Science Research Weekly

Welcome to Science Research Weekly, Season 5, Episode 15, Expand Your Scientific Scope. Get ready for algal microplastics remediation, cosmic large-scale structure, coffee and dementia risk, tales of outer membrane vesicles and tumor microenvironment subtypes, why a high R-squared can be misleading, and the MIRA award from the NIH. Science On.References:Remediation and upcycling of microplastics by algae with wastewater nutrient removal and bioproduction potentialLarge-scale Structure in COSMOS-Web: Tracing Galaxy Evolution in the Cosmic Web up to z ∼ 7 with the Largest JWST SurveyCoffee and Tea Intake, Dementia Risk, and Cognitive FunctionLoad Identification in Bistable Spacecraft Boomsvia Parametric Data-Driven Modeling"Like Taking the Path of Least Resistance": Exploring the Impact of LLM Interaction on the Creative Process of ProgrammingDiscovery and characterisation of OMVs produced by the bee gut microbiotaTumorArchetypeR: A modular framework to derivesignature-based tumor subtypesLearning Data Science: Why a High R^2 Can Be MisleadingMaximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)R Packages: marsruntime: Portable Mars Runtime ReplayQsRutils: R Functions Useful for Community EcologyROCsurvcomp: ROC-Based Methods for Comparing Survival Distributions with Right, Left, and Doubly Censored Datawarmthcompetence: Warmth and Competence Detectors

Welcome to Science Research Weekly, Season 5, Episode 14, Get ready for chemical synthesis a la LMMs, an amino acid for Alzheimer’s pathology suppression, a trans-Neptunian object with an atmosphere, PhysForge vs. ProtSpace, and cancer grants from the Department of War.References:Chemical reasoning in LLMs unlocks strategy-aware synthesis planning and reaction mechanism elucidationOral administration of arginine suppresses Aβ pathology in animal models of Alzheimer's diseaseMultiple independent genetic code reassignments of the UAG stop codon in phyllopharyngean ciliatesDetection of an atmosphere on a trans-Neptunian object beyond PlutoBioprinting of Microtissues Within Mechanically Tunable Support Baths to Engineer Anisotropic Musculoskeletal TissuesPhysForge: Generating Physics-Grounded 3D Assets for Interactive Virtual WorldProtSpace: Protein Universe in Your BrowserDoW Peer Reviewed Cancer, Idea AwardBioengineering Research Grants

Welcome to Science Research Weekly, Season 5, Episode 13, Attack of the 50-foot Octopus! Get ready for giant predatory Cretaceous octopuses, ice-water clouds on a distant Jupiter, anti-viral acrylic surfaces, 3D printing inside living cells, March’s top 40 new CRAN packages, and a grant on Engineering Biological and Biomedical Systems. Science On.References:Compositional selection of phospholipid compartments in icy environments drives the enrichment of encapsulated genetic informationEarliest octopuses were giant top predators in Cretaceous oceansA Second Visit to Eps Ind Ab with JWST: New Photometry Confirms Ammonia and Suggests Thick Clouds in the Exoplanet Atmosphere of the Closest Super-JupiterDesigning Scalable Mechano-Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral InactivationRemoval of Microplastics from Drinking Water by Moringa oleifera Seed: Comparative Performance with Alum in Direct and in-Line Filtration SystemsTwo-Photon 3D Printing of Functional Microstructures Inside Living CellsCAN WE TEACH GENERATIVE ARTIFICIAL INTELLIGENCE THE DESIGNLANGUAGE OF ENGINEERED LIVING MATERIALS? Harnessing AI to Build Virtual CellsUrban soil microbiomes exhibit taxonomic and functional potential for enhanced contaminant cyclingR 4.6.0 is releasedMarch 2026 Top 40 New CRAN PackagesLittle useless-useful R functions – Desk plant simulatorDesign your plots (ggplot) for mobileEngineering Biological and Biomedical Systems (EBBS)INSPIRING GENERATIONS OF NEW INNOVATORS TO IMPACT TECHNOLOGIES IN ENERGY 2026 (IGNIITE 2026)John Templeton Foundation - Life SciencesR Packages: rPandas: Translating from R to Python's Pandas Package

Welcome to Science Research Weekly, Season 5, Episode 12, Dropping the PepHammer. Get ready for ancient soft sponges, astronomical biosignature spotting via grouped planets, the Epidemiology of AI, crop management via smartphone, an examination of NIH funding outputs, dropping the PepHammer, asking if AI agents save time for scientists, and a grant on specialty crops. Science On.References:A late-Ediacaran crown-group sponge animalPearling drives mitochondrial DNA nucleoid distributionp21+TREM2+ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver diseaseAn Agnostic Biosignature Based on Modeling Panspermia and TerraformingVisplot: A visibility plot and observation scheduling tool forastronomical observatoriesAI-assisted writing and the reorganization of scientific knowledgeThe Epidemiology of Artificial IntelligenceThe Common Fund Data Ecosystem (CFDE) Image-based leaf SPAD value and chlorophyll measurement using a mobilephone: enabling accessible and sustainable crop managementComparing the outputs of intramural and extramural grants funded by National Institutes of Health PepHammer – a lightweight web-based tool for bioactive peptide matching and identification My Domain: proteome-wide scanning of TMDsWhy Most Time Series Models Fail Before They StartDo AI coding agents save scientists time?Using R to Teach R: Lessons for Software DevelopmentSpecialty Crop Research InitiativeWhat is a Specialty Crop?Translational Medicine Postdoctoral FellowshipScience Café Mini-GrantR Packages:glm4: Fitting Generalized Linear Models Using Sparse Matricestinyrox: Minimal R Documentation Generatorbaseverse: Modern Base-R Functionstidyfun: Tidy Functional Data Wrangling and Visualization

Welcome to Science Research Weekly, Season 5, Episode 11. Get ready for Vitamin D and dementia-protection, exploding black holes, semi-autonomous robots for Martian exploration, a forbidden planet, a pristine star, Mothbox and Mothbot, One-pass statistical formulas in SAS, and building your own programming language. Science On.References:Association of Circulating Vitamin D in Midlife With Increased Tau-PET Burden in Dementia-Free AdultsDNA–drug conjugates enable logic-gated drug delivery amplified by hybridization chain reactionsExplaining the PeV Neutrino Fluxes at KM3NeT and IceCube with Quasiextremal Primordial Black HolesSemi-autonomous exploration of martian and lunar analogues with a legged robot using a Raman-equipped robotic arm and microscopic imagerGEMS JWST: Transmission Spectroscopy of TOI-5205b Reveals Significant Stellar Contamination and a Metal-poor AtmosphereA nearly pristine star from the Large Magellanic CloudSloan Digital Sky SurveyEctopic NMDAR expression in cancer unmasks germline-encoded autoimmunityRoSHI: A Versatile Robot-oriented Suit for Human Data In-the-WildClickGuard: A Trustworthy Adaptive Fusion Framework for Clickbait DetectionMothbox and Mothbot: automated light trap and data processing system for scalable insect monitoringPatterns of host plant use by monarch butterflies revealed through annotation of more than 35,000 community science recordsiNaturalistOne-pass formulas for mean and varianceHold On Hope: publication lag times at cell biology journalsCollaborating between Bioconductor and R-universe on Development of Common InfrastructureR-UniverseYou can just build your own programming languageT — The Orchestration Engine for Polyglot Data ScienceR Packages:aggreCAT: Mathematically Aggregating Expert Judgmentsravel: AI Copilot for R Analysis Workflows in 'RStudio'

