Episode 328: Cognitive Rehabilitation and MS with Dr. Nancy Chiaravalloti

Cognitive dysfunction is a common symptom of multiple sclerosis, affecting more than half of the people living with MS. While cognitive issues like changes in memory, difficulty maintaining attention, slower information processing speed and executive function may not be among the most disabling symptoms of MS, they may be among the most disconcerting symptoms. Whether it's your short-term memory, the ability to find your way to a familiar destination that you've gone to hundreds of times, or your ability to follow conversations with friends or business colleagues, these are the kinds of real-world situations that can bring someone to a hard stop, recognizing that they're changing in profound ways that aren't outwardly apparent. And that's a scary feeling. Fortunately, researchers are making real progress in developing ways for people living with MS to improve their cognition. This week, Dr. Nancy Chiaravalloti joins me to talk about what researchers are learning and what types of cognitive rehabilitation are available today.  Dr. Chiaravalloti is the Director of the Center for Neuropsychology and Neuroscience Research and the Center for Traumatic Brain Injury Research at Kessler Foundation. Dr. Chiaravalloti's research is focused on ways to stimulate new learning, memory, and processing speed. We're also sharing some promising results from a preclinical study of an investigational Epstein-Barr Virus vaccine (And we'll explain why this is so important to the MS community!). Dr. Nuriel Moghavem will take us through a day in the life of an MS Fellow. We'll share the disappointing results of the Phase 3 clinical trial for Evobrutinib. And we'll tell you about super-small biological robots that seem capable of doing some amazing things -- including encouraging the growth of healthy nerve cells to replace damaged nerve cells. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Cognitive Rehabilition  :22 Promising news from a preclinical study of an investigational EBV vaccine  2:08 A day in the life of an MS Fellow with Dr. Nuriel Moghavem  4:21 Evobrutinib Phase 3 clinical trial has failed to meet its end points  17:19 Biological robots assemble into a "superbot" and encourage the growth of healthy nerve cells  18:28 Dr. Nancy Chiaravalloti discusses breakthrough treatment for cognitive dysfunction in MS  21:19 Share this episode  31:48 Have you downloaded the free RealTalk MS app?  32:08 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/328 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: [email protected] Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com STUDY: Motile Living Biobots Self-Construct from Adult Human Somatic Progenitor Seed Cells https://onlinelibrary.wiley.com/doi/10.1002/advs.202303575 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 328 Guests: Dr. Nuriel Moghavem and Dr. Nancy Chiaravalloti Privacy Policy