Are auctions worth it?

My parents moved out of New York last year and needed to get rid of a bunch of old stuff that they had accumulated over the years. I offered to sell some of the nicer stuff in exchange for a small commission (a girl's gotta make cash during covid somehow.) I sold a rug for them two months ago which was pretty easy but had no idea how complicated it would be to sell an original Peanuts cartoon that they had for some reason.