Central Dogma for the MCAT: Transcription, Translation & ...

What this episode covers

DNA doesn’t “do", it instructs. In this episode of the Jack Westin MCAT Podcast, Mike and Molly walk through the central dogma, how we go from DNA → RNA → protein—and the regulation that makes different cells, well, different. Perfect for MCAT Bio/Biochem: we hit transcription, RNA processing, translation mechanics (A–P–E sites), start/stop codons, eukaryote vs. prokaryote differences, and multi-layered gene expression regulation (chromatin, transcription factors, miRNA/siRNA, ubiquitin, & more).🔑 What you’ll learnCentral dogma overview (DNA → RNA → protein)Transcription: promoter, template vs. coding strand, initiation/elongation/terminationEukaryotic RNA processing: 5′ cap, splicing (introns vs. exons, alternative splicing), poly-A tailTranslation: AUG start (Met), codons/anticodons, tRNA charging, ribosome A–P–E sites, stop codons (UAA/UAG/UGA)Eukaryotes vs. Prokaryotes: 40/60/80S vs. 30/50/70S ribosomes, coupled transcription–translation, operons (lac/trp)Regulation: heterochromatin vs. euchromatin, histone acetylation, DNA methylation, transcription factors, miRNA/siRNA silencing, post-translational mods (ubiquitin, phosphorylation)Want to learn more? Shoot us a text at 415-855-4435 or email us at [email protected]! 📱📌 Free Academic Advising: https://calendly.com/academic-advising-4/jack-westin-academic-advising?utm_source=spotify&utm_medium=podcast💻 Try our Chrome Extension (video solutions to every AAMC passage) https://tinyurl.com/4jw5pad8📚 Free Resources: https://jackwestin.com?utm_source=spotify&utm_medium=podcast🎓 Live Education Sessions: https://jackwestin.com/sessions?utm_source=youtube&utm_medium=podcast👨🏻‍🏫 Courses: https://jackwestin.com/courses?utm_source=spotify&utm_medium=podcast🙋 Tutoring: https://jackwestin.com/services/live-online-mcat-tutoring?utm_source=spotify&utm_medium=podcast📸 Follow Us On Instagram: https://www.instagram.com/jackwestinmcat?utm_source=spotify&utm_medium=podcast👥 Join our Facebook Study Group: https://www.facebook.com/groups/freemcatprep?utm_source=spotify&utm_medium=podcast

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Frequently Asked Questions

How long is this episode of Jack Westin MCAT Podcast?

This episode is 1 hour and 4 minutes long.

When was this Jack Westin MCAT Podcast episode published?

This episode was published on October 15, 2025.

What is this episode about?

DNA doesn’t “do", it instructs. In this episode of the Jack Westin MCAT Podcast, Mike and Molly walk through the central dogma, how we go from DNA → RNA → protein—and the regulation that makes different cells, well, different. Perfect for MCAT...

Can I download this Jack Westin MCAT Podcast episode?

Yes, you can download this episode by clicking the download button on the episode player, or subscribe to the podcast in your preferred podcast app for automatic downloads.