Episodio – Hiperaldosteronismo primario: Conn, renina baja e hipokalemia | USMLE Step 1

from USMLE DREAMERS · host USMLE DREAMERS

En este episodio analizamos un caso clásico de hipertensión severa en un adulto joven con renina plasmática muy baja y episodios de debilidad muscular, un patrón que orienta a hiperaldosteronismo primario (síndrome de Conn). Revisamos la zona glomerulosa como fuente de aldosterona, la fisiología del túbulo colector (reabsorción de Na+ y secreción de K+ y H+), y por qué el exceso de aldosterona produce hipertensión con hipokalemia y alcalosis metabólica. Además, aclaramos el concepto de “aldosterone escape”: por qué, a pesar de retener sodio, la mayoría de pacientes no desarrolla edema periférico significativo. Cerramos con el enfoque diagnóstico (relación aldosterona/renina y pruebas de supresión) y el tratamiento según la causa (MRA vs resección quirúrgica).#USMLEDreamers #USMLE #Step1 #Medicina #Endocrinologia #Aldosterona #ConnSyndrome #Hipertension #Hipokalemia #Renina #RAAS #FisiologiaRenal

Episode metadata supplied by the publisher feed · Published Jan 8, 2026

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Episodio – Hiperaldosteronismo primario: Conn, renina baja e hipokalemia | USMLE Step 1

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