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今天3分钟我们来聊聊前列腺癌新型免疫疗法:冷肿瘤反击战 episode artwork

EPISODE · Jun 1, 2026 · 5 MIN

今天3分钟我们来聊聊前列腺癌新型免疫疗法:冷肿瘤反击战

from 源于细胞BioInsid的个人播客

前列腺癌作为'冷肿瘤',传统免疫治疗效果不佳。新型疗法PSMA-CAR-T和T细胞衔接器(TCE)带来突破。PSMA-CAR-T通过改造T细胞精准打击癌细胞,临床试验中PSA降幅超75%;TCE架桥连接T细胞与肿瘤细胞,应答率近半。虽有细胞因子风暴等风险,但副作用较化疗更可控,为转移性去势抵抗患者带来希望。 参考文献: 前列腺癌的新型免疫疗法综述,Urologic Oncology: Seminars and Original Investigations, 2026年4月 PSMA-CAR-T I期临床数据(13例mCRPC患者)、BPX-601 GoCAR-T临床数据 Xaluritamig(STEAP1靶点TCE)I期、Pasritamig(KLK2×CD3靶点TCE)、Acapatamab(PSMA×CD3双特异性TCE)临床数据 Fred Hutch癌症中心、克利夫兰诊所专家评论 原文来源:源于细胞BioInside(Carmens Vision)公众号 前往小宇宙评论区与主播互动

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今天3分钟我们来聊聊前列腺癌新型免疫疗法:冷肿瘤反击战

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