EPISODE · Sep 16, 2025 · 12 MIN
Liver, Fat, Ovaries... and Insulin. It's All Connected.
from PCOS Unfiltered: Nourish, Heal, Thrive · host Lindsie Vizethann
In this episode, I cover:Why insulin resistance is central — not just secondary — to PCOS symptomsWhat the 2023 Journal of Ovarian Research review reveals about insulin's impact on:The liver (glucose metabolism + fat production)Adipose (fat) tissue (hormone disruption + inflammation)The ovaries (androgen production + ovulation)How to understand insulin resistance beyond traditional glucose and A1c testingWhy fasting insulin is your early warning system — and how to ask for itTwo key treatment pathways:🌱 Lifestyle interventions (nutrition, mindful movement, strategic “add-ins”)💊 Pharmaceutical support (metformin, GLP-1s, and when they can help)How combining both strategies can significantly reduce PCOS symptoms and risksThe difference between managing and healing PCOS with the right approach📚 Referenced Research:https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-022-01091-0?.com💬 Don't miss our free, 3-night virtual event starting in October! Unwritten: Healing Beyond the DiagnosisI'll be joined by 5 other speakers who have healed beyond their own diagnosis and are giving you all the tools to do the same. Save your spot HERE!🎧 Subscribe + Review:If today’s episode gave you clarity or encouragement, hit subscribe and leave a quick ⭐⭐⭐⭐⭐ review—it helps more women like you find their way to real healing. 📘 Healthy for a Reason: 12 Practical Guidelines to Feel Like Yourself AgainIf you're tired of starting over, trying harder, and wondering why nothing seems to work, Healthy for a Reason was written for you.For years, we've been told the answer is more willpower, more restriction, and more rules. But if you've struggled with cravings, fatigue, emotional eating, poor sleep, or stubborn weight despite doing everything "right," you know it's not that simple.What if those struggles weren't signs that you've failed?What if they were your body's way of asking for something different?In Healthy for a Reason, Lindsie combines nearly two decades of nursing experience with practical health coaching strategies to help you understand what your body has been trying to tell you all along. You'll learn how to calm your nervous system, recognize your body's signals, build sustainable habits, and create lasting health by working with your body instead of constantly fighting against it.This isn't another diet book or a collection of quick fixes. It's a practical, compassionate guide to helping you reconnect with your body, rebuild trust in yourself, and finally understand why you're healthy for a reason.✨ Available now in paperback and Kindle.👉 Grab your copy HERE, available in paperback or on kindle 📝 Free Download: The Food Timeline TrackerUnlock the clues your body is already giving you.This simple worksheet helps you connect your meals to your hunger, cravings, and energy—so you can start spotting patterns, identifying insulin resistance symptoms, and making empowered food choices (no calorie counting required). Use it for just 2-3 days and prepare to be amazed at what you discover!✅ What's included:Meal tracking prompts (before, during, after, and long after)Space to note physical, emotional, and energy changesBonus reflection questions to guide your next steps📥 Grab it HERE!
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What this episode covers
In this science-backed episode of PCOS Unfiltered, we’re pulling back the curtain on one of the most misunderstood, under-diagnosed, and under-discussed root causes of PCOS: insulin resistance. (yes, again) Inspired by a 2023 review in the Journal of Ovarian Research, I break down how insulin resistance doesn’t just impact your blood sugar — it affects your liver, fat tissue, and ovaries, amplifying hormone imbalances and metabolic dysfunction. Whether you are told everything is “normal” or you’re navigating symptoms like irregular cycles, acne, or hair growth, this episode will help you understand what’s happening under the surface — and how to catch it early before it leads to long-term complications. You’ll learn why fasting insulin matters more than A1c, what the latest research says about treatment options (including lifestyle changes and medications like metformin and GLP-1s), and how to reclaim your health with real strategies that go beyond the fads.
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Liver, Fat, Ovaries... and Insulin. It's All Connected.
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