Welcome to Science Research Weekly, Season 5, Episode 10, Call me Isoptera. Get ready for fusion plasma corrections, Alzheimer’s and meat consumption, cytoplasmic tradewinds, a new termite that looks like Moby Dick, immersive dreaming and restfulness, the Artemis II Crew launch, why learning R in 2026 is a good career move, and the top 40 new CRAN packages for February 2026. Science On. References:Combined Influence of Rotation and Scrape-Off Layer Drifts on Recycling Asymmetries in Tokamak PlasmasMeat Consumption and Cognitive Health by APOE GenotypeThe landscape of microbial associations in human cancerCompartmentalized cytoplasmic tradewinds direct soluble proteinsAvoiding and reducing microplastic false positives from dry glove contactCryptotermes mobydicki (Isoptera, Kalotermitidae), an extraordinary new termite species from French GuianaRapid mid-Cretaceous diversification of squid and cuttlefish preceded radiation into coastal nichesImmersive NREM2 dreaming preserves subjective sleep depth against declining sleep pressureA chelicera-bearing arthropod reveals the Cambrian origin of cheliceratesNASA’s Artemis II Crew Launches to the MoonHow much information is there for inferringspecies trees?Microdiversity is higher in temperate than in virulentbacteriophages from soil environmentsBaktfold: Sensitive protein functional annotation acrossthe microbial tree of life using structural informationMeet dataviewR: The View() You Always WantedWhy Learning R is a Good Career Move in 2026February 2026 Top 40 New CRAN Packages R Packages:Taxdiv: Taxonomic Diversity Indices Using Deng EntropyGgrefine: Pretty 'ggplot2' ThemesHexsession: Create a Tile of Logos for Loaded PackagesInsectLabelR: Create Labels for Insect in Collection

Hello and welcome to Science Research Weekly. Get ready for the dangers of cold weather on cardiovascular health, new amphipods aplenty, a list of habitable rocky exoplanet, pico-satellite concepts, mitochondrial flickers, toxin-antidotesystems in vertebrates, and using science to find the best decaf coffee. Science On.References: Cardiovascular disease mortality attributable to monthly non-optimal temperature in the united states: a county-level analysisNew deep-sea Amphipoda from the Clarion-Clipperton Zone: 24 new species described under the Sustainable Seabed Knowledge Initiative: One Thousand Reasons campaignBiodiversity boost: 24 new deep-sea species discovered in major Pacific researchProbing the limits of habitability: a catalogue of rocky exoplanets in the habitable zoneText embedding models yield detailed conceptual knowledge maps derived from short multiple-choice quizzesThousands of pico-satellites may transform how phones connect to spaceDynamical Systems in Cosmology: Reviewing An Alternative ApproachMassive star clusters detected by JWST as natural birth places to form intermediate-mass black holesBeyond Pulsing Dyes: Are Flickers the Language of the MitochondrialNetwork? The morphotype approach to classification of aerial animals in radar data A Vertebrate Toxin-Antidote System That Sabotages Mouse EmbryogenesisDigital Biology with R: Advanced Bioinformatics, Predictive Modeling, and Time Series Analysis for Modern Life ScienceUsing science to find the best decafR Packages:Ixsurface: Interactive 3D Surface Plots for Multi-Factor Interaction Visualizationlongitree: Decision Tree Analysis for Longitudinal Measurement DataggforestplotR: Publication-Ready Forest Plots with 'ggplot2'ksformat: 'SAS'-Style 'PROC FORMAT' for Rstopmotion: Build Stop Motion Animations from Image Sequencessubtools: Read and Manipulate Video Subtitlestaxodist: Taxonomic Distance and Phylogenetic Lineage ComputationCardiovascular diseasemortality attributable to monthly non-optimal temperature in the united states:a county-level analysisNew deep-sea Amphipodafrom the Clarion-Clipperton Zone: 24 new species described under theSustainable Seabed Knowledge Initiative: One Thousand Reasons campaignBiodiversity boost: 24new deep-sea species discovered in major Pacific researchProbing the limits ofhabitability: a catalogue of rocky exoplanets in the habitable zoneText embedding modelsyield detailed conceptual knowledge maps derived from short multiple-choicequizzesThousands ofpico-satellites may transform how phones connect to spaceDynamical Systems inCosmology: Reviewing An Alternative ApproachMassive star clustersdetected by JWST as natural birth places to form intermediate-mass black holesBeyond Pulsing Dyes: AreFlickers the Language of the MitochondrialNetwork? The morphotype approachto classification of aerial animals in radar data A VertebrateToxin-Antidote System That Sabotages Mouse EmbryogenesisDigital Biology with R:Advanced Bioinformatics, Predictive Modeling, and Time Series Analysis forModern Life ScienceUsing science to findthe best decaf

Welcome to Science Research Weekly, Season 5, Episode 8, Cellular Senses and Psyche’s Interior. Get ready for cellular mechanosensing, modeling the interior structure of Psyche, microbial succession in soil restoration, and Bayesian Linear regression in R. Science On.References:Emergent depth-mechanosensing of epithelial collectives regulates cell clustering and dispersal on layered matricesExploring the Interior Structure of (16) Psyche Through Basin-Scale CollisionsOrganic, Transparent, and Flexible Films Exhibiting White-Light Emission via Polymer-Network Engineering: A Non-Dye-Centric StrategyGenome-wide discovery of cis-regulatory elements in a large genomeTaxonomic filtering accompanies functional expansion during long-term soil restorationMicroscale spatial fragmentation promotes bacterial survival underantibioticsBayesian Linear Regression in R: A Step-by-Step TutorialR Packages:SCIproj: Creates a Scientific Project Skeleton as an R PackageCausalplot: Create Publication-Ready Causal DiagramsScimetr: Analysis of Scientific Publication Data with R

Hello and welcome to Science Research Weekly, Season 5, Episode 7. Get ready for 3D ants via synchrotron, recycled aluminum alloys, chickpeas in lunar regolith, planet collisions, World Mouse, R version "Reassured Reassurer", estimating pi by tossing coins, and a grant on reducing housing hazards. Science On.References:High-throughput phenomics of global ant biodiversityNew ORNL aluminum alloy to strengthen domestic auto supply chainBioremediation of lunar regolith simulant through mycorrhizal fungi and plant symbioses enables chickpea to seedGaia-GIC-1: An Evolving Catastrophic Planetesimal Collision CandidateThe 3D architecture of the ctenophore aboral organ and the evolution of complex integrative centers in animalsCryptic species are widespread across vertebratesSearching for Magnetic White Dwarfs in LAMOST DR10World Mouse: Exploring Interactions with a Cross-Reality CursorHunting for microsatellite instability in long-read data with Owl R 4.5.3 is releasedEstimate pi by tossing coinsHousing-Related Hazards and Lead-Based Paint Capital Fund ProgramR Packages:wstats: Weighted Descriptive Statisticsggwidth: Standardise 'ggplot2' Geom WidthAV1R: 'AV1' Video Encoding for Biological Microscopy Data

Welcome to Science Research Weekly, Season 5, Episode 6. Get ready for quorum sensing for bacterial engineering, an antibiotic-resistant microbe on ice, a new scimitar-crested spinosaurid, planetesimal snowmen, sheepox viral evolution, the fate of horizontally acquired genes, the R Journal Volume 17/4, and a grant for Feed the Future innovation labs. Science On.References:Revision of the trematosaurid Erythrobatrachus noonkanbahensis confirms a cryptic marine temnospondyl community from the Lower Triassic of Western AustraliaConstruction and Functional Characterization of a Heterologous Quorum Sensing Circuit in Clostridium sporogenesFirst genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activitiesScimitar-crested Spinosaurus species from the Sahara caps stepwise spinosaurid radiationDirect contact binary planetesimal formation from gravitational collapseOxygen metabolism in descendants of the archaeal-eukaryotic ancestorExocometary physics: material release and tailsSearches for new physics beyond the Standard Model in hyperon sector3,500 years of sheeppox virus evolution inferred from archaeological and codicological genomesThe fate of horizontally acquired genes: rapid initial turnover followed by long-term persistenceThe R Journal: Volume 17/4Comparing flavor characteristics of Scotch whiskies: A principal component analysisLittle useless-useful R functions – Typing speed benchmarkPathways to Enable Secure Open-Source EcosystemsFeed the Future Innovation LabsR Packages:bigMICE: Multiple Imputation of Big Databracketeer: Tournament Generatorphymapnet: Phylogeny-Guided Bayesian Microbial Network InferencetReeTraits: Calculate Tree Traits from Terrestrial Lidarort: Create a Data Frame Representation of an Imagetinyimg: Optimize and Compress Images

