Dr. Zach Bush: How the Microbiome Affects Metabolism, Brain Health, and Chronic Disease episode artwork

EPISODE · Aug 13, 2026 · 1H 14M

Dr. Zach Bush: How the Microbiome Affects Metabolism, Brain Health, and Chronic Disease

from hol+ with Dr. Taz MD | The Future of Medicine is Holistic · host Dr. Taz MD

Join The Circle and use code "PODCAST": https://holplus.co/circle/ What if chronic disease, declining energy, cognitive issues, and fertility challenges are not isolated problems, but signs of a deeper disconnection from the natural world?In this episode of hol+ with Dr. Taz MD, Dr. Zach Bush explores the relationship between human health and the health of our environment. Drawing from his background in internal medicine, endocrinology, cancer research, and hospice care, he explains how his search for the root causes of disease led him from the hospital and laboratory to the microbiome, soil science, and regenerative agriculture.Dr. Bush describes mitochondria as essential generators of cellular energy and explains how the microbes living within and around us help support metabolism, immunity, neurological function, and communication throughout the body. He shares his perspective on how chemical agriculture, declining biodiversity, and changes in our food systems may be affecting these biological relationships.Dr. Taz and Dr. Bush also discuss the rise of obesity, insulin resistance, autoimmune disease, cognitive decline, chronic fatigue, and infertility. Dr. Bush presents his theory that these conditions may be connected through a broader decline in metabolic energy and our increasing separation from nature.The conversation ultimately turns toward hope and practical action. Dr. Bush explains why restoring soil, supporting regenerative farmers, growing food, strengthening local communities, and spending more time in direct contact with nature may help rebuild both human and planetary health. He also shares how something as simple as growing a mint plant can begin restoring a family’s relationship with living food.In this episode:Dr. Bush’s journey from conventional medicine to microbiome and soil researchWhat mitochondria do and why they are essential for cellular energyHow the microbiome influences metabolism, immunity, and brain functionThe relationship between soil health, food quality, and human healthHow chemical agriculture may disrupt biological communicationWhy Dr. Bush describes modern illness as nature deficit disorderHis theory connecting metabolic decline with chronic disease and fertilityWhy supplements cannot fully replace a healthy food systemHow regenerative agriculture can support human and planetary healthSimple ways to reconnect your family with food, soil, and natureWhy community and human connection may be essential parts of healingAbout Dr. Zach Bush:Dr. Zach Bush is a triple board-certified physician specializing in internal medicine, endocrinology and metabolism, and hospice and palliative care. His work has focused on the relationships between the microbiome, human health, environmental health, food systems, and regenerative agriculture. After years of working in conventional medicine and biomedical research, Dr. Bush began exploring how soil health, biodiversity, and chemical exposure may influence human metabolism and chronic disease. His work helped give rise to Project Biome and Farmer’s Footprint, initiatives focused on regenerative food systems and restoring the relationship between human and planetary health.Connect with Dr. Zach Bush:https://zachbushmd.com/https://www.instagram.com/zachbushmd/https://farmersfootprint.us/About Dr. Taz:Dr. Tasneem Bhatia (Dr. Taz) is a triple board-certified integrative medicine physician, bestselling author, and founder of hol+, a multi-location integrative medicine practice.Learn more: https://doctortaz.com/aboutStay Connected:Connect further with hol+ at https://holplus.co/ and don’t forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Book a Hol+ Consultation:https://holplus.co/locations/virtual/Follow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast:https://holplus.transistor.fm/subscribeSubscribe to the video podcast:https://www.youtube.com/@DrTazMD/podcastsProduced by https://ClipGrowth.com (Producer: Pat Gostek)

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