Busting Tauopathies (Season 4: Episode 16)

Get ready for DNA mutation rates across the generations, a potential Alzheimer’s ‘vaccine’, tissue-expansion mass-spectrometry, updating old methods in SAS, planning a statistical analysis, and seven new Cancer Grand Challenges. Science On.References:Human de novo mutation rates from a four-generation pedigree referenceTargeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaquesTEMI: tissue-expansion mass-spectrometry imagingUpdating old SAS programs: A case study with PROC LOESSStrategies for Choosing and Planning a Statistical AnalysisUSAMRAA: Alzheimer’s Research Program Transforming Research AwardCancer Grand ChallengesR Packages:circlizePlus: Using 'ggplot2' Feature to Write Readable R Code for Circular Visualizationglmfitmiss: Fitting GLMs with Missing Data in Both Responses and Covariates