Hello and welcome to Science Research Weekly, Season 5, Episode 5, Oops, All Singularities! Get ready for tiny nanopores, a supernova-skipping black hole, kidney disease ultrasounds by robot, and keeping files organized for publication. Science On.References:https://www.nature.com/articles/s41467-026-68800-xhttps://www.science.org/doi/10.1126/science.adt4853https://arxiv.org/pdf/2602.16673https://arxiv.org/pdf/2602.16641https://www.biorxiv.org/content/10.64898/2026.02.16.706223v2https://www.biorxiv.org/content/10.1101/2024.12.24.629435v2https://www.biorxiv.org/content/10.64898/2025.12.11.693795v2https://www.r-bloggers.com/2026/02/keeping-files-organised-for-publication/R Packages:Framework: Structured Data ScienceProject ScaffoldinggsDesignNB: Sample Size andSimulation for Negative Binomial OutcomesSimtablR: Easy Publication-ReadyTables and Regression AnalysisScholid: Tools for Scholarly andAcademic IdentifiersR Packages:Framework: Structured Data Science Project ScaffoldinggsDesignNB: Sample Size and Simulation for Negative Binomial OutcomesSimtablR: Easy Publication-Ready Tables and Regression AnalysisScholid: Tools for Scholarly and Academic IdentifiersReferences:Chemistry-drivenautonomous nanopore membranesDisappearanceof a massive star in the Andromeda Galaxy due to formation of a black holeNeighborhoodStability as a Measure of Nearest Neighbor SearchabilityTowardsAutonomous Robotic Kidney Ultrasound: Spatial-Efficient Volumetric Imaging viaTemplate Guided Optimal PivotingDifferentialanalysis of genomics count data with edge*Virus-freecontinuous directed evolution in human cells using somatic hypermutationTranscriptionalActivation of Estrogen Receptor-alpha and Estrogen Receptor-beta from ElephantShark (Callorhynchus milii)Keeping files organised forpublication R Packages:Framework: Structured Data ScienceProject ScaffoldinggsDesignNB: Sample Size andSimulation for Negative Binomial OutcomesSimtablR: Easy Publication-ReadyTables and Regression AnalysisScholid: Tools for Scholarly and AcademicIdentifiers

Welcome to Science Research Weekly, Season 5, Episode 4, And the Crowd Goes Wild for Chitons. Get ready for genes before the last common ancestor, a new Cold Earth, herbivorous microsaurs, lava tubes on Venus, a publicly-named chiton species, paleontology R packages, and the Protean grant from DARPA. Science On.References:Universal paralogs provide a window into evolution before the last universal common ancestorA Cool Earth-sized Planet Candidate Transiting a Tenth Magnitude K-dwarf From K2Does the Measured Abundance Suggest a Biological Origin for the Ancient Alkanes Preserved in a Martian Mudstone?Carboniferous recumbirostran elucidates the origins of terrestrial herbivoryOcean Species Discoveries 28–30 — new species of chitons (Mollusca, Polyplacophora) and a public naming competitionRadar-based observation of a lava tube on VenusFormalization and inevitability of the Pareto principleLight to Heavy, Brief to Eternal: An Axion for Every Occasion (in the Early Universe)Reading TEA leaves for de novo protein designA toolkit for programmable transcriptional engineering across eukaryotic kingdomsTemporal dynamics of microbiome communities within urban compost piles undergoing the heat processIntroducing geoboundariesPaleontology R Packages to Benefit from Software Sustainability Institute GrantAdvancing Bioinformatics, Translational Bioinformatics and Computational Biology Research (R01 Clinical Trial Optional)ProteanR Packages:mixpower: Simulation-Based Power Analysis for Mixed-Effects Models aesopR: Tools for Text Analysis of Aesop's Fables ohvbd: One Health VBD Hub statuser: Statistical Tools Designed for End Users

Welcome to Science Research Weekly, Season 5, Episode 3, Cave Robots in Space. Get ready for endoplasmic reticulum remodeling, marine bacteria streamlining shortcomings, robotic run-throughs of space-cave explorations, non-exponential growth for AI, viral protein immune escape constraints, the Top 40 new CRAN packages of December 2025, and pilot projects from the NIH on using common fund data sets. Science On.References:ER remodelling is a feature of ageing and depends on ER-phagyCell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbationCooperative robotic exploration of a planetary skylight surface and lava caveProtein Autoregressive Modeling via Multiscale Structure GenerationPrimordial black holes as cosmic accelerators of light dark matter: Novel direct detection constraintsAre AI Capabilities Increasing Exponentially? A Competing HypothesisHabitat fragmentation controls bacterial community composition outcomesConstrained Evolutionary Funnels Shape Viral Immune EscapeA deep-learning-based score to evaluate multiple sequence alignmentsDecember 2025 Top 40 New CRAN Packagescaugi (Causal Inference), phylospatia (Genetics), distionary (Statistics), svgedit (Utilities)Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)R Packages:regextable: Pattern-Based Text Extraction and Standardization with Lookup Tablesfru: A Blazing Fast Implementation of Random Forestmarinepredator: Marine Predators Algorithm

Get ready for supermassive dark stars, human creativity versus AI, unsinkable metal tubes, robot-assisted microscopy, the Collaborative Microbial Metabolite Center knowledgebase, and a grant to strengthen agricultural systems. Science On.References:https://www.mdpi.com/2218-1997/12/1/1https://www.nature.com/articles/s41598-025-25157-3https://iopscience.iop.org/article/10.3847/PSJ/ae2b6f/pdfhttps://advanced-onlinelibrary-wiley-com.ezproxy.library.und.edu/doi/epdf/10.1002/adfm.202526033https://arxiv.org/pdf/2601.20849https://arxiv.org/pdf/2601.20808https://arxiv.org/pdf/2601.20776https://www.biorxiv.org/content/10.64898/2026.01.24.701521v1https://www.biorxiv.org/content/10.64898/2026.01.27.698081v1https://www.biorxiv.org/content/10.64898/2026.01.27.701945v1https://simpler.grants.gov/opportunity/c026db8a-157d-42de-bac7-4baf5602cd0aR Packages:glmSTARMA: (Double) Generalized Linear Models for Spatio-Temporal Datarepfun: Create Tables, Listings and Figures using Functions Styled after SAS™ MacrosGimmeMyStats: Statistics Utilities

Science Research Weekly is back, with new content, deeper dives, and all the science updates you’ve been craving. This week, from viruses in space to 3D visualizations of automotive undercarriages, we’re covering scientific articles, preprints, software, blogs, and grant opportunities. Science On.References:https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003568https://www.nature.com/articles/s41587-025-02962-9https://www.nature.com/articles/s41586-025-09971-3https://www.jstatsoft.org/issue/view/v115https://arxiv.org/pdf/2601.14213https://arxiv.org/pdf/2601.14208https://www.biorxiv.org/content/10.64898/2026.01.20.700692v1.full.pdfhttps://www.biorxiv.org/content/10.64898/2026.01.17.700094v1.full.pdfhttps://journal.r-project.org/issues/2025-3/https://www.r-bloggers.com/2026/01/setting-up-a-cluster-of-tiny-pcs-for-parallel-computing-a-note-to-myself/https://blogs.sas.com/content/iml/2026/01/07/9-dataviz-distrib-sas-part1.htmlhttps://blogs.sas.com/content/iml/2026/01/14/9-dataviz-distrib-sas-part_2.htmlhttps://www.vastspace.com/science-rfp-eligibilityR-PACKAGES:col2hex2col: Convert Between Color Names and Hex CodesVennItem: Generate Venn Diagrams with Items Listed in the Sections

Welcome to the final episode of Science Research weekly for 2025. Covering November and December.

