E293: Tolerance and the Disappearing Buzz episode artwork

EPISODE · Aug 29, 2025 · 18 MIN

E293: Tolerance and the Disappearing Buzz

from Sober Powered: The Neuroscience of Being Sober · host Gillian Tietz, MS, CPRC

Have you ever thought back to the early days of your drinking and remembered how just one or two drinks gave you exactly what you wanted? That light, carefree buzz—the feeling that you were relaxed, loosened up, and maybe even a little funnier. Fast forward a few years, and suddenly those same two drinks barely register. You start chasing it—three, four, maybe more—and before you know it, the sweet spot is gone. Instead of a gentle buzz, you either feel nothing… or you’re over the line into drunk. That disappearing buzz is tolerance. And tolerance is the brain’s way of adapting to repeated exposure to alcohol. In this episode, I want to unpack exactly why the same amount of alcohol feels weaker over time, how tolerance develops in your brain, why it fuels heavier drinking, and why that easy, carefree buzz eventually disappears altogether. What to listen to next: E279: The Pendulum Effect of Healing E234: The Scary Side of How Alcohol Affects the Body E220: The Hippocampus and Alcohol: Blackouts, Memory Deficits, and Learned Associations Work with me: Community & Meetings: Living a Sober Powered Life https://www.soberpowered.com/membership Sober coaching https://www.soberpowered.com/sober-coaching  Weekly email: You’ll hear from me on Fridays https://www.soberpowered.com/email Free resources https://www.soberpowered.com/free Courses: The non-negotiable mindset https://www.soberpowered.com/mindset-course Don’t try harder, try different  https://www.soberpowered.com/willpower Support the show: If you enjoyed this episode please consider buying me a coffee to support all the research and effort that goes into this podcast https://www.buymeacoffee.com/soberpowered Thank you for supporting this show by supporting my sponsors https://www.soberpowered.com/sponsors Sources are posted on my website Disclaimer: all of the information described in this podcast is my interpretation of the research combined with my opinion. This is not medical advice.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Have you ever thought back to the early days of your drinking and remembered how just one or two drinks gave you exactly what you wanted? That light, carefree buzz—the feeling that you were relaxed, loosened up, and maybe even a little funnier. Fast forward a few years, and suddenly those same two drinks barely register. You start chasing it—three, four, maybe more—and before you know it, the sweet spot is gone. Instead of a gentle buzz, you either feel nothing… or you’re over the line into drunk. That disappearing buzz is tolerance. And tolerance is the brain’s way of adapting to repeated exposure to alcohol. In this episode, I want to unpack exactly why the same amount of alcohol feels weaker over time, how tolerance develops in your brain, why it fuels heavier drinking, and why that easy, carefree buzz eventually disappears altogether. What to listen to next: E279: The Pendulum Effect of Healing E234: The Scary Side of How Alcohol Affects the Body E220: The Hippocampus and Alcohol: Blackouts, Memory Deficits, and Learned Associations Work with me: Community & Meetings: Living a Sober Powered Life https://www.soberpowered.com/membership Sober coaching https://www.soberpowered.com/sober-coaching  Weekly email: You’ll hear from me on Fridays https://www.soberpowered.com/email Free resources https://www.soberpowered.com/free Courses: The non-negotiable mindset https://www.soberpowered.com/mindset-course Don’t try harder, try different  https://www.soberpowered.com/willpower Support the show: If you enjoyed this episode please consider buying me a coffee to support all the research and effort that goes into this podcast https://www.buymeacoffee.com/soberpowered Thank you for supporting this show by supporting my sponsors https://www.soberpowered.com/sponsors Sources are posted on my website Disclaimer: all of the information described in this podcast is my interpretation of the research combined with my opinion. This is not medical advice.  Learn more about your ad choices. Visit megaphone.fm/adchoices

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E293: Tolerance and the Disappearing Buzz

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This episode was published on August 29, 2025.

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Have you ever thought back to the early days of your drinking and remembered how just one or two drinks gave you exactly what you wanted? That light, carefree buzz—the feeling that you were relaxed, loosened up, and maybe even a little funnier. Fast...

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