Is A Blood Brain Barrier Leak Causing Seizures? - Dr. Colin Doherty

Could inflammation and the blood-brain barrier help explain why some seizures remain uncontrolled? Prof. Colin Doherty discusses emerging research into immune activity in epilepsy, how steroids may temporarily improve seizure control, and why future immunotherapies could help some people whose seizures do not respond to current treatments. Chapters 📖00:00 Trailer & intro00:31 Precision therapy for autoimmune diseases01:27 Hypothesis: could steroids prevent seizures through mending the leakage of the Blood Brain Barrier? 03:53 Neurologists and researchers need to think about autoimmune04:57 Blood Brain Barrier, steroids and genetics - current study07:01 History: why haven’t we done this research already?08:13 Immunologists: work with us!09:48 Comparison: cancer and immunology12:08 Clinicians and scientists: work with us!13:51 People with an epilepsy and carers: work with us!15:27 Closing thoughts & thanks🔗 Episode page and transcript epilepsy-sparks-insights/autoimmune-therapy-blood-brain-barrier🌐 More about Colin epilepsysparks.com/guests/colin-doherty🌐 More Epilepsy Sparks Insights epilepsysparks.com/epilepsy-sparks-insights🎥 Watch on YouTube youtube.com/@EpilepsySparksInsights🔤 Don’t understand terms used? Check out the Epilepsy Sparks Glossary epilepsysparks.com/glossary📲 Join us on social media!〰️ LinkedIn epilepsy-sparks〰️ Instagram epilepsysparks〰️ Facebook epilepsysparks〰️ TikTok epilepsysparks〰️ Bluesky epilepsysparks​