EPISODE · Jan 1, 2026 · 1H
Episode 129. Dr. Lara Briden, Beyond Willpower: Understanding Metabolism Through Biology, Not Blame
from One Thing with Dr. Adam Rinde · host Dr. Adam Rinde
Dr. Lara Briden challenges everything you think you know about metabolism, revealing why energy—not weight—is the true marker of metabolic health. This conversation explores how modern life has pushed our physiology into states it was never designed for, and offers a compassionate, science-based approach to understanding your body as a logical system rather than a problem to fix.GUEST INFORMATION:Name: Dr. Lara BridenTitle/Credentials: Naturopathic doctor, author, former evolutionary biology researcher Background: Has peer-reviewed publications and thesis in evolutionary biology, specializes in women's health with focus on centering female physiology as normal mammalian function EPISODE HIGHLIGHTS:Evolutionary Biology FrameworkDr. Briden explains how her background in evolutionary biology informs her medical practice, viewing women's bodies as logical systems that make biological sense Menopause as Evolutionary AdvantageDiscussion of how menopause evolved as a survival advantage, with post-reproductive women being essential for family group survival Debunking the Willpower MythChallenges the narrative that metabolic issues are about eating too much and exercising too little The Asthma AnalogyExplains why telling people to "just lose weight" is like telling someone with asthma to "just breathe better" Environmental FactorsDetails how environmental toxins, gut microbiome changes, and epigenetics contribute to metabolic dysfunction across species and generations Energy as Metabolic MarkerExplains metabolic flexibility and how the body should preferentially burn fat in fasting states Blood Sugar CrashesDiscusses how insulin resistance often presents as reactive hypoglycemia rather than high blood sugar Seed Oils DiscussionDr. Briden shares her perspective on high-dose omega-6 oils as metabolically problematic signaling molecules Nervous System and MetabolismExplores how the autonomic nervous system significantly impacts insulin sensitivity and metabolic rate Key Metabolic NutrientsDiscuss essential nutrients for metabolic health: magnesium, taurine, choline, inositol, and glycine, historically obtained from organ meats Mitochondria as MastersFascinating discussion of mitochondria as dynamic cellular powerhouses affected by emotions and social activity Lab Testing SimplifiedProvides practical lab markers for insulin resistance: ALT levels, ALT to AST ratio, and triglycerides RESOURCES MENTIONED:Metabolism Repair For Women, by Dr. BridenPeriod Repair Manual (previous book) Potential upcoming cookbook collaboration KEY TAKEAWAYS:Metabolism problems often come before weight gain, not after—it's about insulin resistance first Energy levels and satiety between meals are better indicators of metabolic health than body weight Environmental factors including toxins, processed oils, and gut dysfunction are major contributors to metabolic issues The body has a complex system that can't be micromanaged—focus on removing obstacles and supporting overall health Simple lab tests (ALT, triglycerides) can reveal insulin resistance more effectively than complex testing Website: https://www.larabriden.com/CALL TO ACTION:Subscribe to the One Thing Podcast for more conversations that challenge conventional health wisdom and center biology over blame. Share this episode with someone who's been struggling with metabolic health issues—these insights could be exactly what they need to hear.
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Episode 129. Dr. Lara Briden, Beyond Willpower: Understanding Metabolism Through Biology, Not Blame
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