Autophagy, Mitochondrial Health, & Lifespan Optimization | Leslie Kenny | Ep. 318 episode artwork

EPISODE · Nov 9, 2025 · 1H 14M

Autophagy, Mitochondrial Health, & Lifespan Optimization | Leslie Kenny | Ep. 318

from The Aging Well Podcast · host Jeff Armstrong

In this episode of ‘The Aging Well Podcast’, Dr. Jeff Armstrong is joined by Leslie Kenny—Harvard graduate, Oxford Longevity Project founder, and self-described “age rebel.” At 60 years old, Leslie has achieved a biological age of 21—and she’s on a mission to help others do the same.From reversing autoimmune disease to mastering mitochondrial health, Leslie breaks down the science of aging in a way that’s both inspiring and deeply practical. Learn how shifts in immunity, cellular cleanup (autophagy), and lifestyle decisions can help you stay sharp, energized, and resilient—especially after 40.If you’re ready to take control of how you age, this episode offers the tools, science, and encouragement to help you live better, longer.Learn more about Leslie Kenny and the Oxford Longevity Project at: https://oxfordlongevityproject.org/Please, support The Aging Well Podcast by hitting the ‘like’ button, subscribing/following the podcast, sharing with a friend, and….BUY the products you need to… age well from our trusted affiliates and support the mission of The Aging Well Podcast*.Oxford Healthspan | Primeadine®, a plant-derived spermidine supplement | 10% off code: AGINGWELL | ⁠https://www.oxfordhealthspan.com/AGINGWELL⁠The Aging Well Podcast merchandise | Show how you are aging well | Use the promo code AGING WELL for free shipping on orders over $75 | https://theagingwellpodcast-shop.fourthwall.com/promo/AGINGWELLAuro Wellness | Glutaryl—Antioxidant spray that delivers high doses of glutathione (“Master Antioxidant”) | 10% off Code: AGINGWELL at https://aurowellness.com/agingwellpodcastRebalance Health | products created by hormone health experts to lower cortisol, improve sleep, and minimize the impact of stress on the body and mind | https://rebalancehealth.com with the promo code: AGING WELLJigsaw Health | Trusted supplements. “It’s fun to feel good.” | Click the following link for 10% off: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Prolon | The Fasting Mimicking Diet (FMD) is a revolutionary five-day nutrition program scientifically formulated to mimic the effects of a prolonged water fast while still allowing nourishment - supporting the benefits of fasting without the challenges and risks that come from water-only fasts. | For the best available discount always use this link: https://prolonlife.com/theagingwellpodcastL-Nutra Health | The medical division of L-Nutra, focused on helping people manage and potentially reverse chronic health conditions, like type 2 diabetes, prediabetes, insulin resistance, and obesity, using personalized, lifestyle-based programs grounded in evidence, not prescriptions. | Use this link: https://l-nutrahealth.com/theagingwellpodcastFusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | 15% off Code: AGINGWELL | https://fusionaryformulas.com/Dr Lewis Nutrition | Fight neurodegeneration and cognitive decline with Daily Brain Care by Dr Lewis Nutrition—a proven daily formula designed to protect and restore brain function. | 10% off code: AGINGWELL or use the link: https://drlewisnutrition.com/AGINGWELLThrive25 | Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffreyTruDiagnostic | Your source for epigenetic testing | 12% off Code: AGEWELL or use the link: https://shop.trudiagnostic.com/discount/AGEWELL*We receive commission on these purchases. Thank you.4

In this episode of ‘The Aging Well Podcast’, Dr. Jeff Armstrong is joined by Leslie Kenny—Harvard graduate, Oxford Longevity Project founder, and self-described “age rebel.” At 60 years old, Leslie has achieved a biological age of 21—and she’s on a mission to help others do the same.From reversing autoimmune disease to mastering mitochondrial health, Leslie breaks down the science of aging in a way that’s both inspiring and deeply practical. Learn how shifts in immunity, cellular cleanup (autophagy), and lifestyle decisions can help you stay sharp, energized, and resilient—especially after 40.If you’re ready to take control of how you age, this episode offers the tools, science, and encouragement to help you live better, longer.Learn more about Leslie Kenny and the Oxford Longevity Project at: https://oxfordlongevityproject.org/Please, support The Aging Well Podcast by hitting the ‘like’ button, subscribing/following the podcast, sharing with a friend, and….BUY the products you need to… age well from our trusted affiliates and support the mission of The Aging Well Podcast*.Oxford Healthspan | Primeadine®, a plant-derived spermidine supplement | 10% off code: AGINGWELL | ⁠https://www.oxfordhealthspan.com/AGINGWELL⁠The Aging Well Podcast merchandise | Show how you are aging well | Use the promo code AGING WELL for free shipping on orders over $75 | https://theagingwellpodcast-shop.fourthwall.com/promo/AGINGWELLAuro Wellness | Glutaryl—Antioxidant spray that delivers high doses of glutathione (“Master Antioxidant”) | 10% off Code: AGINGWELL at https://aurowellness.com/agingwellpodcastRebalance Health | products created by hormone health experts to lower cortisol, improve sleep, and minimize the impact of stress on the body and mind | https://rebalancehealth.com with the promo code: AGING WELLJigsaw Health | Trusted supplements. “It’s fun to feel good.” | Click the following link for 10% off: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Prolon | The Fasting Mimicking Diet (FMD) is a revolutionary five-day nutrition program scientifically formulated to mimic the effects of a prolonged water fast while still allowing nourishment - supporting the benefits of fasting without the challenges and risks that come from water-only fasts. | For the best available discount always use this link: https://prolonlife.com/theagingwellpodcastL-Nutra Health | The medical division of L-Nutra, focused on helping people manage and potentially reverse chronic health conditions, like type 2 diabetes, prediabetes, insulin resistance, and obesity, using personalized, lifestyle-based programs grounded in evidence, not prescriptions. | Use this link: https://l-nutrahealth.com/theagingwellpodcastFusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | 15% off Code: AGINGWELL | https://fusionaryformulas.com/Dr Lewis Nutrition | Fight neurodegeneration and cognitive decline with Daily Brain Care by Dr Lewis Nutrition—a proven daily formula designed to protect and restore brain function. | 10% off code: AGINGWELL or use the link: https://drlewisnutrition.com/AGINGWELLThrive25 | Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffreyTruDiagnostic | Your source for epigenetic testing | 12% off Code: AGEWELL or use the link: https://shop.trudiagnostic.com/discount/AGEWELL*We receive commission on these purchases. Thank you.4

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Autophagy, Mitochondrial Health, & Lifespan Optimization | Leslie Kenny | Ep. 318

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This episode was published on November 9, 2025.

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In this episode of ‘The Aging Well Podcast’, Dr. Jeff Armstrong is joined by Leslie Kenny—Harvard graduate, Oxford Longevity Project founder, and self-described “age rebel.” At 60 years old, Leslie has achieved a biological age of 21—and she’s on a...

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