Low-Dose Naltrexone (Aka LDN): What It Is, Who It May Help + Why We Use It episode artwork

EPISODE · Aug 26, 2026 · 12 MIN

Low-Dose Naltrexone (Aka LDN): What It Is, Who It May Help + Why We Use It

from The Well Made Podcast · host Brookes Vaughan

Have you been hearing about LDN and wondering what all the fuss is about?In today’s episode, Brookes Vaughan, WHNP-BC, and Kate Greene, RN & practice director break down low-dose naltrexone—what it is, how it differs from traditional naltrexone dosing, why we often use it in practice, and what you should know before considering it.At very low doses, naltrexone is used off-label and is being studied for its potential role in areas like inflammation, immune regulation, chronic pain, metabolic health, and more. And for the right patient, we’ve seen it be a really helpful tool.We’re talking about:What LDN actually isWhy the dose mattersHow it may impact inflammation and immune functionWho might benefitPotential side effects and considerationsWhy it’s definitely not a one-size-fits-all medicationIf you’ve ever thought, “Wait… isn’t naltrexone used for something completely different?”—this episode is for you.Listen now and send it to a friend who keeps hearing about LDN but has no idea what it actually does.

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Low-Dose Naltrexone (Aka LDN): What It Is, Who It May Help + Why We Use It

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