Dr. Jessica Shepherd, MD – Menopause, Hormone Therapy and Bone Health episode artwork

EPISODE · Jan 29, 2026 · 49 MIN

Dr. Jessica Shepherd, MD – Menopause, Hormone Therapy and Bone Health

from Longevity Optimization with Kayla Barnes-Lentz · host Kayla Barnes-Lentz

In this episode, Dr. Jessica Shepard, board-certified OB/GYN and Chief Medical Officer of Hers, shares that the FDA just removed the black box warning on hormone replacement therapy after 23 years. We discuss what actually happened with the WHI study that created all the fear around estrogen and breast cancer, and why the research never actually supported that narrative.Dr. Shepard explains why you shouldn't wait until menopause to start the HRT conversation and how starting in your perimenopausal years can make all the difference for long-term health. Dr. Shepard shares the essential labs she runs on patients including ApoB, HbA1c, and thyroid optimization, plus the longevity metrics women should be tracking.We also get into supplement recommendations including why she recommends 10 grams of creatine daily, the role of inflammation in aging, and how estrogen is naturally anti-inflammatory which is why women see increased cardiovascular risk and metabolic dysfunction after menopause.Kayla's social + website:Instagram:  kaylabarnesTikTok:  femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comSpotify: https://open.spotify.com/show/4OLWWn2...Apple: https://podcasts.apple.com/us/podcast...Follow Her Female Protocol: https://www.protocol.kaylabarnes.comDr. Jessica Shepherd's social + website:Website: https://www.jessicashepherdmd.com/Instagram: https://www.instagram.com/jessicashepherdmd/Transform Your Health: https://eudemonia.net/?utm_source=podcast&utm_medium=kayla-podcast&utm_campaign=jessica-shepherd

Episode metadata supplied by the publisher feed · Published Jan 29, 2026

Embed this episode

NOW PLAYING

Dr. Jessica Shepherd, MD – Menopause, Hormone Therapy and Bone Health

0:00 49:13

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

No similar episodes found.

No similar podcasts found.

Frequently Asked Questions

How long is this episode of Longevity Optimization with Kayla Barnes-Lentz?

This episode is 49 minutes long.

When was this Longevity Optimization with Kayla Barnes-Lentz episode published?

This episode was published on January 29, 2026.

Can I download this Longevity Optimization with Kayla Barnes-Lentz episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.
URL copied to clipboard!