Backtable Brief: Sedation and Anesthesia in Bone Cancer Ablation with Dr. Damian Dupuy

From anesthesia decisions to ablation strategy, what really separates a good outcome from a great one in bone tumor ablation? This BackTable MSK Brief features an enlightening conversation between host Kavi Krishnasamy and bone ablation pioneer Dr. Damian Dupuy. They cover anesthesia choices for different patient scenarios, optimal procedural techniques and agent selection for bone ablations, and the combination of local and systemic therapies for oligometastatic and oligo-progressive diseases. The doctors also tackle myths and realities around thermal and cryoablation, examining both clinical trial data and real-world experiences.  Episode Outline 00:00 - Introduction 00:40 - Selecting General Anesthesia vs. MAC 03:30 - Approach to Multiple Bony Lesions in Metastatic Disease 07:27 - Ablation Confirmation and Techniques Utilized in Bone Ablation  09:00 - Research Insights Surrounding RFA in Bone 12:16 - Sclerotic vs. Lytic Lesions: Techniques and Considerations 14:47 - Skin Protection During Superficial Lesion Treatments 16:38 - Analyzing Clinical Trials: Motion and OPuS One 20:51 - Conclusion Resources Dr. Damian E. Dupuy, MD, FACR https://www.linkedin.com/in/damian-e-dupuy-md-facr-6b080b1b/  Radiofrequency Ablation Provides Rapid and Durable Pain Relief for the Palliative Treatment of Lytic Bone Metastases Independent of Radiation Therapy: Final Results from the OsteoCool Tumor Ablation Post-Market Study https://pmc.ncbi.nlm.nih.gov/articles/PMC10156864/  Cryoablation for Palliation of Painful Bone Metastases: The MOTION Multicenter Study https://pmc.ncbi.nlm.nih.gov/articles/PMC8011449/