Get ready for the PRIMA system to treat age-related blindness, surprising chemistry on Saturn's moon Titan, Kagome tubes for vibration damping in engineering, the R-Multiverse, and a grant on the Foundations of a Resilient Microbiome. Science On.References:Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMDSnOx Nanoflakes as Enhanced Near-Infrared Photothermal Therapy Agents Synthesized from Electrochemically Oxidized SnS2 PowdersHydrogen cyanide and hydrocarbons mix on TitanTopological polarization of kagome tubes and applications toward vibration isolationPotassium-40 isotopic evidence for an extant pre-giant-impact component of Earth’s mantleOverlay multiple custom density curves on a histogram in SASGo for Launch! Packages Shipped to the R-MultiverseWhat’s new for Python in 2025?leap: Foundations of a Resilient MicrobiomeChan Zuckerberg Initiative: Implementation of Synthetic Biology Principles in ImmunologyR Packages:alpmixBayes: Bayesian Estimation for Alpha-Mixture Survival ModelsbayesQRsurvey: Bayesian Quantile Regression Models for Complex Survey Data Analysisarete: Automated REtrieval from TExtnbpInference: Inference on Average Treatment Effects for Continuous Treatmentspartialling.out: Residuals from Partial Regressions

Get ready for neuronal nanotubes, comet versus alien for interstellar object 3I/ATLAS, rain on the Sun, the R Journal 17/2, citation metric distortion, and more new Science Spotlight videos. Science On.References:Intercellular communication in the brain through a dendritic nanotubular networkIs the Interstellar Object 3I/ATLAS Alien Technology?Spatiotemporal Low First Ionization Potential Abundance: A Catalyst for Coronal CondensationTree swallows as indicators of per- and polyfluoroalkyl substance exposure and effects at select Department of Defense sites along the East Coast and at sites with different sources in the Upper Midwest, United States90% of science is lost. This new AI just found itR Journal Volume 17/2New, work-in-progress book on spatial data visualization in RBeyond Fraud: How IHME Distorts Academic MetricsScience SpotlightR Packages:descsuppRplots: Generate Plots for All Variables in Descriptive Tablesmedicalcoder: Tools for Working with ICD Codes and Comorbidity AlgorithmsGINAX: Performs Genome-Wide Iterative Fine-Mapping for Non-Gaussian Data using GINA-XeasyRef: Easy Reference Generation for R Packages

Get ready for chromosomal instability suppression in breast cancer, the marine origins of leeches, metal-laced hydrogels, better simulations in R, and a grant on Precision Mitochondria. Science On.References:Epigenetic regulation of chromosomal instability by EZH2 methyltransferaseThe first leech body fossil predates estimated hirudinidan origins by 200 million yearsHydrogel-Based Vat Photopolymerization of Ceramics and Metals with Low Shrinkages via Repeated Infusion PrecipitationDeploy Multiple Shiny Apps from One R PackageA new simstudy function to make simulating replications easierARIA: Precision MitochondriaR Packages:mda.biber: Functions for Multi-Dimensional Analysispwranova: Power Analysis of Flexible ANOVA Designs and Related Testssummarytabl: Generate Summary Tables for Continuous, Ordinal, and Categorical Data

Get ready for direct pain relief, pollutant breakdown with biochar, shark-attack resistant wetsuits, an updated timetree for Fungi, edible electronics, simulating the Monty Hall problem in R, the Top 40 New CRAN Packages for August 2025, and the DARPA Young Faculty Award. This episode covers material from September 26th to October 2nd. Science On.References:Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammationThe geologic history of marine dissolved organic carbon from iron oxidesStructure-performance relationship of biochar for direct degradation of organic pollutantsDOLPHIN advances single-cell transcriptomics beyond gene level by leveraging exon and junction readsEffectiveness of bite-resistant materials to reduce injuries from white shark (Carcharodon carcharias) and tiger shark (Galeocerdo cuvier) bitesNanotechnology-driven coordination of shoot–root systems enhances rice nitrogen use efficiencyDetection of organic compounds in freshly ejected ice grains from Enceladus’s oceanA timetree of Fungi dated with fossils and horizontal gene transfersPrinted Integrated Logic Circuits Based on Chitosan-Gated Organic Transistors for Future Edible SystemsSimulating Monty Hall’s ProblemPlotting Distributions in RAugust 2025 Top 40 New CRAN PackagesSpurious Correlations in R – Correlation is not CausationLearning And Exploring The Workflow of RNA-Seq Analysis – A Note To MyselfDARPA: Young Faculty Award (YFA) 2026R Packages:eDNAfuns: Working with Metabarcoding Data in a Tidy Formatspuriouscorrelations: Datasets with Strong and Spurious Correlations

Get ready for a review of acetaminophen and neurodevelopmental disorders, dehydration and stress response, Hycean world woes, hints at the compositional protein code, fraudulent publishing in mathematics, R Journal Volume 17/1, and a grant on microbial dust control for mining operations. Science On.References:Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodologyHabitual fluid intake and hydration status influence cortisol reactivity to acute psychosocial stressSub-Neptunes Are Drier than They Seem: Rethinking the Origins of Water-rich WorldsA domed pachycephalosaur from the early Cretaceous of MongoliaTracing the Origin of the Genetic Code and Thermostability to Dipeptide Sequences in ProteomesTiny protein pairs may hold the secret to life’s originHow to Fight Fraudulent Publishing in the Mathematical Sciences: Joint Recommendations of the IMU and the ICIAMFraudulent Publishing in the Mathematical SciencesThe R Journal Volume 17/1Birthdays and the coupon collector's problemNIH: Pilot Projects to Enhance the Human Virome ProgramNIH: Clinical Trial Readiness for Rare Diseases, Disorders, and SyndromesNSF/CASIS Transport Phenomena Research at the International Space Station to Benefit Life on EarthMicrobial dust control and surface stabilizationR Packages:bnpMTP: Bayesian Nonparametric Sensitivity Analysis of Multiple Testing Procedures for p ValuesMicrobTiSDA: Microbiome Time-Series Data Analysisplumber2: Easy and Powerful Web ServersggDNAvis: 'ggplot2'-Based Tools for Visualising DNA Sequences and Modifications

Get ready for maize shoot stem cells, a five image Einstein cross, identity of some Little Red Dots, ATREIDES for exo-Neptunes, Volume 114 of the Journal of Statistical Software, ggplot2 geoms and stats, and Classic Scientific Paper Review. Science On.References:Journal of Statistical Software Volume 114Large-scale single-cell profiling of stem cells identifies redundant regulators of shoot development and yield trait variationHerS-3: An Exceptional Einstein Cross Reveals a Massive Dark Matter HaloA remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5Journal of Statistical Software Volume 114All the Ways to Programmatically Edit or Parse R Markdown / Quarto DocumentsLearning About Assemblying DNA, BLAST, and Multiple Loci Sequence Testing (MLST) – A Note To MyselfExploring {ggplot2}’s Geoms and StatsClassic Scientific Paper ReviewR Packages:henna: A Versatile Visualization Suiteccar3: Canonical Correlation Analysis via Reduced Rank RegressionSurvGME: Analysis of Survival Data under Graphical and Measurement Error Modelsworkspace: Manage Collections of Datasets and Objects

