Intuition: When Should We Trust It?

We often hear that we should "trust our instincts" or "follow our intuition." But is that always true? Are there times we should challenge our instincts? As highly sensitive people, we tend to get pretty potent "intuitive" messages from our bodies. But we are a conscientious and neurotic lot. So we also have a tendency to challenge our assumptions. How might we move in a way that both honors our intuition...but also use our natural inclination to challenge our thoughts in a way that is effective?