Diazepam

Trade: Valium Class: Benzodiazepine MOA: Binds to the benzodiazepine receptor and enhances the effects of GABA Indications: Anxiety, Skeletal muscle relaxation, anticonvulsant Contraindications: Children younger then 6 months, acute angle glaucoma, CNS depression, alcohol intoxication. Side effects: Respiratory depression, drowsiness, fatigue, headache, pain at the injection site, confusion, nausea, hypotension, cardiac arrest at high doses •Dosing: Adult: Anxiety: 2-10mg IV/IM Seizure: 5-10mg IV/IO Pediatric: Anxiety: 0.2 – 0.3mg/kg IV/IM Seizure: Older then 5 years: 1mg IV/IO Older then 30 days less then 5 years: 0.2 to 0.5mg IV/IO Neonate: 0.1-0.3mg/kg IV/IO