How to Build a Baseline and Understand Your Risk

What this episode covers

For APOE4 carriers, knowing your risk is only useful if you know what to do with it. In this episode, Sarah walks through her path to developing a baseline, and discusses the labs that actually matter, fasting insulin, homocysteine, hs-CRP, Vitamin D etc. Sarah also discusses why standard functional medicine isn't specific enough for APOE4 biology, and how to interpret baseline data without losing your mind in the process.Whats in this episode: What APOE4 actually is, and what it isn'tWhy the "nothing you can do" frame is the most expensive mistake APOE4 carriers can makeThe research caveat problem: why so many studies don't apply to people like meHow I built my first baseline with blood work and cognitive testing before changing anythingWhy I started with Parsley Health and then moved to Dale Bredesen's PreCODE programWhat my PreCODE report revealed across metabolic, inflammatory, and cognitive domainsWhy my cognitive scores required more context than just a number on a page (ADHD, breastfeeding, medication status)Three practical takeaways for anyone at the beginning of this journeyWhy exercise leads Season 1, even though it wasn't where I startedShow Notes & References

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How long is this episode of Race Against Mind: An Alzheimer's Prevention Investigation?

This episode is 15 minutes long.

When was this Race Against Mind: An Alzheimer's Prevention Investigation episode published?

This episode was published on April 25, 2026.

What is this episode about?

For APOE4 carriers, knowing your risk is only useful if you know what to do with it. In this episode, Sarah walks through her path to developing a baseline, and discusses the labs that actually matter, fasting insulin, homocysteine, hs-CRP, Vitamin...

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Yes, a full transcript is available for this episode. You can read the complete transcript on the episode page.

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