Get ready for Martian mudstone biosignatures, a wide-ranging dwarf planet candidate, mapping mammoth microbes, ice gliding diatoms, extrachromosomal Inocles of the oral microbiome, DNA sequence alignment from scratch in R, and an invitation to check out Science Spotlight. Science On.References:Redox-driven mineral and organic associations in Jezero Crater, MarsDiscovery of a dwarf planet candidate in an extremely wide orbit: 2017 OF201Ancient host-associated microbes obtained from mammoth remainsIce gliding diatoms establish record-low temperature limits for motility in a eukaryotic cellGiant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiomeCreating and managing Canvas quizzes with R/exams and vvcanvasBuilding DNA Sequence Alignment With Needleman-Wunsch Algorithm From Scratch - A Note To My SelfScience SpotlightR Packages:factorH: Multifactor Nonparametric Rank-Based ANOVA with Post Hoc Testsivolcano: Interactive Volcano PlotREXoplanets: Creates Interface with NASA 'Exoplanets Archive API'pmsesampling: Sample Size Determination for Accurate Predictive Linear Regressionminipdf: PDF Document Creatorpower4mome: Power Analysis for Moderation and Mediation

Get ready for the failure of beta-blockers, cathartocytosis, flagging suspicious journals with AS, extreme ankylosaur armor, the basics of phylogenetic analysis in R, and a tiny space grant from DevelopSpace. Science On.References:Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EMBeta-Blockers after Myocardial Infarction without Reduced Ejection FractionCathartocytosis: Jettisoning of cellular material during reprogramming of differentiated cellsEstimating the predictability of questionable open-access journalsExtreme armour in the world’s oldest ankylosaurPatterned invagination prevents mechanical instability during gastrulationLearning The Basics of Phylogenetic AnalysisDevelopSpace grantR Packages:blendR: Blended Survival CurvesCompClassMetrics: Classification Measures when Subclasses are InvolvedTrialSimulator: Clinical Trial SimulatorRnaught: Estimate the Basic Reproduction Number (R0)metamorphr: Tidy and Streamlined Metabolomics Data WorkflowstastyR: Recipe Data from 'Allrecipes.com'

Get ready for deep-ocean oxidation dates, no giant impact for Jupiter’s core, common meds making antibiotic resistance worse, arsenic-mineralizing marine worms, the July 2025 Top 40 new CRAN packages, a plea for PyPAN: the Python Package Archive Network, and a grant on aging mammalian tissues in vitro. Science On. References:Mid-Devonian ocean oxygenation enabled the expansion of animals into deeper-water habitatsNo dilute core produced in simulations of giant impacts on to JupiterThe effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coliA deep-sea hydrothermal vent worm detoxifies arsenic and sulfur by intracellular biomineralization of orpiment (As2S3)July 2025 Top 40 New CRAN PackagesHow many parameters does GPT-5 have?Python needs its CRANThe European Bioconductor ConferenceNIH: Aging Mammalian Tissues In VitroNIH: Stephen I. Katz Early Stage Investigator Research Project Grant (non-clinical trial)NIH: Stephen I. Katz Early Stage Investigator Research Project Grant (human subjects)R Packages:ham: Healthcare Analysis Methodsmultideploy: Deploy File Changes Across Multiple 'GitHub' RepositoriesSampleSizeCalculator: Sample Size Calculator under Complex Survey Designtidypopgen: Tidy Population Geneticsmlspatial: Machine Learning and Mapping for Spatial Epidemiologygwas2crispr: GWAS-to-CRISPR Data Pipeline for High-Throughput SNP Target Extractionggdiceplot: Dice Plot Visualization for 'ggplot2'

Get ready for a potential cancer vaccine, a carbon ring stabilized by smaller rings, Uranus’ newest tiny moon, absurd conversions in R, and funding from the American Lung Association. Science On.References:Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreadingSolution-phase stabilization of a cyclocarbon by catenane formationSwRI-led Webb Telescope survey discovers new moon orbiting UranusPython Developers Survey 2024 ResultsHandling Missing Data in R: A Comprehensive GuideLearning Antimicrobial Resistance (AMR) genes with BioconductorLittle useless-useful R functions – Absurd converter with Markdown reportAmerican Lung Association: Awards and Grants OpportunitiesR Packages:Nematode: Ecological Indices Calculator for Nematode CommunitiesconfidenceCurves: Frequentist Confidence Analysis for Clinical Trialsggdiagram: Object-Oriented Diagram Plots with 'ggplot2'csdb: An Abstracted System for Easily Working with Databases with Large Datasetsgtregression: Tools for Creating Publication-Ready Regression Tables

Get ready for Antarctic submarine canyons, a medicated gel for diabetic wound healing, rapid electronic detection of infectious and chronic diseases, SAS and R in tandem, and several grants from private foundations. Science On.References:The geomorphometry of Antarctic submarine canyonsEngineered sEVs encapsulated in GelMA facilitated diabetic wound healing by promoting angiogenesis via targeting thrombospondin-1 Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at the Subfemtomolar LevelBuilding seamless data pipelines across multiple languages: A life sciences and healthcare use case leveraging R and SASGateway for Cancer Research Grant ProgramIAFNS Cognitive Health Committee Request for ProposalsSimons Collaborations in Ecology and Evolution

Get ready for the power of iNaturalist in biodiversity research, mechanisms behind lightning strikes, multi-region brain organoids, programmable chromosome engineering, an idealized double-slit experiment, why hardware may need a new foundation, animated maps in R, and a grant from PepsiCo on novel proteins. Science On.References:iNaturalist accelerates biodiversity research Photoelectric Effect in Air Explains Lightning Initiation and Terrestrial Gamma Ray FlashesMulti-Region Brain Organoids Integrating Cerebral, Mid-Hindbrain, and Endothelial SystemsIterative recombinase technologies for efficient and precise genome engineering across kilobase to megabase scalesInhibition of the minor spliceosome restricts the growth of a broad spectrum of cancersCoherent and Incoherent Light Scattering by Single-Atom Wave PacketsEinstein was wrong: MIT just settled a 100-year quantum debateSurfactants Steer Supraparticle StructureJournal of Statistical Software Volume 113Why Hardware Needs a New Foundation3 ways to estimate parameters when fitting a distribution to dataIntroduction to Generalised Linear Models with Prussian Horse KicksAnimated Maps with {ggplot2} and {gganimate}Novel proteins, peptides and amino acids with health benefits

Get ready for radiation-hardened data chips, a universal Deepfake detector, plant virus cancer immunotherapy, June’s top 40 new CRAN packages, and a grant from the NSF on Future Computing Research. Science On.References:A Radiation-Hard 8-Channel 15-Bit 40-MSPS ADC for the ATLAS Liquid Argon Calorimeter ReadoutTowards a Universal Synthetic Video Detector: From Face or Background Manipulations to Fully AI-Generated ContentComparative analyses for plant virus-based cancer immunotherapy drug developmentJune 2025 Top 40 New CRAN PackagesNSF Computer and Information Science and Engineering (CISE): Future Computing ResearchR Packages:ggdibbler: Add Uncertainty to Data VisualisationssimIC: Simulate and Analyze Interval- and Mixed-Censored Survival DatasuRface.analytics: Statistical Analysis and Visualization of Surface-Engineered Material Propertiesstaninside: Facilitating the Use of 'Stan' Within Packagesggcorrheatmap: Make Flexible 'ggplot2' Correlation Heatmaps

