Can We Prevent Schizophrenia and Dementia? What the Science Suggests | Ep. 280 episode artwork

EPISODE · Aug 12, 2025 · 55 MIN

Can We Prevent Schizophrenia and Dementia? What the Science Suggests | Ep. 280

from The Aging Well Podcast · host Jeff Armstrong

What if schizophrenia and dementia weren’t inevitable? What if we could intervene—before symptoms ever appear?In this episode of 'The Aging Well Podcast', we welcome Dr. Leonard Lado—psychiatrist, researcher, and author of a bold new unified model of schizophrenia. Drawing from decades of personal and professional experience, Dr. Lado outlines how our understanding of brain development, inflammation, and connectivity is converging into a model that could radically change how we prevent and treat severe mental illness.We also discuss the promise of Transcranial Magnetic Stimulation (TMS) as a non-invasive, neuroplasticity-boosting tool for early intervention—offering new hope for those at risk of both psychosis and cognitive decline.If you or someone you love has been affected by schizophrenia, dementia, or chronic stress-related brain changes, this is an episode that offers both science and hope.Topics include:• The six models of schizophrenia—and how they connect• Why dopamine isn’t the full story• Inflammation and immune dysfunction in brain development• The role of TMS in rewiring and restoring the brain• What early intervention might look like for mental illness and dementia• Why neuroplasticity is more complex (and promising) than we thoughtDr. Leonard Lado is the Medical Director of the Lado Healing Institute and a leading voice in integrative psychiatry.Learn more at https://ladohealingpeople.com/Please, support The Aging Well Podcast by hitting the ‘like’ button, subscribing/following the podcast, sharing with a friend, and….BUY the products you need to… age well from our trusted affiliates and support the mission of The Aging Well Podcast*.The Aging Well Podcast merchandise | Show how you are aging well | Use the promo code AGING WELL for free shipping on orders over $75 | https://theagingwellpodcast-shop.fourthwall.com/promo/AGINGWELLRebalance Health | products created by hormone health experts to lower cortisol, improve sleep, and minimize the impact of stress on the body and mind | Use promo code AGINGWELL for 20% discount at https://rebalancehealth.comProlon | The Fasting Mimicking Diet (FMD) is a revolutionary five-day nutrition program scientifically formulated to mimic the effects of a prolonged water fast while still allowing nourishment - supporting the benefits of fasting without the challenges and risks that come from water-only fasts. | For the best available discount always use this link: https://prolonlife.com/theagingwellpodcastThrive25—Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffreyL-Nutra Health | The medical division of L-Nutra, focused onhelping people manage and potentially reverse chronic health conditions, like type 2 diabetes, prediabetes, insulin resistance, and obesity, using personalized, lifestyle-based programs grounded in evidence, not prescriptions. | Use this link: https://l-nutrahealth.com/theagingwellpodcastFusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | 15% off Code: AGINGWELL | https://fusionaryformulas.com/Jigsaw Health | Trusted supplements. “It’s fun to feel good.” | Click the following link for 10% off: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Auro Wellness | Glutaryl—Antioxidant spray that delivers high doses of glutathione (“Master Antioxidant”) | 10% off Code: AGINGWELL at https://aurowellness.com/?ref=1957Dr Lewis Nutrition | Fight neurodegeneration and cognitive decline with Daily Brain Care by Dr Lewis Nutrition—a proven daily formula designed to protect and restore brain function. | 10% off code: AGINGWELL or use the link: https://drlewisnutrition.com/AGING WELLTruDiagnostic—Your source for epigenetic testing | 12% off Code: AGEWELL or use the link: https://shop.trudiagnostic.com/discount/AGEWELL*We receive commission on these purchases. Thank you.

What if schizophrenia and dementia weren’t inevitable? What if we could intervene—before symptoms ever appear?In this episode of 'The Aging Well Podcast', we welcome Dr. Leonard Lado—psychiatrist, researcher, and author of a bold new unified model of schizophrenia. Drawing from decades of personal and professional experience, Dr. Lado outlines how our understanding of brain development, inflammation, and connectivity is converging into a model that could radically change how we prevent and treat severe mental illness.We also discuss the promise of Transcranial Magnetic Stimulation (TMS) as a non-invasive, neuroplasticity-boosting tool for early intervention—offering new hope for those at risk of both psychosis and cognitive decline.If you or someone you love has been affected by schizophrenia, dementia, or chronic stress-related brain changes, this is an episode that offers both science and hope.Topics include:• The six models of schizophrenia—and how they connect• Why dopamine isn’t the full story• Inflammation and immune dysfunction in brain development• The role of TMS in rewiring and restoring the brain• What early intervention might look like for mental illness and dementia• Why neuroplasticity is more complex (and promising) than we thoughtDr. Leonard Lado is the Medical Director of the Lado Healing Institute and a leading voice in integrative psychiatry.Learn more at https://ladohealingpeople.com/Please, support The Aging Well Podcast by hitting the ‘like’ button, subscribing/following the podcast, sharing with a friend, and….BUY the products you need to… age well from our trusted affiliates and support the mission of The Aging Well Podcast*.The Aging Well Podcast merchandise | Show how you are aging well | Use the promo code AGING WELL for free shipping on orders over $75 | https://theagingwellpodcast-shop.fourthwall.com/promo/AGINGWELLRebalance Health | products created by hormone health experts to lower cortisol, improve sleep, and minimize the impact of stress on the body and mind | Use promo code AGINGWELL for 20% discount at https://rebalancehealth.comProlon | The Fasting Mimicking Diet (FMD) is a revolutionary five-day nutrition program scientifically formulated to mimic the effects of a prolonged water fast while still allowing nourishment - supporting the benefits of fasting without the challenges and risks that come from water-only fasts. | For the best available discount always use this link: https://prolonlife.com/theagingwellpodcastThrive25—Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffreyL-Nutra Health | The medical division of L-Nutra, focused onhelping people manage and potentially reverse chronic health conditions, like type 2 diabetes, prediabetes, insulin resistance, and obesity, using personalized, lifestyle-based programs grounded in evidence, not prescriptions. | Use this link: https://l-nutrahealth.com/theagingwellpodcastFusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | 15% off Code: AGINGWELL | https://fusionaryformulas.com/Jigsaw Health | Trusted supplements. “It’s fun to feel good.” | Click the following link for 10% off: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Auro Wellness | Glutaryl—Antioxidant spray that delivers high doses of glutathione (“Master Antioxidant”) | 10% off Code: AGINGWELL at https://aurowellness.com/?ref=1957Dr Lewis Nutrition | Fight neurodegeneration and cognitive decline with Daily Brain Care by Dr Lewis Nutrition—a proven daily formula designed to protect and restore brain function. | 10% off code: AGINGWELL or use the link: https://drlewisnutrition.com/AGING WELLTruDiagnostic—Your source for epigenetic testing | 12% off Code: AGEWELL or use the link: https://shop.trudiagnostic.com/discount/AGEWELL*We receive commission on these purchases. Thank you.

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Can We Prevent Schizophrenia and Dementia? What the Science Suggests | Ep. 280

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This episode was published on August 12, 2025.

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What if schizophrenia and dementia weren’t inevitable? What if we could intervene—before symptoms ever appear?In this episode of 'The Aging Well Podcast', we welcome Dr. Leonard Lado—psychiatrist, researcher, and author of a bold new unified model...

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