BLA 180: Choosing the right lipid lowering medication

Welcome back to the trenches! In our final breakdown of the 2026 ACC/AHA lipid guidelines, we are unpacking the pharmacology toolbox. From statins and ezetimibe to PCSK9 inhibitors and the nuances of side effects like SAMS, I want to give you the practical, evidence-informed strategies we need for our patients. We are all just trying to navigate this together. Stop stressing over every health detail & start living! My FREE 'Necessary Nine' PDF cuts through the noise, giving you the essential things you need for a healthy life. ➡️ Download Here: https://www.jrennickemd.com/necessaryninepdf CHAPTERS:00:00 - Intro00:01:00 - Statin Mechanism of Action00:01:34 - Types of Statins and Intensities00:03:04 - Hydrophobic vs Hydrophilic Statins00:05:15 - Statins and Glycemic Control00:06:14 - Pleiotropic Effects of Statins00:07:12 - Statin Side Effects Overview00:08:36 - Ezetimibe as First-Line Add-On00:09:54 - Bempedoic Acid00:11:18 - PCSK9 Inhibitors00:13:16 - Inclisiran and siRNA Therapy00:14:26 - Bile Acid Sequestrants00:15:47 - The Rule of 6 and Combination Therapy00:17:16 - Statin-Associated Muscle Symptoms00:19:04 - CoQ10 Supplementation00:20:07 - Special Populations: Older Adults and Pregnancy00:21:20 - Liver Safety and Drug Interactions00:23:15 - Statins, Dementia, and Brain Fog00:24:23 - Statins and Diabetes Risk00:25:21 - Managing High Triglycerides00:27:06 - Conclusion and Summer Sabbatical SELECTED REFERENCES: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001423 *Disclaimer*This podcast is for entertainment, education, and informational purposes only.The topics discussed should not solely be used to diagnose, treat , or prevent any condition.The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate.Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.