Get ready for cancer cells going up in sugary flames, live-action planetary formation, deep sea plastic biodegradation, a 150-year-old museum fossil specimen finally gets figured out, The R Journal: Volume 16/4, dealing with non-values in R, and some Science Spotlights. Science On.References:A Novel Exopolysaccharide, Highly Prevalent in Marine Spongiibacter, Triggers Pyroptosis to Exhibit Potent Anticancer EffectsLiDO: Discovery of a 10:1 Resonator with a Novel Libration StateRefractory solid condensation detected in an embedded protoplanetary diskUnveiling deep-sea biodegradation of microbially produced lactate-based polyester (LAHB) via plastisphere metagenomics and metatranscriptomicsPalaeocampa anthrax, an armored freshwater lobopodian with chemical defenses from the CarboniferousThe R Journal: Volume 16/4Let’s talk about NA-s!What is Biological Dark Matter?What Makes Functional Precision Cancer Therapy Useful?R Packages:dependentsimr: Simulate Omics-Scale Data with DependencyROCnGO: Fast Analysis of ROC Curves

Get ready for Parkinson’s disease sniffing dogs; the bladed microtube scheme for massive magnetic fields; a giant, spinning black hole merger; ghost galaxies; lasagna plots in SAS; and an NSF grant on Programmable Cloud Laboratories. Science On.References:Trained dogs can detect the odor of Parkinson's diseaseGigagauss magnetic field generation by bladed microtube implosionDynamic Organization of Cells in Colonic Epithelium is Encoded by Five Biological RulesGW231123: a Binary Black Hole Merger with Total Mass 190-265 Encoding hierarchical 3D architecture through inverse design of programmable bonds100 ghost galaxies may be orbiting the Milky Way—and we’re just now uncovering themJournal of Statistical Software Volume 113Use a lasagna plot to visualize US gas pricesExploring R and Rust in Bioinformatics – Online Developer Forum, 28 July 2025How to choose an IDEStandard Deviation vs. Standard Error: Meaning, Misuse, and the Math Behind the ConfusionNSF Test Bed: Toward a Network of Programmable Cloud LaboratoriesNASA ROSES 2025: F.9 Citizen Science Seed Funding ProgramR Packages:rfriend: Provides Batch Functions and Visualisation for Basic Statistical ProceduresclusterWebApp: Universal Clustering Analysis PlatformfusedTree: Fused Partitioned Regression for Clinical and Omics Dataironseed: Improved Random Number Generator Seedingjunco: Create Common Tables and Listings Used in Clinical Trialsggtranslate: A 'ggplot2' Extension for Translating Plot Text

Get ready for Big Five Workouts, CryoRhodopsins, double detonation supernovae, moon-rice, the 4 layers of testing for R packages, and a three-track grant from the NSF on Translation to Practice. Science On.References:Personality traits can predict which exercise intensities we enjoy most, and the magnitude of stress reduction experienced following a training programCryoRhodopsins: A comprehensive characterization of a group of microbial rhodopsins from cold environmentsThe genome of a sea spider corroborates a shared Hox cluster motif in arthropods with a reduced posterior tagmaRegulating Multifunctional Oxygen Vacancies for Plasma-Driven Air-to-Ammonia ConversionCalcium in a supernova remnant as a fingerprint of a sub-Chandrasekhar-mass explosionRestoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s disease–linked LRRK2-mutant miceMoon-Rice: Developing the perfect crop for space-basesThe 4 Layers of Testing Every R Package NeedsElevate Your Skills and Boost Your Career with Jumping Rivers Free Monthly WebinarsNSF: National Science Foundation Translation to PracticeR Packages:BMIselect: Bayesian MI-LASSO for Variable Selection on Multiply-Imputed Datasetsgggda: A 'ggplot2' Extension for Geometric Data Analysisreptiledbr: Interface to the Reptile Database for Querying and Retrieving Taxonomic DatasemEffect: Structural Equation Model Effect Analysis and Visualization

Get ready for cancer cell states, ADHD diagnosis difficulties, body profiles from Ediacaran trace fossils, LMMS for work you can do yourself, May 2025 Top 40 New CRAN Packages, and a Google Research grant for Quantum Neuroscience. This episode covers materials from June 27th to July 3rd. Science On.References:AAnet resolves a continuum of spatially-localized cell states to unveil intratumoral heterogeneityDiagnosing ADHD in adults in randomized controlled studies: a scoping reviewQuantitative decoding of Ediacaran locomotory trace fossil morphologies: Evidence for the emergence of slender anterior-posterior body profiles Size-Insensitive Vapor Diffusion Enabled by Additive Freeze-Printed Aerogels for Scalable DesalinationYou can outsource the grunt work to an LLM, not expertiseMay 2025 Top 40 New CRAN PackagesBeyond the Basics: Books to Supercharge Your R SkillsDOD: Air Force Fiscal Year 2026 Young Investigator Program (YIP)NASA: Innovative Advanced Concepts (NIAC) Phase IGoogle Research: Quantum NeuroscienceR Packages:autograph: Automatic Plotting of Many GraphsgemR: General Effect Modelling

Get ready for UV-resistant lichen, microbes for bioprinting Martian regolith, a new mammalian organelle called the hemifusome, and ways to make candlestick and segmented total bar charts in R. Science On.References:UVC-Intense Exoplanets May Not Be Uninhabitable: Evidence from a Desert LichenBio-Manufacturing of Engineered Living Materials for Martian Construction: Design of the Synthetic CommunityLineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsaeHemifusomes and interacting proteolipid nanodroplets mediate multi-vesicular body formationAnatomy of a Normal Probability PlotHow to draw a candlestick chart in R? – Both ggplot2 and plotlySegmented Total Bar Chart in R with “`ggsegmentedtotalbar“`Fantastic Graph Types and How to Make ThemR Packages:clinpubr: Clinical Publicationslopes: Calculate Slopes of Roads, Rivers and Trajectoriesunsum: Reconstruct Raw Data from Summary Statistics

Get ready for Pandora’s box of respiratory pathogens, mixed-up earthworm genomes, the insane energies of Extreme Nuclear Transits, a virus-like clade of Archaea, R version 4.5.1 codename “Great Square Root", the new declarative physical modeling language Dyad, Post-Bayesianism using R, and the NIH Directors Transformative Research Awards. Science On.References:Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung MicrobiotaTowering behavior and collective dispersal in Caenorhabditis nematodesAn episodic burst of massive genomic rearrangements and the origin of non-marine annelidsThe most energetic transients: Tidal disruptions of high-mass starsEstimates of submicron particulate matter (PM1) concentrations for 1998–2022 across the contiguous USA: leveraging measurements of PM1 with nationwide PM2·5 component dataLandscape-explicit phylogeography illuminates the ecographic radiation of early archosauromorph reptilesA cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genomeR 4.5.1 is released2024 PSF Annual Impact ReportDyad: A New Language to Make Hardware Engineering as Fast as SoftwareBoost ML accuracy with hyperparameter tuning (with a fun twist)Creating A Question Bank Using Google Sheet, Plumber, and Digital Ocean DropletPost Bayesianism? Let's Try ItDoD: Breast Cancer, Breakthrough Award L1 & 2NIH: Support for Research Excellence First Independent Research (SuRE-First) Award NIH: Directors Transformative Research AwardsR Packages:geess: Modified Generalized Estimating Equations for Small-Sample Datagseries: Improve the Coherence of Your Time Series Datassutil: Sample Size Calculation Toolstidyspec: Spectroscopy Analysis Using the Tidy Data Philosophy

