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Inflammation 🔥, Dopamine 💊, and Apathy 😐: A Neuroimmune Pathway in Brain Fog? episode artwork

EPISODE · Apr 18, 2025 · 3 MIN

Inflammation 🔥, Dopamine 💊, and Apathy 😐: A Neuroimmune Pathway in Brain Fog?

from Dr RR Baliga's "Got Knowledge Doc" Podkast · host MasterMedFacts

Cancer cachexia isn't just weight loss—it's a hijacking of motivation 😔. Elevated IL-6 🔥 activates a brainstem-to-basal ganglia circuit 🧠 that suppresses dopamine 💊 in the nucleus accumbens, leading to effort-based apathy 💤. Blocking IL-6 or boosting dopamine restores drive without changing weight, revealing a treatable neuroimmune pathway 💡.

Episode metadata supplied by the publisher feed · Published Apr 18, 2025

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Inflammation 🔥, Dopamine 💊, and Apathy 😐: A Neuroimmune Pathway in Brain Fog?

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This episode was published on April 18, 2025.

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