Is Off-Label Drug Use Dangerous?

Send us Fan MailSummary: Off-label drug use rings of risk, of a doctor gone rogue, of an unknowing patient in danger.  But this issue - using drugs approved for one indication for a completely different use - is more common than you would think, and the reasons for this are simple and sensible.  This is a look at how an FDA-approved drug may launch in a trajectory for an intended indication, but may find itself in a different orbit:  off-label drugs.         Topics:·      Off Label Drug Use (OLDU) 02:00·      Approved Indications 02:45·      Benefit Outweighs Risk 03:25·      Monitoring Drug Usage:  Discovering New Uses 04:25·      FDA – Does NOT regulate practice of medicine 05:00·      No Advertising for OLDU 05:45·      Psych/Peds/Pregnant Women OLDU 06:45·      Physician Disclosure 07:00·      Mood Stabilizers (carbamazepine, valproate) 08:25·      Psych/Peds/Pregnant Women 09:10·      Why Not New Approval? 10:25·      Tricyclic Antidepressants (amitriptyline, Imipramine) OLDU 11:45·      Life Threatening Conditions 13:00·      Methotrexate 14:00·      Lantus Insulin 16:30·      Evidence that is accepted w/in profession of medicine 17:25·      Baclofen and Hiccups 18:00·      Hydroxychloroquine 19:00·      Orphan Drugs 20:10·      Emergency Use Authorization 21:25·      Gabapentin 22:15·      Monitor-Monitor-Monitor 22:30  Questions and comments to  [email protected]