Ep. 54 Managing Sarcomas: A Multidisciplinary Approach with Dr. Yvette Ho and Dr. Jessica Jones

In this episode of The Back Table MSK Podcast, Dr. Alexa Levey discusses the importance of multidisciplinary treatment planning for sarcomas with Dr. Yvette Ho and Dr. Jessica Jones. --- CHECK OUT OUR SPONSOR Stryker Interventional Spine https://www.strykerivs.com --- SYNPOSIS The conversation explores the necessity of a multidisciplinary approach and the challenges associated with managing both osseous and soft tissue sarcomas. Dr. Jones highlights recent advancements in precision medicine, including a novel drug, nirogacesta, for desmoid tumors. Dr. Ho addresses common misconceptions surrounding desmoid tumors, emphasizing their potential for significant tissue destruction, and shares insights from her experience in limb salvage surgery. Dr. Levey discusses the considerations involved in needle biopsy and presents case studies where cryoablation effectively reduced desmoid tumor sizes. The doctors also discuss strategies for managing nociceptive and mechanical pain, such as intrathecal pain pumps, radiation therapy, and kyphoplasty. --- TIMESTAMPS 00:00 - Introduction 03:51 - Challenges in Sarcoma Management 13:06 - Precision Medicine in Treatment Planning 16:44 - The Role of Biopsy 20:51 - The Importance of Specialized Oncology Care 25:13 - Collaboration Throughout Treatment Course 31:03 - Cryoablation and Case Studies 35:13 - New Drug Development for Desmoid Tumors 39:06 - Limb Salvage Considerations 41:13 - Metastasis, Recurrence, and Pain Management 49:57 - Final Thoughts --- RESOURCES OGSIVEO (Nirogacestat): https://www.ogsiveo.com/