Lethal Buttock Injection (And Other Toxicities of Illegal Cosmetic Body Fillers)

In this episode Ryan and Toxo dissect the fascinating underbelly of illegal cosmetic procedures and breakdown the toxicities that arise from them. IntroCase report of hemolysis after sodium deoxycholate injection HistoryEpidemiologyASPS statsFlorida Unlicensed Activity Unit Cost of surgeon fee for buttock implant 2018Recent new storiesBotox and Bubbles grifterQuick bio on cases mentioned in showCommon injection practicesFeminizing body contouring (pumping parties)Synthol musclesCapsule face cosmeticsToxicityInfectionSelf explanatoryFiller embolismReview 1, Review 2, Review 3Filler lodges in pulmonary vasculature->clotting, bleeding, inflammation95% occur within 72 hoursPrimarily respiratory symptoms (cough/hypoxemia)Chest x ray ground glass opacityTreat with supportive care (oxygen all the way through ECMO) +/- steroidsFiller BlindnessCRAO from body fillerNo effective treatment (exception, can use hyaluronidase if filler is hyaluronic acid)GranulomaInflammatory nodules from prolonged filler exposureMay occur months to year after injectionIllegal cosmetic= frequently lipogranuloma due to oil being present in many illegal cosmeticGranulomatous hypercalcemiaExcess calcitriol production from ganuloma causes hyperCACan be extremely delayed (up to 28 years)Recurrence up to 45%Treat with standard therapies (fluid, bisphosphonate) + steroids and/or ketoconazole to turn down granuloma CYP27B1 calcitriol productionCase from the showSome details changed for educational purposes Music in this episode from pixabay.comA Morel DilemmaSupport the showReview the show where ever your listeningGet Messages from Toxo (Join the Newsletter!)Join as a supporting memberAd free episodesBonus content and early accessDiscounts and give aways on GOTA PICCEM Mushroom card gameThe GOTTA PICCEM Poisonous Mushroom Game!The Poisonus Fungus Amongus Children's Book!Full book reading (6 minutes!)Tox trinkets (Rep the show at home!)Reach the showEmail: [email protected] Show ResourcesRyan's Medical Games and ResourcesShow Website