Before You Start Ozempic l A deep dive into GLP-1 biology, Semaglutide vs Calocurb, Natural appetite suppression, PMS, and Female Metabolic Health with Sarah Kennedy episode artwork

EPISODE · Feb 9, 2026 · 58 MIN

Before You Start Ozempic l A deep dive into GLP-1 biology, Semaglutide vs Calocurb, Natural appetite suppression, PMS, and Female Metabolic Health with Sarah Kennedy

from Renee Belz & Lauren Sambataro · host Biohacker Babes

In this episode, we sit down with Sarah Kennedy, Founder and CEO of Calocurb, to explore a radically different approach to appetite control rooted in real science, not willpower. With decades of leadership in nutrition and food science, Sarah breaks down how GLP-1s work, the downsides of chronic calorie restriction, and the key differences between synthetic drugs like semaglutide and natural GLP-1 stimulation. We dive into the history of bitters, digestion, and how Calocurb’s patented ingredient Amarasate® supports appetite regulation through the gut–brain axis. Sarah also shares compelling clinical trial results, insights on coming off GLP-1 drugs, and why under-eating—especially for women—can backfire hormonally. It’s a nuanced, empowering conversation about working with your biology to feel satisfied, nourished, and in control.Founder and CEO of Calocurb, Sarah Kennedy shepherded years of scientific research and clinical trials to bring a revolutionary product to market. A veterinarian by training, with more than 20 years’ experience in dietary and animal nutrition, Sarah has held a number of CEO and senior executive positions in food and agriculture industries, at companies including Fonterra and Healtheries/Vitaco NZ.  In 2010, at MIT, Sarah completed a Sloan Fellowship Program in Global Leadership and Innovation and has spent decades leading in health, nutrition and consumer products with executive roles at many, many companies.Calocurb is a 100% natural appetite control supplement. Amarasate®, the patented active ingredient in Calocurb, was developed in New Zealand over 14 years and with $30m invested by Plant and Food Research, the largest NZ government-owned research institute.SHOW NOTES:0:40 Welcome to the show!2:39 About Sarah Kennedy3:54 Welcome her to the podcast!5:04 What is a GLP-1?7:27 Downside of calorie restriction8:52 Natural vs synthetic GLP-113:41 Coming off of GLP-1s14:56 Why it isn’t just willpower18:07 History of bitters in the diet20:12 Stimulating digestion & appetite suppression23:22 Calocurb Study26:02 Semaglutide vs Calocurb29:45 Clinical trial results32:54 Calocurb & PMS34:10 Dosing Calocurb40:08 Our personal experiences43:37 Importance of protein intake46:41 Females that are under-eating54:52 Where to find Sarah & Calocurb55:30 Her final piece of advice57:21 Thanks for tuning in!RESOURCES:Website: www.Calocurb.com - Discount code: RENEE10IG: CalocurbFacebook: CalocurbGLOBALSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

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Before You Start Ozempic l A deep dive into GLP-1 biology, Semaglutide vs Calocurb, Natural appetite suppression, PMS, and Female Metabolic Health with Sarah Kennedy

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