EPISODE · Sep 16, 2025 · 12 MIN
Liver, Fat, Ovaries... and Insulin. It's All Connected.
from PCOS Unfiltered: Nourish, Heal, Thrive · host Lindsie Vizethann
In this episode, I cover:Why insulin resistance is central — not just secondary — to PCOS symptomsWhat the 2023 Journal of Ovarian Research review reveals about insulin's impact on:The liver (glucose metabolism + fat production)Adipose (fat) tissue (hormone disruption + inflammation)The ovaries (androgen production + ovulation)How to understand insulin resistance beyond traditional glucose and A1c testingWhy fasting insulin is your early warning system — and how to ask for itTwo key treatment pathways:🌱 Lifestyle interventions (nutrition, mindful movement, strategic “add-ins”)💊 Pharmaceutical support (metformin, GLP-1s, and when they can help)How combining both strategies can significantly reduce PCOS symptoms and risksThe difference between managing and healing PCOS with the right approach📚 Referenced Research:https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-022-01091-0?.com💬 Don't miss our free, 3-night virtual event starting in October! Unwritten: Healing Beyond the DiagnosisI'll be joined by 5 other speakers who have healed beyond their own diagnosis and are giving you all the tools to do the same. Save your spot HERE!🎧 Subscribe + Review:If today’s episode gave you clarity or encouragement, hit subscribe and leave a quick ⭐⭐⭐⭐⭐ review—it helps more women like you find their way to real healing. 📘 Healing Beyond the Diagnosis: Rewrite Your PCOS Story to Finally Reclaim Your HealthIf you’re tired of chasing symptoms, starting over, and feeling disconnected from your body, this book was written for you.In Healing Beyond the Diagnosis, Lindsie guides you beyond labels and quick fixes and into a deeper understanding of what your symptoms are actually communicating. This book blends science, lived experience, and compassionate insight to help you rebuild trust with your body, calm your nervous system, and create sustainable, lasting health — without restriction, shame, or burnout.✨ Perfect for women with PCOS who want clarity, confidence, and a path forward that finally makes sense.👉 Grab your copy HERE, available in paperback or on kindle 📝 Free Download: The Food Timeline TrackerUnlock the clues your body is already giving you.This simple worksheet helps you connect your meals to your hunger, cravings, and energy—so you can start spotting patterns, identifying insulin resistance symptoms, and making empowered food choices (no calorie counting required). Use it for just 2-3 days and prepare to be amazed at what you discover!✅ What's included:Meal tracking prompts (before, during, after, and long after)Space to note physical, emotional, and energy changesBonus reflection questions to guide your next steps📥 Grab it HERE!
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What this episode covers
In this science-backed episode of PCOS Unfiltered, we’re pulling back the curtain on one of the most misunderstood, under-diagnosed, and under-discussed root causes of PCOS: insulin resistance. (yes, again) Inspired by a 2023 review in the Journal of Ovarian Research, I break down how insulin resistance doesn’t just impact your blood sugar — it affects your liver, fat tissue, and ovaries, amplifying hormone imbalances and metabolic dysfunction. Whether you are told everything is “normal” or you’re navigating symptoms like irregular cycles, acne, or hair growth, this episode will help you understand what’s happening under the surface — and how to catch it early before it leads to long-term complications. You’ll learn why fasting insulin matters more than A1c, what the latest research says about treatment options (including lifestyle changes and medications like metformin and GLP-1s), and how to reclaim your health with real strategies that go beyond the fads.
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Liver, Fat, Ovaries... and Insulin. It's All Connected.
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