Episodio – RT-PCR y detección del gen de fusión BCR-ABL en LMC | USMLE Step 1

from USMLE DREAMERS · host USMLE DREAMERS

Paciente adulto con esplenomegalia masiva, anemia y leucocitosis. En este episodio revisamos cómo la translocación t(9;22) genera el gen de fusión BCR-ABL, por qué el producto es una tirosina cinasa constitutivamente activa y cómo la RT-PCR detecta el mRNA de fusión BCR-ABL en la LMC.#USMLE #Step1 #Hematología #CML #LMC #BCRABL #PCR #RTPCR #Oncogenes #TirosinaCinasa #USMLEDreamers

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This episode was published on November 27, 2025.

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