ENaC ⚙️ RAAS ⚡ Immunity 🧬: The Gender Divide in Hypertension

🧂 Salt sensitivity of blood pressure (SSBP) is an independent risk factor for CVD.   🚹🚺 Women are more salt-sensitive than men, especially after menopause. ⚙️ Key drivers: RAAS, ENaC, natriuresis, and immune pathways. 💉 Estrogen protects, testosterone raises pressure, menopause tips the balance.   🐀 From Dahl's rats to Conn's syndrome, SSBP research shows why sex-specific, personalized therapy is the future of hypertension care.   🔗 Nature Reviews Cardiology