-RisikenPraxis: Für wen was sinnvoll sein könnte, Monitoring, Training und Protein als BasisWenn ihr euch in Zukunft mehr derartige Themen wünscht oder wir auf bestimmte Medikamente genauer eingehen sollen, schreibt es in die Kommentare !

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Antidiabetiker oder Longevity Drugs? Sind Diabetes Medikamente Geroprotektiv?

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