Get ready for pain killing at the nerve level, solving an Earth science seismic anomaly, ocean giant virus genomes, the SAS Hackathon, a warning against scientific vibe coding, and a pilot study testing school lunches. Science On.References:The analgesic paracetamol metabolite AM404 acts peripherally to directly inhibit sodium channelsThe texture of the post-perovskite phase controls the characteristics of the D” seismic discontinuityExpansion of the genomic and functional diversity of global ocean giant virusesSAS HackathonVibe coding with AI agents is not for scientistsRethinking Image FormatsHHS: A Research Study of Contaminants in School MealsR Packages:ggtime: Grammar of Graphics and Plot Helpers for Time Series Visualizationdiscovr: Interactive Tutorials and Data for "Discovering Statistics Using R and RStudio"rifttable: Results Tables to Bridge the Rift Between Epidemiologists and Their Data

Get ready for eDNA everything, Romer’s Gap tetrapods, dinosaur soft tissues for cancer research, the R Journal Volume 16/3, and a caution about correlation versus causation. Science On.References:Shotgun sequencing of airborne eDNA achieves rapid assessment of whole biomes, population genetics and genomic variationNano-structured antibiofilm coatings based on recombinant resilinNew U-Pb constraints and geochemistry of the East Kirkton Quarry, Scotland: Implications for early tetrapod evolution in the CarboniferousPreserving Fossilized Soft Tissues: Advancing Proteomics and Unveiling the Evolutionary History of Cancer in DinosaursA transiting giant planet in orbit around a 0.2-solar-mass host starR Journal 16/3Correlation vs Causation: Understanding the DifferenceR Packages:glmmsel: Generalised Linear Mixed Model Selection

Get ready for cardiovascular aging via gut bacteria metabolites, the darkening of the global ocean, horizontal gene transfer in eukaryotes, long-period radio transients now with X-rays, the R Journal Volume 16/2, and an Industry-University Cooperative Research Centers Program from the NSF. Science On.References:Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during agingDarkening of the Global OceanImpact plasma amplification of the ancient lunar dynamoHorizontal transmission of functionally diverse transposons is a major source of new intronsDetection of X-ray emission from a bright long-period radio transientThe R Journal Volume 16/2useR! 2025 Virtual ConferenceCustom PowerPoints Using {officer}April 2025 Top 40 New CRAN PackagesNSF: Industry-University Cooperative Research Centers ProgramSPARK NS Translational Research ProgramR Packages:RobinCID: Robust Inference in Complex Innovative Trial Designmissr: Classify Missing Data as MCAR, MAR, or MNAR

Get ready for spatial genome regulation in non-bilaterian animals, revamping antibiotics with endolysins, removing microplastics with okra and fenugreek, snake anti0venom from a hyperimmune legend, T. rex’s Asian heritage, the 30 Day Chart Challenge 2025, and a rare cancer grant from the Department of Defense. This episode covers material from May 2nd to May 8th. Science On.References:Chromatin loops are an ancestral hallmark of the animal regulatory genomeBacteriophage-derived endolysins restore antibiotic susceptibility in β-lactam- and macrolide-resistant Streptococcus pneumoniae infectionsFenugreek and Okra Polymers as Treatment Agents for the Removal of Microplastics from Water SourcesDesign of diverse, functional mitochondrial targeting sequences across eukaryotic organisms using variational autoencoderSnake venom protection by a cocktail of varespladib and broadly neutralizing human antibodiesRise of the king: Gondwanan origins and evolution of megaraptoran dinosaursGravity from transactions: fulfilling the entropic gravity programSimulating A Simple Response Adaptive Randomization – I Have To See It To Believe ItModel Diagnostics: Statistics vs Machine Learning30 Day Chart Challenge 2025DoD Rare Cancers, Concept AwardR Packages:automatedtests: Automating Choosing Statistical TeststidySummaries: Tidy Statistical Summaries for Exploratory Data AnalysisVIProDesign: A Comprehensive Tool for Protein Design

Get ready for the Eos dark molecular cloud, integrating exposomics into biomedicine, Cas9 for metabarcoding, time capsules in JuliaHub, the Top 40 New CRAN Packages for March 2025, and a grand on Exponentiating Mathematics. Science On.References:A nearby dark molecular cloud in the Local Bubble revealed via H2 fluorescenceIntegrating exposomics into biomedicineCas9-based enrichment for targeted long-read metabarcodingReproduce Scientific Research with JuliaHub’s Time CapsuleThe SMOTE method for generating synthetic dataMarch 2025 Top 40 New CRAN Packagesflags: Fun with FlagsExplained vs. Predictive Power: R², Adjusted R², and BeyondAnnouncing… schematicDOD: Exponentiating Mathematics (expMath)International Space Science Institute Visting ScientistsR Packages:robcat: Robust Categorical Data AnalysisbirdnetR: Deep Learning for Automated (Bird) Sound Identificationconnector: Streamlining Data Access in Clinical ResearchIssueTrackeR: List Things to Do

Get ready for DNA mutation rates across the generations, a potential Alzheimer’s ‘vaccine’, tissue-expansion mass-spectrometry, updating old methods in SAS, planning a statistical analysis, and seven new Cancer Grand Challenges. Science On.References:Human de novo mutation rates from a four-generation pedigree referenceTargeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaquesTEMI: tissue-expansion mass-spectrometry imagingUpdating old SAS programs: A case study with PROC LOESSStrategies for Choosing and Planning a Statistical AnalysisUSAMRAA: Alzheimer’s Research Program Transforming Research AwardCancer Grand ChallengesR Packages:circlizePlus: Using 'ggplot2' Feature to Write Readable R Code for Circular Visualizationglmfitmiss: Fitting GLMs with Missing Data in Both Responses and Covariates

Get ready for a rotating universe, universal cephalopod PCR primers, moonglass solar panels, R’s How about a Twenty-Six, SAS for Dummies 3rd Edition, and a grant for life science entrepreneurs. Science On.References:Can rotation solve the Hubble Puzzle?Development of universal PCR primers for the environmental DNA metabarcoding of cephalopod (Mollusca) diversityAcoustic modulation of mechanosensitive genes and adipocyte differentiationMoon photovoltaics utilizing lunar regolith and halide perovskitesJournal of Statistical Software Vol 112SAS For Dummies: New edition for the modern SAS userR version 4.5.0R Version 4.5.0 is Out!What’s new in R 4.5.0?Announcing the Jumping Rivers Dashboard GalleryGetting My Feet Wet With `Plumber` and JavaScriptNSF: Incorporating Human Behavior in Epidemiological ModelsBioInnovation Institute: Bio Studio ProgramR Packages:fastqrs: Fast Algorithms for Quantile Regression with Selectionvayr: Extensions for 'ggplot2' to Visualize as You Randomizee2tree: Explainable Ensemble Trees

Get ready for majestic herds of prehistoric rhinos, open-source 3D-printed robot parts, a mitochondrial disease therapy, a global map of human subcellular architecture, potential but scanty microbial life on Titan, and oxygen adaptation in bacteria. Science On.References:Enamel carbon, oxygen, and strontium isotopes reveal limited mobility in an extinct rhinoceros at Ashfall Fossil Beds, Nebraska, USADevelopment of an Open-Source 3D-Printed Material Synthesis Robot FLUID: Hardware and Software Blueprints for Accessible Automation in Materials ScienceFLUID (Flowing Liquid Utilizing Interactive Device) in operationSmall molecules restore mutant mitochondrial DNA polymerase activityMultimodal cell maps as a foundation for structural and functional genomicsThe Viability of Glycine Fermentation in Titan's Subsurface OceanA geological timescale for bacterial evolution and oxygen adaptationOverview of Clinical & Translational ResearchR Packages:correlationr: Conduct Robust Correlations on Non-Normal DataseinfitR: Modeling the Relationship Between Nematode Densities and Plant GrowthDLMRMV: Distributed Linear Regression Models with Response Missing Variableslme4GS: 'lme4' for Genomic Selection

