E. 173 How To Use GLP-1s Without Losing Muscle or Regaining Weight | Dr. Christle Guevarra episode artwork

EPISODE · Jul 10, 2026 · 1H 4M

E. 173 How To Use GLP-1s Without Losing Muscle or Regaining Weight | Dr. Christle Guevarra

from Self-Selecting · host Cory Hageman

GLP-1 medications have completely changed the conversation around fat loss—but are they actually the right tool for you?In this episode, I sit down with family and sports medicine physician Dr. Christle Guevarra to explore the science, misconceptions, and real-world application of GLP-1 medications like Ozempic, Wegovy, and tirzepatide.We discuss how these medications influence hunger, food noise, reward pathways, and long-term behavior change, while also addressing common concerns surrounding muscle loss, dosing, training performance, libido, gray market peptides, and what happens after coming off the medication.Whether you're considering GLP-1s yourself, coaching clients who use them, or simply want an evidence-based understanding of these medications, this conversation provides the nuance that's often missing online.Timestamps:- [00:00 – 05:04] – Dr. Christle Guevarra's Background & Why GLP-1 Medications Changed Weight Loss- [05:04 – 10:09] – How GLP-1s Reduce Food Noise & Reward-Driven Eating- [10:09 – 19:12] – Scarcity Mindset, Food Behaviors & Who Benefits Most- [19:12 – 23:17] – Finding The Right GLP-1 Dose Without Sacrificing Nutrition- [23:17 – 26:27] – Why Aggressive Fat Loss & Oversized Deficits Backfire- [26:27 – 31:08] – Muscle Building, Staying Lean & Using GLP-1s Beyond Fat Loss- [31:08 – 32:40] – Building Sustainable Habits Before Coming Off Medication- [32:40 – 37:20] – What Happens After GLP-1s? Maintaining Results Long-Term- [37:20 – 41:59] – Setting Realistic Expectations & Understanding Your Fat Loss Goals- [41:59 – 51:21] – When GLP-1s May Cause More Harm Than Good- [51:21 – 54:49] – Women's Libido, Dieting & GLP-1 Side Effects- [54:49 – 1:00:50] – Gray Market GLP-1s, Retatrutide & Emerging Research- [1:00:50 – 1:04:59] – GLP-1s, Substance Use Disorders & Final TakeawaysLinks & Resources:Follow Dr. Christle Guevarra: https://www.instagram.com/dr.christle/?hl=enAccess The FREE GLP-1 Guide: https://drchristle.com/Purchase The Complete Fat Loss Guide: https://coryfit.com/product/the-complete-fat-loss-guide/Purchase The Glute Building Blueprint: https://coryfit.com/product/the-complete-glute-building-program/https://coryfit.com/⁠Coaching: Let's Chat⁠https://calendly.com/coryfit-coaching/15min⁠Consults: Book a Call⁠https://calendly.com/coryfit-coaching/one-time-consultationFor more content, follow along:⁠Instagram⁠: https://www.instagram.com/cory_fit/⁠Patreon⁠: https://patreon.com/CoryFit?utm_medium=unknown&utm_source=join_link&utm_campaign=creatorshare_creator&utm_content=copyLink

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E. 173 How To Use GLP-1s Without Losing Muscle or Regaining Weight | Dr. Christle Guevarra

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