EPISODE · Oct 4, 2011
BME 695L Lecture 6: Normal & Facilitated Cell Entry Mechanisms
from [Audio] BME 695L: Engineering Nanomedical Systems · host James Leary
See references below for related reading.6.1 Introduction6.1.1 the general problem of cell entry6.1.2 choosing modes of cell entry6.1.3 how does Nature do it? (biomimetics)6.2 Non-specific uptake mechanisms6.2.1 pinocytosis by all cells6.2.2 phagocytosis by some cells6.2.3 a recent study of Qdot NP uptake6.3 Nanoparticle uptake6.3.1 NP size matters6.3.2 NP shape matters6.3.3 NP agglomeration reduces uptake6.3.4 A sample study6.4 Receptor-mediated uptake6.4.1 Receptor mediated transport of desired molecules6.4.2 How to study uptake mechanisms by inhibiting pathways with specific drugs6.4.3 Some sample studies6.5 Effects of nanoparticle coatings6.5.1 Acrylate-Facilitated Cellular Uptake6.5.2 Polyethyleneimine Coating Enhancement of Cellular Uptake6.6 Effects of microenvironment and external stimuli
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