Bye bye gadolinium! PRIME demonstrates bpMRI as good as mpMRI

An episode of the GU Cast | Urology Podcast podcast, hosted by Professor Declan Murphy & Dr Renu Eapen, titled "Bye bye gadolinium! PRIME demonstrates bpMRI as good as mpMRI" was published on September 10, 2025 and runs 28 minutes.

September 10, 2025 ·28m · GU Cast | Urology Podcast

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Summary

Episode Description

Big news today with the publication in JAMA of the eagerly anticipated PRIME study, a prospective multicentre trial comparing biparametric (bp) with multiparametric (mp) MRI in men suspected of having prostate cancer. Of course, mpMRI includes contrast enhanced sequences following injection of gadolinium, adding time, cost, plus the burden of gadolinium to bpMRI, and there have been suggestions that bpMRI may be just as effective as mpMRI for detecting clinically significant prostate cancer.
We are joined today by trial PI Veeru Kasivisvanathan (Urologist, UCL, London), and Francesco Giganti (Radiologist, UCL, London), to discuss the findings and what this means going forward. And it is all good news!

Your host Declan Murphy is on his own today while Renu Eapen on the road in Singapore.

Even better on our YouTube channel

Links below:
JAMA paper published today
Twitter: @compassurology @veerukasi @giga_fra
Website: compassurology.org

Funders:
John Black Charitable Foundation, Prostate Cancer UK, European Association of Urology Research Foundation, Wolfgang.Dieckmann Foundation.