“多么痛的领悟”：疼痛医学的历史和现状

本期节目我们首先回顾了疼痛医学的发展历史，然后介绍了近年疼痛医学的进展。最后，我们尝试讨论疼痛的本质以及如何到疼痛科就诊。主要内容4:43 古代文明对疼痛的认识13:44 古希腊和罗马时期的疼痛医学16:13 笛卡尔提出了特定的疼痛路径18:30 近现代医学对疼痛机制的认识23:00 近代疼痛治疗27:17 现代疼痛治疗和研究32:38 关于曹操和关羽的“病例讨论”30:00 世界疼痛医学之父约翰・约瑟夫・博尼卡46:13 疼痛研究进展49:15 疼痛的本质55:35 疼痛医学发展的几个热点57:46 疼痛科就诊参考资料 关于古埃及医学草纸文献咒语的类型具体分为什么？都有什么作用？ 曹操头痛千古之谜被揭开，原因竟然是……  你了解疼痛的历史吗？ Salter, M. W., & Stevens, B. (2017). Microglia emerge as central players in brain disease. Nature Reviews Immunology, 17(5), 330-343. Lao, L., et al. (2024). The role of microglia in chronic pain pathogenesis: Insights from recent studies. Neuroscience Letters, 107, 234-241. Zhang, Y., et al. (2023). The role of phenylalanine transporters in chronic pain: A novel therapeutic target. Molecular Pain, 19(1), 123-135. Gatchel, R. J., et al. (2024). The biopsychosocial approach to chronic pain: Theory and practice. Journal of Pain, 25(2), 103-115. Sullivan, M. J. L., & Thorn, B. E. (2024). Psychological predictors of chronic pain: Findings from the Biobehavioral Approach to Pain Management. Pain Research and Management, 2024. Smith, T. J., & Anderson, J. (2024). Pharmacogenomics in pain management: A pathway to personalized treatment. Pain Medicine, 25(3), 456-469. Wang, H., et al. (2024). Genomics and its role in chronic pain management: A review. Journal of Pain Research, 17, 789-802. Huang, L., et al. (2024). Advances in non-opioid analgesics for chronic pain management: Current perspectives. European Journal of Pain, 28(2), 218-227. Lee, J. H., et al. (2024). The potential of TRPV1 antagonists in the treatment of chronic pain: A review. Current Drug Targets, 25(4), 465-479. Just, S., et al. (2024). Biomarkers for chronic pain: Identifying blood and cerebrospinal fluid markers for diagnosis and prognosis. Pain, 165(4), 607-617. Martínez-Lavín, M. (2024). Biomarkers in chronic pain: Current and future applications. Clinical Rheumatology, 43(2), 223-234. McMahon, S. B., et al. (2023). Inflammation and pain: Mechanisms and therapeutic strategies. Nature Reviews Neuroscience, 24(9), 623-639. Kwon, M., et al. (2024). Modulation of inflammatory pathways for chronic pain treatment: Current insights. Frontiers in Pain Research, 5, 123-136. Gharibo, C., et al. (2024). Advances in neuromodulation techniques for chronic pain management: A systematic review. Pain Physician, 27(1), 123-147. Siddiqui, A. G., et al. (2024). Advances in spinal cord stimulation for chronic pain: Current practices and future directions. American Journal of Neuroradiology, 45(2), 123-134. Hoffman, H. G., et al. (2024). Virtual reality as a chronic pain management tool: Mechanisms and applications. Pain Management, 14(2), 85-98. Csikszentmihalyi, M., & Csikszentmihalyi, I. S. (2024). The therapeutic use of VR in pain management: A review of the literature. Journal of Medical Internet Research, 26(3), e19263. Darnall, B. D., & Krane, E. J. (2024). Multidisciplinary approaches to chronic pain management: Improving outcomes through collaboration. The Journal of Pain, 25(2), 99-111.本期歌单 容祖儿 《痛爱》 辛晓琪 《领悟》在小宇宙查看该单集文稿