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Approaches to Alzheimer's episode artwork

Apr 13, 2024 5 min

Approaches to Alzheimer's

from BioTech Breakdown Hosted by BioTechPassion

Join me as we dive into the mechanism behind Alzheimer's disease and different approaches in development to treat this condition! Sources: 1) DZNE Abt. fuer Presse- und Oeffentlichkeitsarbeit. “Tau.” DZNE, www.dzne.de/en/news/background/tau/. Accessed 13 Apr. 2024. 2) E;, Wegmann S;Biernat J;Mandelkow. “A Current View on Tau Protein Phosphorylation in Alzheimer’s Disease.” Current Opinion in Neurobiology, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/33892381/#:~:text=Elevated%20phosphorylation%20and%20aggregation%20of,modifications%20in%20the%20disease%20context. Accessed 13 Apr. 2024. 3) Schubert, Charlotte. “Family of protein fragments promises fresh view of alzheimer’s disease.” Proceedings of the National Academy of Sciences, vol. 116, no. 23, 4 June 2019, pp. 11082–11084, https://doi.org/10.1073/pnas.1905886116. 4) Zheng, Hui, and Edward H Koo. “The Amyloid Precursor Protein: Beyond Amyloid - Molecular Neurodegeneration.” BioMed Central, BioMed Central, 3 July 2006, molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-1-5. 5) Person. “What Is Anti-Amyloid Therapy for Alzheimer’s Disease?” Nebraska Medicine Omaha, NE, Nebraska Medicine, 1 June 2023, www.nebraskamed.com/health/conditions-and-services/what-is-anti-amyloid-therapy-for-alzheimers-disease. 6) “Anti-Amyloid Therapies for Alzheimer’s Disease.” WebMD, WebMD, www.webmd.com/alzheimers/anti-amyloid-therapies-alzheimers. Accessed 13 Apr. 2024. 7) Menting, Kelly Willemijn, and Jurgen A H R Claassen. “Β-Secretase Inhibitor; a Promising Novel Therapeutic Drug in Alzheimer’s Disease.” Frontiers in Aging Neuroscience, U.S. National Library of Medicine, 21 July 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4104928/. 8) Mullard, Asher. “BACE Failures Lower Ad Expectations, Again.” Nature News, Nature Publishing Group, 30 May 2018, www.nature.com/articles/nrd.2018.94. 9) M, Arbel, et al. “Give BACE Inhibitors a Second Chance?” ALZFORUM, www.alzforum.org/news/conference-coverage/give-bace-inhibitors-second-chance. Accessed 13 Apr. 2024.

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