Episode 149: A Biomarker to Predict MS Progression with Dr. Robert Fox and Caroline Sincock

The International Progressive MS Alliance is about to publish a paper that recommends advancing research on a specific biomarker to predict MS progression, and we're getting a pre-publication preview of what that paper is all about.   My guests are Dr. Robert Fox, a neurologist and Vice-Chair for Research at the Cleveland Clinic Neurological Institute, and Caroline Sincock, who lives with progressive MS. Both Doctor Fox and Caroline are members of the International Progressive MS Alliance Scientific Steering Committee and are among the authors of the new paper that we're going to preview.      We're also talking about the results of a study that show how increasing the energy in cells damaged by demyelination may stop MS progression.   We'll tell you why Mayzent failed to gain approval to treat active secondary progressive MS in England. We'll introduce you to the winner of the first Novartis Innovation Prize for Assistive Tech for Multiple Sclerosis. And we'll discuss study results that show that a protein in the blood called neurofilament light chain may predict MS progression.   We have a lot to talk about! Are you ready for RealTalk MS??! The 2020 ACTRIMS-ECTRIMS Virtual Conference  3:10 Boosting cellular energy at sites of myelin loss may stop MS progression  4:18 Why NICE failed to approve Mayzent to treat active secondary progressive MS    6:29 Novartis Innovation Prize awarded to AccessNow  9:04 Elevated neurofilament light chain may predict risk of MS progression  10:02 My Interview with Dr. Robert Fox and Caroline Sincock  11:27 Share this episode  42:11 Please Support the National MS Society COVID-19 Response Fund  42:30 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email:  https://realtalkms.com/149 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: [email protected]: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com National MS Society's Ask An MS Expert Video Replay What You Need to Know About Coronavirus (COVID-19) National MS Society COVID-19 Response Fund International Progressive MS Alliance STUDY: Enhanced Axonal Response of Mitochondria to Demyelination Offers Neuroprotection: Implications for Multiple Sclerosis AccessNow STUDY: Plasma Neurofilament Light Levels are Associated with Risk of Disability in Multiple Sclerosis Join the RealTalk MS Facebook Group Download the RealTalk MS App for iOS Download the RealTalk MS App for Android Give RealTalk MS a Rating and Review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 149 Hosted By: Jon Strum Guests: Dr. Robert Fox and Caroline Sincock Tags: MS, MultipleSclerosis, MSResearch, MSSociety, RealTalkMS Privacy Policy