Episodio – Abatacept y tolerancia periférica: inhibición de la coestimulación T | USMLE Step 1

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BIENVENIDOS A UN NUEVO EPISODIO DE USMLE DREAMERSEn este episodio analizamos el mecanismo de acción de abatacept (CTLA4-Ig) en artritis reumatoide refractaria. Revisamos la señal doble necesaria para la activación del linfocito T, cómo la inhibición de CD28–CD80/86 induce anergia, y por qué esto se traduce en disminución de IL-2 e inflamación sistémica.#USMLEStep1 #Inmunologia #Farmacologia #Abatacept #CTLA4 #PeripheralTolerance #USMLEdreamers

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