Impact of Metabolic Syndrome on Clinical Profile and Prognosis in Patients with Acute ST-Elevation Myocardial Infarction: a Cross-Sectional Study

Impact of Metabolic Syndrome on Clinical Profile and Prognosis in Patients with Acute ST-Elevation MyocardialInfarction: a Cross-Sectional Studyhttps://link.springer.com/article/10.1007/s42399-025-01822-6AbstractMetabolic syndrome (MS) has gained attention as a newly discovered risk factor for coronary artery disease (CAD).Studies have demonstrated that individuals with MS have a higher risk for coronary artery disease (CAD), and the risk is higher in females compared to males. Patients with metabolic syndrome have a higher incidence of ST-elevationmyocardial infarction (STEMI), making it a significant risk factor that has to be well-treated for successful secondary prevention. The study’s objective is to determine the frequency of MS in patients with acute STEMI according to the new “obesity-centric” IDF definition and to compare the clinical outcomes of acute STEMI patients with and without MS. A total of 132 consecutive patients with acute STEMI were analyzed, and 100 patients were included. MS wasidentified using criteria based on the “International Diabetes Federation 2005.” The frequency of metabolic syndrome in patients with STEMI was 46%. The frequency was greater in females (53.2%) than in males (43.2%). Patients whohad MS had poor clinical outcomes when compared to patients without MS, including mortality. Mortality due to STEMI in patients with MS was 15.2%, whereas in patients without MS was just 2% (p < 0.05). In addition to being a significant risk factor for cardiovascular disease, metabolic syndrome can also be a strong predictor of the severity and immediate prognosis of the condition.Disclaimer:Lupin makes no representation or warranty of any kind, expressed or implied, regarding the accuracy, adequacy, validity, reliability, availability, or completeness of any scientific information shared by the HCP on the ­­­STARUPDATE podcast. You should not allow the contents of this to substitute for your own medical judgment, which you should exercise in evaluating the information on this website.