Get ready for Green Saharan genomes, super-duckweed, Alzheimer’s blood tests, Volume 112 of the Journal of Statistical Software, a Litmus test for R packages, and the Top 40 New CRAN Packages for February 2025. Science On.References:Ancient DNA from the Green Sahara reveals ancestral North African lineageDuckweed genomes and epigenomes underlie triploid hybridization and clonal reproductionPlasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s diseaseGenome duplication in a long-term multicellularity evolution experimentCooperative hydrodynamics accompany multicellular-like colonial organization in the unicellular ciliate StentorJournal of Statistical Software, Volume 112Did George Box say, "All models are wrong, but some are useful"?Nested bar charts in SASBayesian proportional hazards model for a stepped-wedge designShould I Use Your R Package?February 2025 Top 40 New CRAN PackagesR Packages:castgen: Estimate Sample Size for Population Genomic StudiesClassificationEnsembles: Automatically Builds 20 Classification ModelsForecastingEnsembles: Time Series Forecasting Using 23 Individual ModelsNumericEnsembles: Automatically Runs 23 Individual and 17 Ensembles of Modelspcpr: Principal Component Pursuit for Environmental Epidemiology

Get ready for nuclear batteries, DIY box filters, Asgardian microtubules, water from the cosmic dawn, FitQuantiles tables in SAS, Teaching Combinatorics Using R, The 2025 Galaxy and Bioconductor Community Conference, and Python in 10 Lunch Break sessions. Science On.References:A safe nuclear battery that could last a lifetimeDo-it-yourself box filter clears the air of indoor pollutantsLong-chain alkanes preserved in a Martian mudstoneMicrotubules in Asgard archaeaDiverse ssRNA viruses associated with Karenia brevis harmful algal blooms in southwest FloridaAutonomous shaping of the piRNA sequence repertoire by competition between adjacent ping-pong amplification sitesAbundant water from primordial supernovae at cosmic dawnThe quantile fit plot: Comparing empirical and predicted quantiles for a univariate modelA Bayesian proportional hazards model for a cluster randomized trialHow Many Ways to Color This Grid: Teaching Combinatorics Using RGalaxy and Bioconductor Community Conference 2025Python in 10 Lunch Break Session 1R Packages:COAP: High-Dimensional Covariate-Augmented Overdispersed Poisson Factor Modelgghourglass: Plot Records per Time of DayGoMiner: Automate the Mapping Between a List of Genes and Gene Ontology Categories

Get ready for cell cycle synced endosymbionts, cytoskeleton densities via deep learning, taking the STING out of autoimmune diseases, constraints on the internal matter of neutron stars, and a protein association grant from the American Heart Association. Science On.References:A nucleus-encoded dynamin-like protein controls endosymbiont division in the trypanosomatid Angomonas deaneiDeep learning-based cytoskeleton segmentation for accurate high-throughput measurement of cytoskeleton densityArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammationQCD Constraints on Isospin-Dense Matter and the Nuclear Equation of StateAHA: Pilot Grants to Explore the Use of the American Heart Association Protein Binding Atlas to Discover Novel Protein InteractionsR Packages:globpso: Swarm Intelligence OptimizationminimalistGODB: Build a Minimalist Gene Ontology (GO) Database (GODB)kitesquare: Visualize Contingency Tables Using Kite-Square PlotsSnowData: Historical Data from John Snow's 1854 Cholera Outbreak Map

Get ready for the cancer and non-cancer cells of the colocatome, tiny vortexes in semimetals, slimmed down megasharks, Pi to the power of pi, and underrated R functions. Science On.References:A quantitative spatial cell-cell colocalizations framework enabling comparisons between in vitro assembloids and pathological specimensImaging Orbital Vortex Lines in Three-Dimensional Momentum SpaceReassessment of the possible size, form, weight, cruising speed, and growth parameters of the extinct megatooth shark, Otodus megalodon (Lamniformes: Otodontidae), and new evolutionary insights into its gigantism, life history strategies, ecology, and extinctionJulia Now Available on Google ColabPi to the power of piUnderrated Gems in R: Must-Know Functions You’re Probably Missing Out On9 new books added to Big Book of RCustomize your expedition: Create a unique documentation for your R PackageR Packages:datapackage: Creating and Reading Data Packageslavaan.mi: Fit Structural Equation Models to Multiply Imputed DataParamANOVA: Fully Parameterizable ANOVA Testsxlr: Create Table Summaries and Export Neat Tables to 'Excel'

Get ready for synthetic microbe community therapy, VR taste testing, narwhal tusk behavior, detecting space debris, microbial patterns across the ISS, the Top 40 New CRAN Packages for January 2025, and Department of Defense grants for the MURI program. Science On.References:A designed synthetic microbiota provides insight to community function in Clostridioides difficile resistanceA sensor-actuator–coupled gustatory interface chemically connecting virtual and real environments for remote tastingUse of tusks by narwhals, Monodon monoceros, in foraging, exploratory, and play behaviorThe generation of whistler, lower hybrid, and magnetosonic waves by satellites passing through ionospheric magnetic field aligned irregularitiesThe International Space Station has a unique and extreme microbial and chemical environment driven by use patternsR version 4.4.3 (Trophy Case) has been releasedA Bayesian proportional hazards model with a penalized splineConstructing the Hertzsprung-Russell DiagramWorking with Clinical Trial Data? There’s a Pharmaverse Package for ThatJanuary 2025 Top 40 New CRAN PackagesBetter documentation for R-universe!DoD: Multidisciplinary Research Program of the University Research Initiative (MURI)R Packages:MetabolSSMF: Simplex-Structured Matrix Factorisation for Metabolomics Analysismixtree: A Statistical Framework for Comparing Sets of TreesmbX: A Comprehensive Microbiome Data Processing Pipelineblit: Bioinformatics Library for Integrated Tools

Get ready for PAN-GO, tardigrade medication, the unsung biological driving forces of fire and ice, brewing tea for lead reduction, and the 2025 NASA ROSES omnibus. Science On.References:A compendium of human gene functions derived from evolutionary modellingLocal structural flexibility drives oligomorphism in computationally designed protein assembliesRadioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigradesThe Neoproterozoic glacial broomAnomalous δ15N values in the Neoarchean associated with an abundant supply of hydrothermal ammoniumBrewing Clean Water: The Metal-Remediating Benefits of Tea PreparationUse the EFFECTPLOT statement to visualize binomial regression models in SASNASA ROSES 2025: A.58 INNOVATER Packages:mermboost: Gradient Boosting for Generalized Additive Mixed Modelsqountstat: Statistical Analysis of Count Data and Quantal Datacodelist: Working with Code Lists

Get ready for exoplanet atmosphere, secret shark bases, 3D-printed thrusters, active matter, dependent variables that can’t be used for linear models, and bible translations in R. Science On.References:Vertical structure of an exoplanet’s atmospheric jet streamShallow seamounts are “oases” and activity hubs for pelagic predators in a large-scale marine reserveHigh-Impulse, Modular, 3D-Printed CubeSat ElectrosprayThrusters Throttleable via Pressure and Voltage ControlAberrant neuronal hyperactivation causes an age-dependent behavioral decline in Caenorhabditis elegansAn aperiodic chiral tiling by topological molecular self-assemblyTraveling Strings of Active Dipolar Colloids6 Types of Dependent Variables that will Never Meet the Linear Model Normality AssumptionWhat’s Artificial Intelligence all about?Generalized Linear Mixed Models for EverythingThe Last Statistical Model You’ll Ever Need in SAS Coupon: 92F7BB1DF31947F16207R Packages:logos: Access to the Hebrew, Greek, and English Version of the BiblemusicXML: Data Sonification using 'musicXML'indexr: A Thoughtful Saver of Results