How GLP-1 Medications Work: Treating Obesity as a Disease

In this in-depth episode of Hormones & Hope, Dr. Chhaya Makhija is joined by obesity medicine specialist Dr. Sarah Stombaugh for a thoughtful, evidence-based conversation on obesity as a chronic disease and the evolving role of GLP-1 receptor agonists in long-term weight and metabolic health.Together, they unpack why obesity is not simply about willpower, how genetics, hormones, inflammation, and environment intersect, and where medications like GLP-1s fit into a comprehensive treatment plan. The discussion goes far beyond prescriptions—covering lifestyle integration, realistic expectations, ethical concerns around compounded medications, and why repairing our relationship with food may be the most important intervention of all.This episode is a must-listen for patients, clinicians, and anyone seeking clarity amid the noise surrounding modern weight-loss treatments.Dr. Sarah Stombaugh is a family medicine physician and diplomate of the American Board of Obesity Medicine. Graduating from Creighton University Medical School and completing her family medicine residency at University of Chicago, Dr. Stombaugh practiced outpatient primary care in Evanston, Illinois before moving to Charlottesville, Virginia with her family.Upon moving to Charlottesville, Dr. Stombaugh opened a private practice weight loss clinic, in which she sees patients in-person at her downtown Charlottesville office and by telemedicine throughout the states of Virginia and Illinois.In addition to her clinical work, Dr. Stombaugh is the host of the "Conquer Your Weight" podcast. Through this platform, she shares valuable insights, expert opinions, and practical advice on weight management, contributing to the well-being of a broader audience. Dr. Stombaugh believes in empowering both individuals and the medical community in order to promote an evidence-based approach to the treatment of obesity.Follow Dr. Chhaya Makhija here:https://www.instagram.com/chhayamakhijamd/https://www.facebook.com/unifiedendocrinehttps://unifiedendocrinecare.com/https://www.youtube.com/@chhayamakhijamdhttps://www.linkedin.com/in/chhayamakhijamd/Download the Free Guide 'Your Health on GLP-1' Here:https://dr-chhaya.myflodesk.com/glp1Follow Dr. Sarah Stombaugh here:https://www.sarahstombaughmd.com/https://www.sarahstombaughmd.com/glp/https://www.instagram.com/sarahstombaughmd/https://www.youtube.com/@SarahStombaughMDDisclaimer: This podcast is for educational, informational, and entertainment purposes only. It’s not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance.If you enjoyed this episode, don’t forget to subscribe to the Hormones & Hope Podcast for more expert insights, real conversations, and science-backed strategies to help you feel your best—inside and out.