Immunopeptidomics Offer New Hope in Cancer Research

In this episode of omgOMX, enter the world of immunopeptidomics with University of Oxford’s Associate Prof. Nicola Ternette. Nicola shares her humble beginnings in virology to becoming a leading expert in the field of immunology. Discover how mass spectrometry opened new doors for protein analysis and vaccine development how Nicola's lab is revolutionizing cancer therapy by profiling immune molecules in different diseases, and how this information can be used to direct clinical applicationsDon't miss this inspiring episode that showcases the power of women in science and the potential of immunopeptidomics to shape the future of cancer therapies. Hit that subscribe button and share this episode with fellow science enthusiasts!00:21 - Nicola's humble beginnings in virology, shaping her path to where she is today05:48 - Moving to the UK and her exposure to mass spectrometry at Benedict Kessler's proteomics facility07:43 - Working on HIV vaccines with experts to understand how infected cells appear to the immune system09:02 - Specializing in profiling immune molecules in diseases and cancer to inform vaccine development10:00 - The breakthrough realization of applying immune system knowledge to cancer research10:18 - Focusing on mechanistic research and profiling specific antigens for potential clinical applications11:29 - Collaboration with industry for cancer therapies and the importance of automation in research13:09 - Automating the process for analyzing broader sample cohorts and optimizing sample acquisition14:42 - The challenge of high-throughput analysis and the future of immunopeptidomics16:38 - The significance of validation in mass spectrometry workflows and antigen identification21:15 - The impact of the pandemic on vaccine research and its role in cancer therapy23:53 - Optimism about future advancements in immunopeptidomics and cancer immunotherapy27:56 - Surprising discoveries and expanding collaborations in industry and clinical partnerships30:32 - Balancing personal and professional life as an academic researcher Hosted on Acast. See acast.com/privacy for more information.