Episodio – Nicotínico vs muscarínico: receptores ionotrópicos y flujo inmediato de iones | USMLE Step 1

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En este episodio resolvemos una confusión clásica: diferenciar receptores ionotrópicos (canales iónicos) de receptores metabotrópicos (acoplados a proteína G). Partimos de un caso experimental donde un fármaco provoca un cambio inmediato en el flujo transmembrana de Na+, Ca2+ y K+ por apertura directa del canal. Con esa sola frase, identificamos al receptor nicotínico colinérgico y lo contrastamos con los receptores muscarínicos (M1/M3 vía IP3 y M2 vía cAMP). Te explico paso a paso la fisiología de la unión neuromuscular, el requisito de dos sitios de unión de ACh, y cómo convertir este tema en una regla mental imposible de olvidar.#USMLEDreamers #USMLE #Step1 #Farmacologia #Fisiologia #Neuro #Receptores #Nicotinico #Muscarinico #Ionotropico #Metabotropico #Acetilcolina

Episode metadata supplied by the publisher feed · Published Jan 7, 2026

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Episodio – Nicotínico vs muscarínico: receptores ionotrópicos y flujo inmediato de iones | USMLE Step 1

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