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🧠 Can the aging brain still make new neurons? episode artwork

EPISODE · Feb 27, 2026 · 4 MIN

🧠 Can the aging brain still make new neurons?

from Dr RR Baliga's "Got Knowledge Doc" Podkast · host MasterMedFacts LLC

Can the aging brain still make new neurons?   A landmark 2026 Nature study analyzed 355,997 human hippocampal nuclei using single-nucleus RNA sequencing and ATAC sequencing. Neurogenesis persists into adulthood—but chromatin accessibility collapses early in Alzheimer's disease.   SuperAgers showed a 2.5-fold increase in immature neurons and a preserved resilience signature.   Epigenetics may be the earliest battlefield in cognitive decline. 🧠

Episode metadata supplied by the publisher feed · Published Feb 27, 2026

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🧠 Can the aging brain still make new neurons?

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This episode was published on February 27, 2026.

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