EPISODE · Aug 25, 2025 · 49 MIN
Biomarkers in MS (NfL, GFAP, Kappa Light Chains): when they actually change decisions?
from BeewellwithMS podcast by Dr Agne Straukiene · host Dr Agne Straukiene
Welcome to another episode of the BeeWellwithMS Podcast, hosted by Dr. Agne Straukiene. This special episode delves into the world of biomarkers in multiple sclerosis (MS). Learn about the silent signals inside our bodies that help understand inflammation, disease progression, and responses to treatment even before symptoms occur. Dr. Sharmilee Gnanapavan, a renowned neurologist and expert in biomarker science, joins us to discuss key biomarkers like neurofilament, kappa light chain, GFAP, and more. Whether you are living with MS, a caregiver, or a healthcare provider, this episode offers valuable insights into how these biomarkers can facilitate a more personalised, predictive, and preventative approach to MS care. Stay informed about the latest in MS symptoms, treatment, diet, exercise, and smoldering MS. Don't miss this conversation that's shaping the future of MS care.00:00 Introduction to the Podcast and Today's Topic00:46 Meet Dr. Sharmilee Gnanapavan02:48 Understanding Biomarkers in MS10:24 Kappa Light Chain Free Index Explained16:33 Neurofilament: A Key Biomarker24:42 GFAP and Progressive MS33:26 Emerging Biomarkers: Chitinase-3-like Protein35:31 CXCL13 and B-Cell Activity38:38 Matrix Metalloproteinase-9 (MMP-9)41:28 The Future of Biomarkers in MS47:30 Conclusion and Final ThoughtsBecome a supporter of this podcast: https://www.spreaker.com/podcast/beewellwithms-podcast-by-dr-agne-straukiene--5762905/support.
What this episode covers
Welcome to another episode of the BeeWellwithMS Podcast, hosted by Dr. Agne Straukiene. This special episode delves into the world of biomarkers in multiple sclerosis (MS). Learn about the silent signals inside our bodies that help understand inflammation, disease progression, and responses to treatment even before symptoms occur. Dr. Sharmilee Gnanapavan, a renowned neurologist and expert in biomarker science, joins us to discuss key biomarkers like neurofilament, kappa light chain, GFAP, and more. Whether you are living with MS, a caregiver, or a healthcare provider, this episode offers valuable insights into how these biomarkers can facilitate a more personalised, predictive, and preventative approach to MS care. Stay informed about the latest in MS symptoms, treatment, diet, exercise, and smoldering MS. Don't miss this conversation that's shaping the future of MS care.00:00 Introduction to the Podcast and Today's Topic00:46 Meet Dr. Sharmilee Gnanapavan02:48 Understanding Biomarkers in MS10:24 Kappa Light Chain Free Index Explained16:33 Neurofilament: A Key Biomarker24:42 GFAP and Progressive MS33:26 Emerging Biomarkers: Chitinase-3-like Protein35:31 CXCL13 and B-Cell Activity38:38 Matrix Metalloproteinase-9 (MMP-9)41:28 The Future of Biomarkers in MS47:30 Conclusion and Final ThoughtsBecome a supporter of this podcast: https://www.spreaker.com/podcast/beewellwithms-podcast-by-dr-agne-straukiene--5762905/support.
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Biomarkers in MS (NfL, GFAP, Kappa Light Chains): when they actually change decisions?
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